Project

The environmental niche of Burkholderia multivorans: fitness school for a cystic fibrosis pathogen?

Duration
01 October 2011 → 30 September 2015
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Microbiology
    • Systems biology
  • Medical and health sciences
    • Laboratory medicine
    • Microbiology
    • Laboratory medicine
    • Laboratory medicine
    • Microbiology
Keywords
MALDI-TOF Burkholderia multivorans mobile genetic elements cystic fibrosis mass spectrometry whole genome studies MLST
 
Project description

The present project aims to explore the environmental niche of Burkholderia multivorans and to determine its population structure. Comparative whole genome studies should reveal the presence of mobile genetic elements and allow to characterize their genetic determinants. These will be mapped on a large collection of environmental and clinical strains in order to reveal mechanisms of genetic adaptation in this cystic fibrosis pathogen.