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Researcher
Yves Dondelinger
Profile
Projects
Publications
Activities
Awards & Distinctions
26
Results
2023
NINJ1 is activated by cell swelling to regulate plasma membrane permeabilization during regulated necrosis
Yves Dondelinger
Dario Priem
Jon Huyghe
Tom Delanghe
Peter Vandenabeele
Mathieu Bertrand
A1
Journal Article
in
CELL DEATH & DISEASE
2023
RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD
Hannelore Van Eeckhoutte
Chantal Donovan
Richard Y. Kim
Thomas M. Conlon
Meshal Ansari
Haroon Khan
Ranjith Jayaraman
Nicole G. Hansbro
Yves Dondelinger
Tom Delanghe
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2023
2022
Phosphorylation of RIPK1 serine 25 mediates IKK dependent control of extrinsic cell death in T cells
Sam Blanchett
Yves Dondelinger
Alessandro Barbarulo
Mathieu Bertrand
Benedict Seddon
A1
Journal Article
in
FRONTIERS IN IMMUNOLOGY
2022
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
Charlotte Rigauts
Juliana Aizawa
Steven Taylor
Geraint B. Rogers
Matthias Govaerts
Paul Cos
Lisa Ostyn
Sarah Sims
Eva Vandeplassche
Mozes Sze
et al.
A1
Journal Article
in
EUROPEAN RESPIRATORY JOURNAL
2022
The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach
Pauline Puylaert
Isabelle Coornaert
Cedric H. G. Neutel
Yves Dondelinger
Tom Delanghe
Mathieu Bertrand
Pieter-Jan Guns
Guido R. Y. De Meyer
Wim Martinet
A1
Journal Article
in
BIOMEDICINES
2022
2021
Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor
Tom Delanghe
Jon Huyghe
Seungheon Lee
Dario Priem
Samya Van Coillie
Barbara Gilbert
Sze Men Choi
Peter Vandenabeele
Alexei Degterev
Gregory D. Cuny
et al.
A1
Journal Article
in
CELL DEATH & DISEASE
2021
Unraveling the role of RIPK1 phosphorylation in TNF-mediated cell death and inflammation
Tom Delanghe
Mathieu Bertrand
Yves Dondelinger
Dissertation
2021
2020
RIPK1 kinase-dependent death : a symphony of phosphorylation events
Tom Delanghe
Yves Dondelinger
Mathieu Bertrand
A1
Journal Article
in
TRENDS IN CELL BIOLOGY
2020
Respiratory Syncytial Virus infection promotes necroptosis and HMGB1 release by airway epithelial cells
Jennifer Simpson
Zhixuan Loh
Md Ashik Ullah
Jason P Lynch
Rhiannon B. Werder
Natasha Collinson
Vivian Zhang
Yves Dondelinger
Mathieu Bertrand
Mark L. Everard
et al.
A1
Journal Article
in
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2020
2019
Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
Yves Dondelinger
Tom Delanghe
Dario Priem
Meghan A Wynosky-Dolfi
Daniel Sorobetea
Diego Rojas Rivera
Piero Giansanti
Ria Roelandt
Julia Gropengiesser
Klaus Ruckdeschel
et al.
A1
Journal Article
in
NATURE COMMUNICATIONS
2019
2018
MK2 puts an additional brake on RIPK1 cytotoxic potential
Yves Dondelinger
Tom Delanghe
Mathieu Bertrand
Editorial material
2018
Monitoring RIPK1 phosphorylation in the TNFR1 signaling complex
Dario Priem
Yves Dondelinger
Mathieu Bertrand
Bookchapter
in
Programmed necrosis : methods and protocols
2018
N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis
Yann Estornes
Yves Dondelinger
Kathrin Weber
Inge Bruggeman
Adam Peall
Marion MacFarlane
Serge Lebecque
Peter Vandenabeele
Mathieu Bertrand
A1
Journal Article
in
CELL DEATH & DISEASE
2018
2017
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death
Yves Dondelinger
Tom Delanghe
Diego Rojas Rivera
Dario Priem
Tinneke Delvaeye
Inge Bruggeman
Franky Van Herreweghe
Peter Vandenabeele
Mathieu Bertrand
A1
Journal Article
in
NATURE CELL BIOLOGY
2017
2016
A real-time fluorometric method for the simultaneous detection of cell death type and rate
Sasker Grootjans
Behrouz Hassannia
Iris Delrue
Vera Goossens
Bartosz Wiernicki
Yves Dondelinger
Mathieu Bertrand
Dmitri Krysko
Marnik Vuylsteke
Peter Vandenabeele
et al.
A1
Journal Article
in
NATURE PROTOCOLS
2016
An evolutionary perspective on the necroptotic pathway
Yves Dondelinger
Paco Hulpiau
Yvan Saeys
Mathieu Bertrand
Peter Vandenabeele
A1
Journal Article
in
TRENDS IN CELL BIOLOGY
2016
CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3
Jinho Seo
Eun-Woo Lee
Hyerim Sung
Daehyeon Seong
Yves Dondelinger
Jihye Shin
Manhyung Jeong
Hae-Kyung Lee
Jung-Hoon Kim
Su Yeon Han
et al.
A1
Journal Article
in
NATURE CELL BIOLOGY
2016
Poly-ubiquitination in TNFR1-mediated necroptosis
Yves Dondelinger
Maurice Darding
Mathieu Bertrand
Henning Walczak
A1
Journal Article
in
CELLULAR AND MOLECULAR LIFE SCIENCES
2016
Regulation of RIPK1's cell death function by phosphorylation
Yves Dondelinger
Peter Vandenabeele
Mathieu Bertrand
Editorial material
2016
2015
NF-κB-independent role of IKKα/IKKβ in preventing RIPK1 kinase-dependent apoptotic and necroptotic cell death during TNF signaling
Yves Dondelinger
Sandrine Jouan-Lanhouet
Tatyana Divert
Emilie Theatre
John Bertin
Peter J Gough
Piero Giansanti
Albert JR Heck
Emmanuel Dejardin
Peter Vandenabeele
et al.
A1
Journal Article
in
MOLECULAR CELL
2015
Unraveling the molecular mechanisms of RIPK1-mediated cell death
Yves Dondelinger
Peter Vandenabeele
Mathieu Bertrand
Dissertation
2015
2014
Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
Quinten Remijsen
Vera Goossens
Sasker Grootjans
C Van den Haute
Nele Vanlangenakker
Yves Dondelinger
Ria Roelandt
Inge Bruggeman
Amanda Gonçalves
Mathieu Bertrand
et al.
A1
Journal Article
in
CELL DEATH & DISEASE
2014
MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates
Yves Dondelinger
Wim Declercq
Sylvie Montessuit
Ria Roelandt
Amanda Gonçalves
Inge Bruggeman
Paco Hulpiau
Kathrin Weber
Clark A Sehon
Robert W Marquis
et al.
A1
Journal Article
in
CELL REPORTS
2014
2013
Determination of apoptotic and necrotic cell death in vitro and in vivo
Tom Vanden Berghe
Sasker Grootjans
Vera Goossens
Yves Dondelinger
Dmitri Krysko
Nozomi Takahashi
Peter Vandenabeele
A1
Journal Article
in
METHODS
2013
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
Yves Dondelinger
Miguel Aguileta
Vera Goossens
Christel Dubuisson
Sasker Grootjans
E Dejardin
Peter Vandenabeele
Mathieu Bertrand
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
2013
2012
Intermediate domain of receptor-interacting protein kinase 1 (RIPK1) determines switch between necroptosis and RIPK1 kinase-dependent apoptosis
Linde Duprez
Mathieu Bertrand
Tom Vanden Berghe
Yves Dondelinger
Nele Festjens
Peter Vandenabeele
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2012