A novel role for Wnt/β-catenin signaling in primordial germ cells during Xenopus development

01 January 2013 → 31 December 2018
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Animal biology
    • Genetics
  • Agricultural and food sciences
    • Veterinary medicine
signaling embryonic development germ cells Xenopus
Project description

During embryonic development primordial germ cells (precursors of the gametes) actively migrate towards the gonads. During their formation and migration they are exposed to several of the signaling factors present in the embryo. Here we want to determine how one of these signaling factors, i.e. Wnt, affects the formation and behavior of these primordial germ cells in the Xenopus model.