Project

Analysis of the effect of caloric restriction on the choroid plexus epithelial (CPE) cells that form the blood-cerebrospinal fluid barrier (BCSFB).

Duration
01 October 2015 → 30 September 2019
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Other chemical sciences
    • Other biological sciences
  • Medical and health sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other basic sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other clinical sciences
    • Other health sciences
    • Nursing
    • Nutrition and dietetics
    • Other paramedical sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other translational sciences
    • Other medical and health sciences
  • Agricultural and food sciences
    • Agricultural animal production
    • Food sciences and (bio)technology
Keywords
caloric restriction (CR) blood-cerebrospinal fluid barrier (BCSFB) choroid plexus epithelial (CPE) cells Alzheimer’s disease (AD)
 
Project description

Recent research has provided solid ground to the concept that limiting calorie intake slows down brain aging and protects from age-related neurodegenerative diseases. The goal of this project is to study the link between caloric restriction and the choroid plexus epithelial (CPE) cells that form the blood-cerebrospinal fluid barrier (BCSFB), both in healthy conditions and in the age-related disease Alzheimer’s.