The Nikon Eclipse Ni-E is an upright microscope designed for advanced applications in life sciences such as cell biology, neurobiology, histology, and molecular biology. The system combines full motorization with excellent optical performance, providing maximum control, reproducibility, and ease of use for complex microscopic analyses.

The Ni-E features a fully motorized platform, including:

• Motorized Z-focus for precise focusing

• Motorized objective nosepiece for automatic switching between objectives

• Motorized universal condenser that automatically adjusts to the selected observation technique

• Motorized ND filter wheels and fluorescence components for optimized illumination and image quality

Its optical system utilizes Nikon’s CFI Plan Apochromat λ objectives with Nano Crystal Coat, delivering superior image resolution, high contrast, and minimal chromatic aberration—essential for high-quality imaging in fluorescence and other advanced techniques.

Thanks to the automatic observation mode, users can switch between techniques with the push of a button, including:

• Brightfield

• Darkfield

• Phase contrast

• Differential Interference Contrast (DIC)

• Fluorescence microscopy

Operation is handled via an intuitive DS-L3 touchscreen controller, allowing quick adjustments of settings and image capture. Additionally, the Ni-E is compatible with Nikon’s imaging analysis tools and expandable with confocal systems, photoactivation units, and high-speed shutters.

With its modular design and high level of automation, the Nikon Eclipse Ni-E is particularly suited for research requiring precision, speed, and reproducibility—from routine imaging to advanced live-cell analysis.