Project

Biological image-guided intensity modulated radiation therapy (BG-IMRT)

Duration
01 January 2007 → 31 December 2009
Funding
Funding by bilateral agreement (private and foundations)
Research disciplines
  • Medical and health sciences
    • Medical imaging and therapy
    • Morphological sciences
    • Oncology
    • Medical imaging and therapy
    • Morphological sciences
    • Oncology
    • Other paramedical sciences
    • Medical imaging and therapy
    • Morphological sciences
    • Oncology
Keywords
IGRT pet IMRT
 
Project description

The present project comprises 3 clinical studies that will 1) test feasibility of PET imaging with tracers such as FLT (proliferation), EF3 and/or FMISO (hypoxia) in head and neck cancer and in colorectal cancer 2) test the improvement in local control in head and neck cancer with FDG-PET based BG-IMRT using a randomized controlled prospective phase II study 3) increaese the rate of negative circumferential resection margins (CRM) in patients diagnosed with locally advanced rectal cancers with positive circumferential resection margin (CRM) in a phase II study.