Study of ubiquitination of the key proteins in the jasmonate signal transduction cascades of the model plant Arabidopsis thaliana

01 January 2012 → 31 December 2017
Research Foundation - Flanders (FWO)
Research disciplines
  • Natural sciences
    • Regulation of metabolism
    • Cell signaling
    • Posttranslational modifications
    • Plant cell and molecular biology
    • Plant immunology
arabidopsis Jasmonates ubiquitination E3-ligases
Project description

We will study E3 Ubiquitin ligases from the model plant Arabidopsis thaliana that are putatively involved in jasmonate signalling. We aim to (1) identify their actual substrates, (2) acquire mechanistic insight in how they are regulated themselves,and interact and ubiquitinate these targets, and (3) phenotypically characterise Arabidopsis plants with altered expression in these E3 Ub ligases to establish their precise role at the whole plant level.