The successful research in Tissue Engineering and Biomaterials heavily depends on the development of innovative cell-interactive materials, deeper understanding of the stem cell niche function and introduction of more physiologically relevant 3D cell & tissue models, such as multi-cellular spheroids and organoids from small intestine, human brain and others. Our team addresses these challenges by developing bio- and nanosensors for monitoring cell and tissue hypoxia, metabolism, nutrients and other biomarkers via dynamic life microscopy approaches, such as Fluorescence Lifetime Imaging Microscopy (FLIM). As we heavily integrated into the research Core Facilities, education and training of MSc students, international collaborations and active lab research, we require Basic Funding to cover the costs of access to the Ghent University Core Facilities, training of the students, research and research-related travel.