Project

Solid-phase synthesis of stucturally diverse benzodiazocines for application in combinatorial libraries

Duration
01 October 2008 → 30 September 2012
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Organic chemistry
Keywords
benzodiazocines solid-phase synthesis combinatorial libraries privileged scaffolds
 
Project description

The aim of this research project is the synthesis of novel "priviledged scaffolds" (classes of compounds possessing affinity for a number of different receptor types) for drug design. We will focus on the benzodiazocine skeleton, developing methods for attaching side chains to different positions of the scaffolds, making use of combinatorial chemistry.