Unraveling the role of S100-DAMPs in seronegative arthritis

01 October 2013 → 30 September 2017
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Orthopaedics
    • Orthopaedics
    • Orthopaedics
arthritis innate immunity inflammation
Project description

Our goal is to link expression patterns of S100 DAMPs, important drivers of innate immunity, with their mechanistic role in the pathogenesis of joint inflammation in seronegative arthritis. We will use a translational approach combining a variety of unique tools with valuable human samples and multiple validated mouse models.