Research Explorer

Project

Influencing factors of human endogenous pain modulation
Code
01CD17324
Duration
01 February 2025 → 30 September 2025
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Medical and health sciences
    • Rehabilitation
Keywords
exercise program temporal summation of pain genetic predisposition conditioned pain modulation low back pain Experimental pain quantitative sensory testing fibromyalgia distraction nociceptive flexion reflex expectations attention exercise-induced hypoalgesia physical activity
 
Project description
 The body’s pain modulation system regulates nociceptive signals through facilitation and inhibition, evaluated using experimental pain measurements. Which factors influence the outcome of these pain measurements, as a proxy of endogenous pain modulation, and in what way is not yet clear. This study examines the influence of such factors (e.g., cognition, physical activity, genetics) and interventions on experimental pain measurements.