Project

The physiology of superlongevity

Duration
01 October 2012 → 30 September 2017
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Systems biology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
Keywords
ageing physiology C. elegans transcriptomics
 
Project description

The lifespan of the nematode Caenorhabditis elegans will be extended drastically by combining mutations and changing the dietary regimen. Next, the physiology of the superlong-lived worm will be characterized by transcriptome analysis and in vivo quantification of energy metabolism, reactive oxygen species and protein turnover.