Research Explorer

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Project

The role of superantigens in local IgE production in the nose

Outputs and Outcomes

Code

01J18707

Duration

01 January 2007 → 31 October 2011

Funding

Regional and community funding: Special Research Fund

Promotor

Claus Bachert

Research disciplines

Medical and health sciences
- Otorhinolaryngology
- Otorhinolaryngology
- Speech, language and hearing sciences
- Otorhinolaryngology

Keywords

IgE superantigens sinusitis

Project description

In this project we will study the mechanisms leading to a local IgE production in allergic rhinitis and nasal polyposis. The influence of superanitgens on the immune response and the role of polyclonal IgE in the pathofysiology will be investigated. Finally therapeutic strategies to microbial triggers or to local IgE in Nasal polyps will be tested.

English

Dutch

English

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