Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Project

The role of the Wiskott-Aldrich Syndrome protein (WASp) in human T cell development and on the development of the T cell repertoire.

Information

Project Team

Outputs and Outcomes

Publications

Gene editing-based targeted integration for correction of Wiskott-Aldrich syndrome

Melissa PilleJohn M. AvilaSo Hyun ParkCuong Q. LeHaipeng XueFilomeen HaerynckLavanya SaxenaCiaran LeeElizabeth J. ShpallGang BaoBart VandekerckhoveBrian R. Davis et al.

A1 Journal Article in MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT

2024

The Wiskott–Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation

Melissa PilleJohn AvilaGuillem Sanchez SanchezGlenn GoetgelukStijn De MunterHanne JansenLore BillietKarin WeeningHaipeng XueSarah BonteJoline IngelsLaurenz De CockEva PascalLucas DeseinsTessa KerreTom TaghonGeorges LeclercqDavid VermijlenBrian DavisBart Vandekerckhove et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

2023