Code
3F015714
Duration
01 October 2014 → 30 September 2018
Funding
Regional and community funding: Special Research Fund, Research Foundation - Flanders (FWO)
Promotor
Fellow
Research disciplines
-
Medical and health sciences
- Immunology
- Morphological sciences
- Oncology
- Physiology
- Immunology
- Morphological sciences
- Oncology
- Physiology
- Immunology
- Morphological sciences
- Oncology
- Physiology
Keywords
ubiquitination
signal transduction
Project description
CYLD plays a key role in immunity and inflammation by negatively regulating NF-κB and JNK signaling pathways, which leads to the activation of pro-inflammatory gene expression. In this project we will study the role of posttranslational modifications of CYLD in TCR stimulated cells.