Project

A precision medicin approach for canine degenerative myelopathy combining genetic and epigenetic alterations

Code
01CD4023
Duration
01 September 2023 → 30 April 2024
Funding
Regional and community funding: Special Research Fund
Research disciplines
  • Agricultural and food sciences
    • Veterinary genetics
    • Veterinary neurology
Keywords
(epi)genetics degenerative myelopathy Precision medicine
 
Project description

This research project aims to introduce precision medicine and epigenetics research in the canine neurogenetics field. Practically, canine degenerative myelopathy will be studied with MDB-seq to identify differentially methylated regions associated with disease progression. This will be followed by the writing of a general statistical analysis framework in R that accurately predicts clinical age of onset for this disorder.