A chronic rhinosinusitis cohort study will be launched in the framework op WP 2.7.2.
It will consist in a cross-sectional study which will aim to further differentiate chronic sinus diseases by measurement of inflammatory mediators, and a longitudinal study with a cohort of early sinus disease. The goal of the cross-sectional study is to have 800 patients and 200 controls included. This will result in a chronic rhinosinusitis biobank of approximately 250 patients and 50 "control" individuals.
The term chronic rhinosinusitis covers a heterogeneous group of diseases that consitute one of the most common health care problems, with significant direct medical costs as well as severe impact on lower airway disease and general health outcomes.