Research Explorer

Project

The pathomechanism of spontaneous peripheral neuropathy in aging rats
Code
01D41113
Duration
01 October 2013 → 30 September 2017
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
  • Social sciences
    • Biological and physiological psychology
    • Cognitive science and intelligent systems
    • Developmental psychology and ageing
  • Medical and health sciences
    • Gerontology and geriatrics
    • Neurosciences
    • Gerontology and geriatrics
    • Neurosciences
    • Nursing
    • Gerontology and geriatrics
    • Neurosciences
  • Agricultural and food sciences
    • Veterinary medicine
    • Other veterinary sciences
    • Other agricultural and food sciences
Keywords
Rattus norvegicus gerontology rat hind leg paralysis neuropathie
 
Project description
 

In ageing rats, there is a high incidence of spontaneous peripheral neuropathy, resulting in hind limb paresis, evolving to complete hind limb

paralysis. Lesions developing in the rats’ peripheral nervous system will be followed up

in vivo, using Diffusion Tensor Imaging (DTI) and electrophysiological examination. Thereafter, early pathobiology of the disorder will be studied more in depth.