Research Explorer

Your browser does not support JavaScript or JavaScript is not enabled. Without JavaScript some functions of this webapplication may be disabled or cause error messages. To enable JavaScript, please consult the manual of your browser or contact your system administrator.

Researcher

Yves Depetter

Awards & Distinctions

9 Results

2020

Expedient synthesis of lupulones and their derivatization to 2,8-7H-dihydrochromen-7-ones

Lena DecuyperGurkirat KaurCharlotte VersyckEline BlondeelYves DepetterKristof Van HeckeMatthias D'hooghe

A1 Journal Article in CHEMISTRYOPEN

2019

Selective pharmacological inhibitors of HDAC6 reveal biochemical activity but functional tolerance in cancer models

Yves DepetterSilke GeursRob De VreeseSophie GoethalsElien VandoornAlien LaevensJonas SteenbruggeEvelyne MeyerPascal de TullioMarc Bracke et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Synthesis of indoline‐based benzhydroxamic acids as potential HDAC6 inhibitors

Yves DepetterSilke GeursJorick FranceusDamijan KnezTom DesmetKarolien De BosscherOlivier De WeverStanislav GobecMatthias D'hooghe

A1 Journal Article in CHEMISTRYSELECT

Synthesis of selective HDAC6 inhibitors and their evaluation in cancer models

Yves DepetterMatthias D'hoogheOlivier De Wever

2018

Assessment of the trifluoromethyl ketone functionality as an alternative zinc-binding group for selective HDAC6 inhibition

Yves DepetterSilke GeursFlore Vanden BusscheRob De VreeseJorick FranceusTom DesmetOlivier De WeverMatthias D'hooghe

A1 Journal Article in MEDCHEMCOMM

2017

Synthesis of potent and selective HDAC6 inhibitors bearing a cyclohexane- or cycloheptane-annulated 1,5-benzothiazepine scaffold

Rob De VreeseLisa GalleYves DepetterJorick FranceusTom DesmetKristof Van HeckeVeronick BenoyLudo Van Den BoschMatthias D'hooghe

A1 Journal Article in CHEMISTRY-A EUROPEAN JOURNAL

2016

Synthesis and SAR assessment of novel Tubathian analogs in the pursuit of potent and selective HDAC6 inhibitors

Rob De VreeseYves DepetterTom VerhaegheTom DesmetVeronick BenoyWanda HaeckLudo Van Den BoschMatthias D'hooghe

A1 Journal Article in ORGANIC & BIOMOLECULAR CHEMISTRY

2015

Expedient stereoselective synthesis of new dihydropyrano- and dihydrofuranonaphthoquinones

Tuyet Anh Dang ThiYves DepetterKaren MolletHoang Thi PhuongDoan Vu NgocChinh Pham TheHa Thanh NguyenThu Ha Nguyen ThiHung Huy NguyenMatthias D'hooghe et al.

A1 Journal Article in TETRAHEDRON LETTERS

Synthesis and anticancer properties of new (dihydro)pyranonaphthoquinones and their epoxy analogs

Anh Dang Thi TuyetHa Vu Thi ThuThi Phuong HoangHa Nguyen ThanhPham The ChinhVu Duc CuongYves DepetterVan Nguyen TuyenMatthias D'hooghe

A1 Journal Article in BIOORGANIC & MEDICINAL CHEMISTRY LETTERS