Stress and bovine sperm in relation to in vitro fertility

08 March 2012 → 07 March 2013
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Animal biology
    • General biology
  • Agricultural and food sciences
    • Veterinary medicine
oocyte quality peroxiredoxin spermatozoa
Project description

"If it doesn't kill you it makes you stronger". Sublethal stress can improve gamete quality. In this research we will investigate the peroxiredoxins (PRDXs) expression in bull spermatozoa after H2O2 exposure and their role in sperm-oocytes interaction. Moreover, we will evaluate the expression pattern of PRDX6 in oocytes of different quality (small, medium and large oocytes, based on oocyte diameter) and its role in repairing oxidative sperm DNA damage and subsequent in vitro embryo production.