Code
01IO3818
Duration
01 October 2018 → 30 September 2024
Funding
Regional and community funding: Special Research Fund
Promotor
Research disciplines
-
Engineering and technology
- Biofluid mechanics
- System and whole body biomechanics
- Biomechanical engineering not elsewehere classified
- Modelling and simulation
- Fluid mechanics and fluid dynamics
Keywords
Cardiovascular
zebrafish
animal models
fluid dynamics
fluid-structure interaction
computer modelling
Project description
Taking advantage of interdisciplinary know-how in life sciences and engineering, this project uses a concerted approach to develop novel fluid dynamics models for blood flow in both larval and adult zebrafish. These models will be applied in zebrafish strains carrying engineered genetic mutations that lead to cardiovascular abnormalities, in order to assess their impact on advanced hemodynamic parameters.