When settlers invaded North America, they brought with them a host of organisms which drastically changed the landscapes they encountered, replacing native flora, fauna and Indigenous people (Crosby 2004). This project describes and analyzes the process of species invasion in terms of plants and the role they played in the settlement of Western Canada in the late nineteenth century, asking first, how colonial capitalist organization of the landscape enabled these ‘creatures of empire’ (Anderson 2006) to flourish and second, how they facilitated the invasion and colonization of Alberta, through the destruction and control of Indigenous peoples and their ecologies. In addition I ask how (contemporary) human scientific and technological responses to these unwanted weeds have been incorporated in human programs of ‘invasion, empire or capital’ (Tsing et al. 2020), further killing possibilities for multispecies entanglements to thrive. Lastly, I look at alternative collaborations that try to create spaces for multispecies survival, asking what attention to and care for native plants can contribute.