Project

Apoptosis, necrosis and autophagy: a comparative study of the impacht of dying cells on innate immunity

Duration
01 October 2008 → 15 October 2014
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Research disciplines
  • Medical and health sciences
    • Immunology
    • Physiology
    • Immunology
    • Physiology
    • Immunology
    • Physiology
Keywords
inflammation phagocytosis dying cells
 
Project description

The aim of this project is to investigate in a comparative way the interaction and communication of different types of dying ells (apoptotic, necrotic and autophagic) with the innate immune system. In the second part of this project we will perform molecular identification, characterization and validation of DAMPs (death associated molecular patterns), which are involved in the immunomodulatory properties of dying cells.