Code
179J14013
Duration
01 January 2013 → 31 December 2016
Funding
Regional and community funding: various
Promotor
Research disciplines
-
Natural sciences
- Applied mathematics in specific fields
- Computer architecture and networks
- Distributed computing
- Information sciences
- Information systems
- Programming languages
- Scientific computing
- Theoretical computer science
- Visual computing
- Other information and computing sciences
- Bioinformatics and computational biology
- Microbiology
- Systems biology
-
Medical and health sciences
- Bioinformatics and computational biology
- Laboratory medicine
- Microbiology
- Bioinformatics and computational biology
- Laboratory medicine
- Public health care
- Public health services
- Bioinformatics and computational biology
- Laboratory medicine
- Microbiology
-
Engineering and technology
- Scientific computing
Keywords
drug development
bacterial biofilm
network-based dataintegration
Project description
Drug repurposing and the design of polypharmacological and drug-cocktailing strategies by combining in-house phenotypic and molecular data with advanced bioinformatics approaches. This implies 1) constructing drug-target networks,
2) constructing interaction networks from publicly available data, 3) determining the mode of action of drugs by interrogating interaction networks with in-house data, 4) testing the phenotypic and molecular effect of anti-biofilm agents.