Project

Glycomarker in perfusate for the prediction of liver primary non function

Acronym
Glycomarker PNF
Duration
01 October 2015 → 31 August 2017
Funding
Regional and community funding: Industrial Research Fund
Research disciplines
  • Medical and health sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other basic sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other clinical sciences
    • Other health sciences
    • Nursing
    • Other paramedical sciences
    • Laboratory medicine
    • Palliative care and end-of-life care
    • Regenerative medicine
    • Other translational sciences
    • Other medical and health sciences
Keywords
liver
 
Project description

Primary non-function (PNF) of a liver after liver transplantation is a complete absence of liver function immediately after liver transplantation. It occurs in 3-8% of liver transplants and is a medical urgency that requires an urgent liver transplant within 24-48h. PNF is related to the quality of the donor liver. Unfortunately, there are no good biomarkers to evaluate the quality of the donor liver. We propose an alternative approach to estimate delivery quality. The aim of this project is to make the transition from a proof of concept of the glycomarker for PNF to a biomarker that can be implemented in routine clinical practice.