Research Explorer

Project

Identification of molecular cues mediating inflammation and tumorpromoting properties of skin fibroblasts
Code
3PS01614
Duration
01 February 2015 → 15 February 2016
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Cell signalling
  • Medical and health sciences
    • Regenerative medicine not elsewhere classified
Keywords
immunology Inflammation skin cancer
 
Project description
 

Fibroblasts are stromal cells that can produce extracellular matrix proteins and are able to mediate epithelial growth and oncogenic potential. In this proposal, we aim to identify the molecular switches that tip the balance between the epithelial growth inhibitory and promoting roles of skin fibroblasts during inflammation and oncogenic transformation.