Research Explorer

Project

Development and evaluation of specific strategies for the targeted labeling of intracellular structures with quantum dots in live cells
Code
31509012
Duration
01 January 2012 → 31 December 2014
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Applied mathematics in specific fields
  • Medical and health sciences
    • Biomarker discovery and evaluation
    • Drug discovery and development
    • Medicinal products
    • Pharmaceutics
    • Pharmacognosy and phytochemistry
    • Pharmacology
    • Pharmacotherapy
    • Toxicology and toxinology
    • Other pharmaceutical sciences
  • Engineering and technology
    • Materials science and engineering
Keywords
quantum dots cell labeling nanoparticles
 
Project description
 

The current project focuses on the intracellulair delivery of fluorescent nanomaterials (quantum dots), where several technologies will be evaluated to obtain cytoplasmic delivery. Both heat-generating particles and the combination of ultrasound and quantum dots will be tested in generating membrane pores, where cytoplasmic delivery will be compared to the level obtained by microinjection