The β-CUBE is a cutting-edge, high-performance preclinical PET (Positron Emission Tomography) imager designed for small animal imaging, primarily used for mice and rats. It achieves sub-millimeter resolution thanks to a combination of advanced technologies, including:

• Monolithic scintillators: These are used to detect gamma photons with high efficiency and precision.
• Photon counting technology: This allows for highly accurate measurement of photon events at a granular level.
• GPU-based event positioning: Utilizes the computational power of GPUs to accurately position events in space, improving image quality and reducing noise.
• Iterative image reconstruction: Enhances the resolution and clarity of images by iteratively refining the image from raw data.

The β-CUBE features a 5-ring configuration that ensures best-in-class sensitivity and is well-suited for whole-body imaging of small animals, even at high count rates. This setup makes it possible to obtain high-quality PET scans of mice and rats, which is crucial for preclinical research such as drug development and disease modeling.

In addition to its imaging capabilities, the β-CUBE is equipped with in-house hardware that supports dynamic and gated studies, allowing for real-time imaging during physiological processes like heartbeats or respiratory cycles.

The system also includes intuitive, wireless acquisition software, which simplifies the imaging process, making it user-friendly and easy to operate. The β-CUBE is designed to be modular and works seamlessly with other imaging systems like the γ-CUBE (SPECT) and X-CUBE (CT), enabling multimodal imaging. This integration allows researchers to combine different imaging techniques for a comprehensive view of biological processes, enhancing the depth and accuracy of their studies.