Research Explorer

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Project

Scrutinizing selective Aurora Kinase A inhibition as a novel entry point for synthetic lethality in neuroblastoma

Outputs and Outcomes

Publications

Exploration of neuroblastoma xenograft models for tumor extracellular RNA profiling in murine blood plasma

Jill DeleuHanne Van DroogenbroeckJasper AnckaertAnneleen DecockJilke De WildeKaat DurinckLiselot MusJustine NuytensMuhammad RishfiKathleen SchoofsFranki SpelemanMaaike Van TrimpontKimberly VerniersNurten YigitJo VandesompeleBram De WildeTom Van Maerken et al.

A2 Journal Article in EXRNA

Targeted AURKA degradation : towards new therapeutic agents for neuroblastoma

Muhammad RishfiSimon KrolsFien MartensSarah-Lee BekaertEllen SandersAline EggermontFanny De VloedJoshua Robert GouldingMartijn RisseeuwJan MolenaarBram De WildeSerge Van CalenberghKaat Durinck et al.

A1 Journal Article in EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA

Vanessa VermeirssenJill DeleuAnnelien MorlionCeline EveraertJilke De WildeJasper AnckaertKaat DurinckJustine NuytensMuhammad RishfiFranki SpelemanHanne Van DroogenbroeckKimberly VerniersMF BaiettiM AlbersenE LeucciE PostMG BestTom Van MaerkenBram De WildeJo VandesompeleAnneleen Decock et al.

A2 Journal Article in NAR CANCER

RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition

Carolina de Carvalho NunesLisa DepestelLiselot MusKaylee M. KellerLouis DelhayeAmber LouwagieMuhammad RishfiAlex WhaleNeesha KaraSimon R. AndrewsFilemon Dela CruzDaoqi YouArmaan SiddiqueeCamila Takeno ColognaSam De CraemerEmmy DolmanChristoph BartenhagenFanny De VloedEllen SandersAline EggermontSarah-Lee BekaertWouter Van LoockeJan Willem BekGivani DewynSiebe LoontiensGert Van IsterdaelBieke DecaestekerLaurentijn TillemanFilip Van NieuwerburghVanessa VermeirssenChristophe Van NesteBart GhesquièreSteven GoossensSven EyckermanKatleen De PreterMatthias FischerJon HouseleyJan MolenaarBram De WildeStephen S. RobertsKaat DurinckFranki Speleman et al.

A1 Journal Article in SCIENCE ADVANCES