Project

Deciphering the localization dynamics of BRI1-mediated signaling by the proteome

Duration
01 September 2015 → 30 June 2020
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Biochemistry and metabolism
    • Plant biology
    • Systems biology
  • Medical and health sciences
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
    • Medical biochemistry and metabolism
Keywords
receptor-mediated signalling endocytosis brassinosteroids
 
Project description

Here, we will use the brassinosteroid hormone receptor, BRI1, as a model to define the molecular framework of the interaction between signaling and endocytosis. By combining proteomics approach with genetic and chemical perturbations we will identify the endocytic machinery of BRI1 which, when combined with known signaling components, will allow us to develop an integrated model of receptor-mediated signaling and endocytosis in plants.