Research Explorer

Project

Identification of proteases that activate membrane-bound transcription factors during mitochondrial retrograde regulation
Code
01CD06824
Duration
01 November 2024 → 30 April 2025
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Natural sciences
    • Cell signalling
    • Plant cell and molecular biology
    • Interactomics
    • Proteomics
  • Engineering and technology
    • Environmental plant biotechnology
Keywords
Proteolytic activation Arabidopsis thaliana Mitochondrial retrograde regulation
 
Project description
 Plants are threatened by adverse environments ((a)biotic stresses) in which they must continuously adapt to survive. Mitochondria play crucial roles in sensing and reporting stress signals to the nucleus. This project aims to identify protease(s) responsible for activation of membrane-bound transcription factors of a novel mitochondria-to-nucleus signaling pathway recently identified in the host lab, using state-of-the-art proteomics and chemical-biology approaches.