Project

Necroptosis, a well controlled cell death modality – its role in tumor development and how to exploit this therapeutically

Duration
01 January 2012 → 31 December 2017
Funding
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Other biological sciences
Keywords
cell death tumor necroptosis
 
Project description

This research project wants to study the role of necroptosis in immunogenicity of
apoptotic and necroptotic tumor models as well as its role in spontaneous and
inducible tumor development using transgenic mice. Moreover we want to re-evaluate
existing drugs and discover new drugs for their potential to sensitize/induce
necroptosis.