Code
3F003515
Duration
01 October 2015 → 30 September 2019
Funding
Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Immunology
- Morphological sciences
- Oncology
- Immunology
- Morphological sciences
- Oncology
- Biomarker discovery and evaluation
- Drug discovery and development
- Medicinal products
- Pharmaceutics
- Pharmacognosy and phytochemistry
- Pharmacology
- Pharmacotherapy
- Toxicology and toxinology
- Other pharmaceutical sciences
- Immunology
- Morphological sciences
- Oncology
Keywords
cancer
gene therapy
cell migration
Project description
This research focuses on the use of cellular vehicles for the delivery of therapeutic agents. These carriers are used as Trojan horses to deposit nucleic acid constructs that code for anti-cancer agents in the vicinity of a tumor. Additionally, the constructs possess regulatory elements which allow external regulation of the production of these agents. In brief, this model aims to provide researchers and clinicians a tool to specifically target malignant regions of interest without the need for high systemic concentrations and their associated adverse effects.