Project

Using advanced fluid dynamics modelling for cardiovascular phenotyping of zebrafish models

Code
01IO3818
Duration
01 October 2018 → 30 September 2022
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Engineering and technology
    • Biofluid mechanics
    • System and whole body biomechanics
    • Biomechanical engineering not elsewehere classified
    • Modelling and simulation
    • Fluid mechanics and fluid dynamics
Keywords
Cardiovascular zebrafish animal models fluid dynamics fluid-structure interaction computer modelling
 
Project description

Taking advantage of interdisciplinary know-how in life sciences and engineering, this project uses a concerted approach to develop novel fluid dynamics models for blood flow in both larval and adult zebrafish. These models will be applied in zebrafish strains carrying engineered genetic mutations that lead to cardiovascular abnormalities, in order to assess their impact on advanced hemodynamic parameters.