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Project

Generation and detailed analysis of novel tools to study the importance of dimerization of the Glucocorticoid Receptor in inflammation.

Outputs and Outcomes

Code

3F025615

Duration

01 October 2015 → 30 September 2019

Funding

Research Foundation - Flanders (FWO)

Promotor

Claude Libert

Fellow

Lise Van Wyngene

Research disciplines

Natural sciences
- Genetics
- Systems biology
- Other biological sciences
Medical and health sciences
- Immunology
- Molecular and cell biology
- Immunology
- Immunology
- Molecular and cell biology

Keywords

TNF enhancers Glucocorticoid Receptor (GR) Transcription factors Systemic Inflammatory Response Syndrome dimerization

Project description

Novel tools to study the importance of dimerization of the GR wil be generated and investigated. Cells and mice will be generated with inducible GR dimerization and these will be used to study the role of GR dimerization in the control of SIRS.

English

Dutch

English

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