Project

Investigating critical mediators of inflammatory disease

Code
DOCT/000881
Duration
07 October 2021 → 20 September 2026 (Ongoing)
Doctoral researcher
Research disciplines
  • Medical and health sciences
    • Inflammation
    • Innate immunity
Keywords
inflammation A20 itaconate viral infection
 
Project description

This PhD project aims to clarify the importance of A20 phosphorylation for its anti-inflammatory function. Next to this, the project will investigate the role of the metabolite itaconate (itaconic acid) and A20 in myeloid cells in the antiviral immune response against influenza A virus (IAV) and pneumonia virus of mice (PVM) infection.