Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Project

Unlocking the specificity determinants in nucleotide sugar epimerases

Information

Project Team

Organisations

Outputs and Outcomes

Publications

Protein flexibility drives sugar rotation and high substrate promiscuity in a GDP-sugar 4-epimerase

Carlos Alvarez QuispeKoen BeerensAndy-Mark W.H. ThunnissenXevi BiarnésAntoni PlanasTom Desmet

A1 Journal Article in COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL

2025

The conversion of UDP-Glc to UDP-Man : in silico and biochemical exploration to improve the catalytic efficiency of CDP-tyvelose C2-epimerases

Ulrike VogelMatthieu Da CostaCarlos Alvarez QuispeRobin StragierHenk‐Jan JoostenKoen BeerensTom Desmet

A1 Journal Article in CHEMBIOCHEM

2023

Exploration of archaeal nucleotide sugar epimerases unveils a new and highly promiscuous GDP-Gal4E subgroup

Carlos Alvarez QuispeMatthieu Da CostaKoen BeerensTom Desmet

A2 Journal Article in CURRENT RESEARCH IN BIOTECHNOLOGY

2022