01 October 2010 → 30 August 2013
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
- Systems biology
cell death TNF necroptosis necrosis
We aim to further dissect regulated necrosis, by means of high trouhgpu 5HT) and heigh content screening (HTS) using automated microscopy. The identified mechanism will eventually be validated by in vivo disease model systems in which necrotic ceel death mechanisms is presumed to play a major role (TNF-induces shick, inflammatory bowel disease, diabetes, ischemia/reperfusion).