Research Explorer

Project

Development and application of NMR diffusion and relaxation techniques for the characterisation of supramolecular structures and self-assembly
Code
01P10810
Duration
01 January 2011 → 31 December 2013
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Analytical chemistry
    • Organic chemistry
    • Physical chemistry
Keywords
self-assembly structure-function relationship NMR spectroscopy
 
Project description
 

New NMR techniques, based on diffusion and relaxation measurements, will be developped to study supramolecular assemblies. These will be applied within the framework of the structure-function relationship study of synthetic variants of the biological active pseudodesmin A, a self-assembling cyclic lipodepsipeptide. Furthermore, the impact of biomolecular self-association on the relaxation parameters and the impact on dynamics studies will be investigated.