Code
3E020916
Duration
01 October 2016 → 31 December 2020
Funding
Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Natural sciences
- Genetics
- Systems biology
-
Medical and health sciences
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
- Laboratory medicine
- Medical systems biology
- Molecular and cell biology
Keywords
cancer
neuroblastoma
replicative stress
Project description
Fast dividing embryonic stem and cancer cells are subject to stress during DNA replication. G-quadruplexes (G4s) are DNA secondary structures formed by G-rich regions in the DNA, and have recently been shown to play a key role in embryonic stem cell and cancer cell replicative stress. I will apply in-depth bioinformatics analysis on this subject.