Studying of enrofloxacin resistance prevalence in APEC isolates of broiler chickens in Kenya

OPG 2020 - Devreese
01 January 2020 → Ongoing
Federal funding: VLIR-UOS
Research disciplines
  • Agricultural and food sciences
    • Veterinary pharmacology and toxicology
    • Veterinary public health and food safety
enrofloxacin antimicrobial resistance poultry Kenya
Project description

Current dosage regimens of antimicrobials have been determined for treatment without taking antimicrobial resistance into account. Enrofloxacin is commonly used to treat avian pathogenic Escherichia coli (APEC) infections. Hence, the first aim is to investigate the current enrofloxacin resistance prevalence in clinical APEC isolates in Kenya. Through PK/PD modelling the posology of the antimicrobial will be optimized for Kenyan broilers chickens taking the current resistance pattern of APEC towards enrofloxacin into account. This will lead to a reduced development and selection of antimicrobial resistance for this particular pathogen.