Research Explorer

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Project

Conformationally locked G4-decoy oligonucleotides for selective telomerase inhibition and development of a nucleic acid-based anti-telomerase PROTAC strategy

Outputs & Impact

Publications & research data ( 8 )

From loops to caps : discriminating peptide binding to distinct G-quadruplex tetrads using 5-furyl-2′-deoxyuridine fluorescent probes

Jack BarrTayler D. Prieto OtoyaChristine CardinEnrico Cadoni

A2 Journal Article in RSC CHEMICAL BIOLOGY

Development of 'furan warhead'-equipped antagonistic nanobodies for covalent cross-linking to the epidermal growth factor receptor

Laure TackLaia Miret CasalsOlivier ZwaenepoelEnrico CadoniMarleen Van TroysJan GettemansAnnemieke Madder

A1 Journal Article in BIOCONJUGATE CHEMISTRY

Development of a His-Tag-mediated pull-down and quantification assay for G-quadruplex containing DNA sequences

Enrico CadoniHanne MoermanAnnemieke Madder

A2 Journal Article in RSC CHEMICAL BIOLOGY

Locking up G-quadruplexes with light-triggered staples leads to increased topological, thermodynamic, and metabolic stability

Jack BarrEnrico CadoniSofie SchellinckEmiliano LaudadioJosé MartinsAnnemieke Madder

A1 Journal Article in ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Exploiting G-quadruplex-DNA damage as a tool to quantify singlet oxygen production

Lessandro De PaepeAnnemieke MadderEnrico Cadoni

A1 Journal Article in SMALL METHODS

Furan-modified PNA probes for covalent targeting and ligation of nucleic acids

Lessandro De PaepeEnrico CadoniAlex ManicardiAnnemieke Madder

A1 Journal Article in METHODS

Furan-based (photo)oxidation reactions and their application in nucleic acid and protein targeting

Jack BarrGertjan ColpaertEnrico CadoniAnnemieke Madder

A1 Journal Article in METHODS

A red light-triggered chemical tool for sequence-specific alkylation of G-quadruplex and I-motif DNA

Enrico CadoniLessandro De PaepeGertjan ColpaertRuben TackDries WaegemanAlex ManicardiAnnemieke Madder

A1 Journal Article in NUCLEIC ACIDS RESEARCH

Activities ( 0 )

Results

Impact narratives ( 0 )

Patents ( 0 )