Research Explorer

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Researcher

Yong Chen

Awards & Distinctions

6 Results

2023

Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue

Zifu ZhongYong ChenKim DeswarteHeleen LauwersEmily De LombaerdeXiaole CuiSimon Van HerckTingting YeMark GontsarikStefan Lienenklaus et al.

A1 Journal Article in ADVANCED HEALTHCARE MATERIALS

Lipid nanoparticle encapsulation empowers poly(I:C) to activate cytoplasmic RLRs and thereby increases its adjuvanticity

Alexander LamootSonia JangraGabriel LaghlaliPrajakta WarangLauren A. ChangSeok‐Chan ParkGagandeep SinghKim DeswarteZifu ZhongBenoit Louage et al.

A1 Journal Article in SMALL

Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions

Helena BraetPeter-Paul FransenYong ChenSimon Van HerckRemco MariënValérie VanhoorneWim CeelenAnnemieke MadderSteven BalletRichard Hoogenboom et al.

A1 Journal Article in JOURNAL OF CONTROLLED RELEASE

Successful batch and continuous lyophilization of mRNA LNP formulations depend on cryoprotectants and ionizable lipids

Alexander LamootJoris LammensEmily De LombaerdeZifu ZhongMark GontsarikYong ChenThomas De BeerBruno De Geest

A1 Journal Article in BIOMATERIALS SCIENCE

2021

Lipid-polyglutamate nanoparticle vaccine platform

Dorien Van LysebettenAlessio MalfantiKim DeswarteKaloian KoynovBianka GolbaTingting YeZifu ZhongSabah KasmiAlexander LamootYong Chen et al.

A1 Journal Article in ACS APPLIED MATERIALS & INTERFACES

2020

Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles

Bi WangSimon Van HerckYong ChenXiangyang BaiZifu ZhongKim DeswarteBart LambrechtNiek SandersStefan LienenklausHans W. Scheeren et al.

A1 Journal Article in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY