Code
DOCT/000881
Duration
07 October 2021 → 20 September 2026 (Ongoing)
Doctoral researcher
Research disciplines
-
Medical and health sciences
- Inflammation
- Innate immunity
Keywords
inflammation
A20
itaconate
viral infection
Project description
This PhD project aims to clarify the importance of A20 phosphorylation for its anti-inflammatory function. Next to this, the project will investigate the role of the metabolite itaconate (itaconic acid) and A20 in myeloid cells in the antiviral immune response against influenza A virus (IAV) and pneumonia virus of mice (PVM) infection.