Infrastructure

Seahorse XFe96 Analyzer S7800B

Type
Equipment
Code
APP/00022
Date of commissioning
01 December 2019 → …
Research disciplines
  • Natural sciences
    • Molecular and cell biology not elsewhere classified
  • Medical and health sciences
    • Single-cell data analysis
    • Molecular and cell biology not elsewhere classified
    • Cell physiology
Keywords
OCR metabolic assay PER single-cell analysis cell death mitochondrial respiration ECAR
Brand Name/manufacturer
Agilent Technologies Belgium
Other information
 
Description

This Agilent Seahorse analyzer measures and reports the oxygen consumption rate (OCR), proton efflux rate (PER) or extracellular acidification rate (ECAR), as well as ATP production rates of live cells in a 96-well format. This analyzer features excellent OCR precision at low rates, verified instrument performance, optimized temperature control, and is automation enabled.

OCR, PER, and ATP production rates are critical measurements of energy metabolism and vital indicators of mitochondrial health, toxicity, glycolysis, and overall cellular (dys)function. Together, these measurements provide a systems-level view of cellular metabolic function in cultured cells and ex vivo samples.