Research Explorer

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Project

Development and fundamental evaluation of high efficiency capillary liquid chromatography

Outputs and Outcomes

Code

3G043809

Duration

01 January 2009 → 31 December 2014

Funding

Research Foundation - Flanders (FWO)

Promotor

Frederic Lynen

Research disciplines

Natural sciences
- Analytical chemistry
Medical and health sciences
- Pharmaceutical analysis and quality assurance

Keywords

mass spectrometry HPLC chromatography nano-LC efficiency high resolution analyse micro-LC

Project description

The goal of the project is to evaluate and develop columns for capillary LC. Much increased MS sensitivity can be obtained by cap-LC because of the enhanced ionization efficiency. The decreased thermal mass of capillary columns allows to benefits of high temperature (gradient) LC. The project is aimed at manufacturing high efficiency capillary columns for high resolution LC and for the analysis of complex samples.

English

Dutch

English

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