Project

doctoraatsproject Angelica Thelen: Manufacture, functionalization and application of designed inorganic supports for enzyme immobilization.

Code
180J3416
Duration
01 March 2016 → 29 February 2020
Funding
Regional and community funding: various
Promotor
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
Keywords
enzyme carrier materials enzyme biocatalysis
 
Project description

In the last two decades, biocatalysis has emerged as an important technology for meeting the growing demand for green and sustainable chemicals manufacture, particularly in the synthesis of pharmaceuticals, flavor and fragrances, vitamins and other fine chemicals. Despite the advantages, the long-term operational stability and difficult recovery and re-use of the enzyme limit their wide-spread industrial application. These drawbacks can generally be overcome by immobilization of the enzyme. Along with better stability under storage and operational conditions enzyme immobilization also facilitates the efficient recovery and re-use of the enzyme and widens de application potential of enzyme technology in a variety of domains. These evolutions trigger a constant need for designed enzyme carrier materials and improved immobilization methods, which are difficult to meet by the existing materials.

Therefore, tis project aims at the use of advanced powder shaping technology and surface modification technologies to manufacture, functionalize and benchmark structured inorganic materials designed for use as enzyme immobilization carriers.