Project

Circulating histidine-containing dipeptides and the development of diabetic nephropathy: role of exercise and supplementation

Code

3E006614

Duration

01 October 2014 → 03 January 2021

Funding

Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)

Promotor

Wim Derave

Fellow

Inge Everaert

Research disciplines

Social sciences
- Education curriculum
Medical and health sciences
- Endocrinology and metabolic diseases
- Physiology
- Endocrinology and metabolic diseases
- Physiology
- Endocrinology and metabolic diseases
- Physiology

Keywords

carnosine nephropathy aerobic training

Project description

Both supplementation with the dipeptide carnosine and aerobic training have been shown, at least in rodents, to protect against the development of diabetic nephropathy. The goal of this project is to elucidate whether this exercise-induced protection can be attributed, at least partly, to elevated circulating histidine-containing dipeptides levels.