Project

Structure, self-assembly and function of cyclic lipodepsipeptides from Pseudomonads by drafting their bacterial biosynthetic machinery for NMR spectroscopic duty

Duration
01 October 2016 → 30 September 2020
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Engineering and technology
    • Catalysis and reacting systems engineering
    • Chemical product design and formulation
    • General chemical and biochemical engineering
    • Process engineering
    • Separation and membrane technologies
    • Transport phenomena
    • Other (bio)chemical engineering
Keywords
molecular analysis
 
Project description

Cyclic lipodepsipeptides from Pseudomonas bacteria display a very diverse set of biological functions and activities. By elucidating the structure of new representatives and study their intermolecular association – partly using a novel and advanced approach that involves stable isotope labelled compounds obtained through biosynthesis – our understanding of the structure-function relationship will achieve a much higher level than currently available.