Research Explorer

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Project

Investigating the function and development of ‘lipid-associated macrophages’ (LAMs) in liver fibrosis across species.

Outputs & Impact

Publications & research data ( 7 )

Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

Federico Francesco De PontiAnna BujkoZhuangzhuang LiuPaul CollinsSara SchuermansChristian MaueröderSeraja AmstelveenTinne ThonéLiesbet MartensJohn McKendrick et al.

A1 Journal Article in IMMUNITY

Understanding the complex macrophage landscape in MASLD

Federico Francesco De PontiZhuangzhuang LiuCharlotte Scott

A1 Journal Article in JHEP REPORTS

Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis

Kevin De MuynckLander HeyerickFederico Francesco De PontiBart VanderborghtTim MeeseSanne Van CampenhoutLeen BaudonckEva GijbelsPedro M. RodriguesJesus M. Banales et al.

A1 Journal Article in HEPATOLOGY

Limitations of PLX3397 as a microglial investigational tool : peripheral and off-target effects dictate the response to inflammation

Wouter ClaeysDaan VerhaegeGriet Van ImschootElien Van WonterghemLore Van AckerLaura AmelinckFederico Francesco De PontiCharlotte ScottAnja GeertsChristophe Van Steenkiste et al.

A1 Journal Article in FRONTIERS IN IMMUNOLOGY

Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis

Kevin De MuynckBart VanderborghtFederico Francesco De PontiEva GijbelsSophie Van WeldenMartin GuilliamsCharlotte ScottAlain BeschinMathieu VinkenSander Lefere et al.

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

A breath of fresh macrophages ameliorates inflammation in the hypoxic lung

Federico Francesco De PontiCharlotte Scott

Editorial material

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

Martin GuilliamsJohnny BonnardelBirthe HaestBart VanderborghtCamille WagnerAnneleen RemmerieAnna BujkoLiesbet MartensTinne ThonéRobin Browaeys et al.

A1 Journal Article in CELL

Activities ( 0 )

Results

Impact narratives ( 1 )

Medicine: liver

Area(s): Health

Patents ( 0 )