Research Explorer

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Researcher

Xavier Verhelst

Awards & Distinctions

220 Results

2025

Glycomics as prognostic biomarkers of hepatocellular carcinoma : a systematic review

Nicky SomersEmma ButayeLorenz GrossarNele PauwelsAnja GeertsSarah RaevensSander LefereLindsey DevisscherLeander MeurisNico Callewaert et al.

A1 Journal Article in ONCOLOGY LETTERS

2024

Adipose tissue insulin resistance correlates with disease severity in pediatric metabolic dysfunction-associated steatotic liver disease : a prospective cohort study

Anneleen HeldensEllen DupontLindsey DevisscherMaarten BuytaertXavier VerhelstSarah RaevensHans Van VlierbergheAnja GeertsRuth De BruyneSander Lefere

A1 Journal Article in JOURNAL OF PEDIATRICS

External validation of the IAIHG autoimmune hepatitis response criteria in a multicentric real-world cohort

Lorenz GrossarSarah RaevensChristophe Van SteenkisteIsabelle ColleCharlotte De VlooHans OrlentJeoffrey SchoutenMarie GallantAnnelien Van DriesscheSander Lefere et al.

A1 Journal Article in JHEP REPORTS

Importance of sinonasal evaluation before transplantation : systematic review with meta-analysis and proposal of a screening protocol

Casper De VrieseConstantijn BogaertSteven Van LaeckeAnke DelieXavier VerhelstTessa KerreThibaut Van Zele

A2 Journal Article in EXPERIMENTAL AND CLINICAL TRANSPLANTATION

Maternal liver-related symptoms during pregnancy in primary sclerosing cholangitis

Jeremy S NayagamTobias J WeismüllerPiotr MilkiewiczKarolina M WronkaEmil BikChristoph SchrammKatja FuesselTaotao ZhouJohannes ChangMartti Färkkilä et al.

A1 Journal Article in JHEP REPORTS

Optimizing the use of biologics in psoriasis : role of therapeutic drug monitoring and serum biomarkers

Lisa SchotsJo LambertLynda GrineXavier Verhelst

Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis

Kevin De MuynckLander HeyerickFederico Francesco De PontiBart VanderborghtTim MeeseSanne Van CampenhoutLeen BaudonckEva GijbelsPedro M. RodriguesJesus M. Banales et al.

A1 Journal Article in HEPATOLOGY

Recurrent rejections after liver transplantation for hepatocellular carcinoma with stem cell features in an adult patient

Simon MeganckSarah RaevensKymentie FerdinandeXavier VerhelstAnne HoorensHelena DegrooteAnja GeertsHans Van Vlierberghe

A1 Journal Article in ACTA CLINICA BELGICA

Systematic review : glycomics as diagnostic markers for hepatocellular carcinoma

Emma ButayeNicky SomersLorenz GrossarNele PauwelsSander LefereLindsey DevisscherSarah RaevensAnja GeertsLeander MeurisNico Callewaert et al.

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

The association of ultra‐processed food intake with adolescent metabolic dysfunction‐associated steatotic liver disease in the NHANES

Maarten BuytaertDimitri DeclercqFleur DepoorterZerlina CosijnLindsey DevisscherSarah RaevensXavier VerhelstHans Van VlierbergheAnja GeertsRuth De Bruyne et al.

A1 Journal Article in PEDIATRIC OBESITY

Ultra-processed food intake does not correlate with pediatric MASLD in the National Health and Nutrition Examination Survey

Maarten BuytaertDimitri DeclercqFleur DepoorterZerlina CosijnLindsey DevisscherAnja GeertsXavier VerhelstHans Van VlierbergheSarah RaevensRuth De Bruyne et al.

2023

A remarkable presentation of a massive Budd-Chiari syndrome

Kymentie FerdinandeHelena DegrooteAnja GeertsHans Van VlierbergheXavier VerhelstSarah Raevens

Editorial material

An unusual cause of portal hypertension

Kymentie FerdinandeThibaud LamiroyAnne HoorensXavier VerhelstHelena DegrooteSarah RaevensHans Van VlierbergheAnja Geerts

Editorial material

Glycomics-based serum markers as reliable tool for assessment of viral response after treatment with direct-acting antiviral drugs in hepatitis C virus infection

Nicky SomersElisabeth VandekerckhoveAnja GeertsHelena DegrooteSander LefereLindsey DevisscherLeander MeurisNico CallewaertHans Van VlierbergheXavier Verhelst

A1 Journal Article in ACTA CLINICA BELGICA

Impact on follow-up strategies in patients with primary sclerosing cholangitis

Annika BergquistTobias J. WeismuellerCynthia LevyChristian RuppDeepak JoshiJeremy Shanika NayagamAldo J. Montano-LozaEllina LytvyakEwa WunschPiotr Milkiewicz et al.

A1 Journal Article in LIVER INTERNATIONAL

Kupffer cells contested as early drivers in the pathogenesis of primary sclerosing cholangitis

Kevin De MuynckBart VanderborghtFederico Francesco De PontiEva GijbelsSophie Van WeldenMartin GuilliamsCharlotte ScottAlain BeschinMathieu VinkenSander Lefere et al.

A1 Journal Article in AMERICAN JOURNAL OF PATHOLOGY

Liver transplantation for porto-sinusoidal vascular liver disorder : long-term outcome

Marta MagazHeloïse Giudicelli-LettOana Nicoară-FarcăuNeil RajoriyaAshish GoelKarlien RaymenantsSophie HillaireGonzalo CrespoLuis TéllezLaure Elkrief et al.

A1 Journal Article in TRANSPLANTATION

Meta-analysis : the impact of light-to-moderate alcohol consumption on progressive non-alcoholic fatty liver disease

Louise MaghermanRobbe Van ParysNele PauwelsXavier VerhelstLindsey DevisscherHans Van VlierbergheAnja GeertsSander Lefere

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Optimizing therapy in primary biliary cholangitis : alkaline phosphatase at six months identifies one-year non-responders and predicts survival

C Fiorella Murillo PerezStephanie IoannouIman HassanallyPalak J TrivediChristophe CorpechotAdriaan J van der MeerWillem J LammersPier Maria BattezzatiKeith D LindorFrederik Nevens et al.

A1 Journal Article in LIVER INTERNATIONAL

Patients hospitalized with alcohol-related liver disease and prior bariatric surgery are more prone to develop acute-on-chronic liver failure

Louis OnghenaYves Van NieuwenhoveLaurissa DemeulenaereLindsey DevisscherXavier VerhelstHelena DegrooteSarah RaevensHans Van VlierbergheSander LefereAnja Geerts

A1 Journal Article in LIVER INTERNATIONAL

Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis : ENHANCE, a phase 3, randomized, placebo-controlled study

Gideon M HirschfieldMitchell L ShiffmanAliya GulamhuseinKris V KowdleyJohn M VierlingCynthia LevyAndreas E KremerEhud ZigmondPietro AndreoneStuart C Gordon et al.

A1 Journal Article in HEPATOLOGY

Serological response and breakthrough infection after COVID-19 vaccination in patients with cirrhosis and post-liver transplant

Gautam MehtaAntonio RivaMaria Pilar BallesterEva UsonMontserrat PujadasÂngela Carvalho-GomesIvan SahucoAriadna BonoFederico D'AmicoRaffaela Viganò et al.

A1 Journal Article in HEPATOLOGY COMMUNICATIONS

Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma

Bart VanderborghtKevin De MuynckEva GijbelsSander LefereCharlotte ScottMartin GuilliamsAlain BeschinMathieu VinkenXavier VerhelstAnja Geerts et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF CANCER

Unraveling monocyte/macrophage heterogeneity in the disturbed gut-liver axis in primary sclerosing cholangitis and ulcerative colitis

Kevin De MuynckLindsey DevisscherXavier Verhelst

Ursodeoxycholic acid treatment-induced GLOBE score changes are associated with liver transplantation-free survival in patients with primary biliary cholangitis

Rozanne C de VeerMaria C van HooffChristophe CorpechotDouglas ThorburnPietro InvernizziWillem J LammersHarry L A JanssenPier M BattezzatiFrederik NevensKeith D Lindor et al.

A1 Journal Article in AMERICAN JOURNAL OF GASTROENTEROLOGY

2022

A multicentric study to estimate mortality and graft loss risk after liver transplantation (LT) in patients with recurrent primary biliary cholangitis (PBC)

Aldo J. Montano-LozaThierry BerneyChristian TosoGiulia MaginiGideon HirschfieldBettina HansenAndrew L. MasonMaryam EbadiFrederik NevensNatalie Van den Ende et al.

Adipose tissue insulin resistance is a determinant of disease severity in pediatric nonalcoholic fatty liver disease

Anneleen HeldensEllen DupontLindsey DevisscherAnja GeertsRuth De BruyneXavier VerhelstHans Van VlierbergheSander Lefere

Aminotransferases during treatment predict long-term survival in patients with autoimmune hepatitis type 1 : a landmark analysis

Maaike BiewengaXavier VerhelstMartine Baven-PronkHein PutterAad van den BergIsabelle ColleJeoffrey SchoutenFilip SermonChristophe Van SteenkisteHans Van Vlierberghe et al.

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Different models to predict the risk of recurrent hepatocellular carcinoma in the setting of liver transplantation

Helena DegrooteAnja GeertsXavier VerhelstHans Van Vlierberghe

A1 Journal Article in CANCERS

Enhanced liver fibrosis score correlates with transient elastography in patients with treated autoimmune hepatitis

Anna StoelingaElsemieke de VriesMaarten TushuizenAlbert StattermayerXavier VerhelstBart Van Hoek

Glycomics-based serum marker as reliable tool for assessment of viral response after treatment with direct-acting antiviral drugs in hepatitis C virus infection

Nicky SomersElisabeth VandekerckhoveAnja GeertsHelena DegrooteSander LefereLindsey DevisscherLeander MeurisNico CallewaertHans Van VlierbergheXavier Verhelst

Illness cognitions and health-related quality of life in liver transplant patients related to length of stay, comorbidities and complications

Louis OnghenaFrederik BerrevoetAude VanlanderHans Van VlierbergheXavier VerhelstEric HosteCarine Poppe

A1 Journal Article in QUALITY OF LIFE RESEARCH

Intensive lifestyle management improves steatosis and fibrosis in pediatric non-alcoholic fatty liver disease

Sander LefereEllen DupontAnn De GuchtenaereStephanie Van BiervlietSaskia Vande VeldeXavier VerhelstLindsey DevisscherHans Van VlierbergheAnja GeertsRuth De Bruyne

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Liver-transplant-free survival according to alkaline phosphatase and GLOBE score in patients with primary biliary cholangitis treated with ursodeoxycholic acid

Rozanne C. de VeerMaren H. HarmsChristophe CorpechotDouglas ThorburnPietro InvernizziHarry L. A. JanssenPier M. BattezzatiFrederik NevensKeith D. LindorAnnarosa Floreani et al.

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Long-term obeticholic acid (OCA) for primary biliary cholangitis (PBC) in a clinical trial improved event free survival (death, liver transplant and hepatic decompensation) compared to external controls from the GLOBAL PBC real-world database

Carla Fiorella Murillo PerezFemi AdekunleTracy MayneElizabeth MalechaErik NessAdriaan Van der MeerWillem LammersPalak TrivediPier Maria BattezzatiFrederik Nevens et al.

Long-term obeticholic acid (OCA) for primary biliary cholangitis (PBC) in a clinical trial improved event free survival (death, liver transplant and hepatic decompensation) compared to external controls from the global PBC real-world database

Fiorella Murillo PerezFemi AdekunleTracy MayneElizabeth MalechaEric NessAdriaan J. Van der MeerWillem J. LammersPalak J. TrivediPier Maria BattezzatiFrederik Nevens et al.

Long-term obeticholic acid for primary biliary cholangitis in a clinical trial improved event-free survival (death, liver transplantation, and hepatic decompensation) compared with external controls from the GLOBAL PBC real-world database

C. F. Murillo PerezH. FisherS. HiuD. KareithiF. AdekunleT. MayneE. MalechaE. NessA. J. Van der MeerW. J. Lammers et al.

Maternal and perinatal risk factors for pediatric nonalcoholic fatty liver disease : a systematic review

Ilya QuerterNele PauwelsRuth De BruyneEllen DupontXavier VerhelstLindsey DevisscherHans Van VlierbergheAnja GeertsSander Lefere

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Maternal liver outcomes of pregnancy in patients with primary sclerosing cholangitis

Jeremy NayagamTobias J. WeismuellerPiotr MilkiewiczKarolina WronkaEmil BikChristoph SchrammKatja FuesselTaotao ZhouJohannes ChangMartti Farkkila et al.

Neurometabolic and gliovascular changes in murine hepatic encephalopathy

Wouter ClaeysLien Van HoeckeAnja GeertsHans Van VlierbergheXavier VerhelstSander LefereHelena DegrooteGriet Van ImschootElien Van WonterghemRoosmarijn Vandenbroucke et al.

Patients with primary biliary cholangitis treated with long-term obeticholic acid in a trial-setting demonstrate better event-free survival outcomes than external controls from the global PBC and UK-PBC study groups

C. Fiorella Murillo PerezKris V. KowdleyHolly FisherShaun HiuFemi AdekunleTracy MayneElizabeth Smoot MalechaErik NessAdriaan J. van der MeerWillem J. Lammers et al.

Pretransplant alterations in serum protein glycosylation are associated to risk of hcc recurrence after liver transplantation and provide a potential prognostic biomarker : a proof-of-concept study

Xavier VerhelstHeleen EngelsAllison GeertsAude VanlanderLuis Abreu De CarvalhoHelena DegrooteLeander MeurisFrederik BerrevoetNico CallewaertHans Van Vlierberghe

Pretransplant changes in serum protein glycosylation relate to risk of HCC recurrence after liver transplantation and provide a potential prognostic biomarker : a proof-of-concept study

Xavier VerhelstHeleen EngelsAnja GeertsAude VanlanderLuis Abreu De CarvalhoHelena DegrooteLeander MeurisFrederik BerrevoetNico CallewaertHans Van Vlierberghe

Rare case of ascites several years after liver transplantation

Liesbeth DerooAnne HoorensXavier VerhelstHelena DegrooteHans Van VlierbergheAnja Geerts

Editorial material

Validation of a glycomics-based test associated with risk of HCC development in cirrhosis

Xavier VerhelstLeander MeurisRoos ColmanAnnelies Van HeckeAnja GeertsNico CallewaertHans Van Vlierberghe

Y-90 radioembolization versus drug-eluting bead chemoembolization for unresectable hepatocellular carcinoma : results from the TRACE phase II randomized controlled trial

Elisabeth DhondtBieke LambertLaurens HermieLynn HuyckPeter VanlangenhoveAnja GeertsXavier VerhelstMaridi AertsAude VanlanderFrederik Berrevoet et al.

A1 Journal Article in RADIOLOGY

Yttrium-90 radioembolization versus drug-eluting beads chemoembolization for unresectable hepatocellular carcinoma : results from the TRACE phase 2 randomized controlled trial

Elisabeth DhondtBieke LambertLaurens HermieLynn HuyckPeter VanlangenhoveAnja GeertsXavier VerhelstMaridi AertsAude VanlanderFrederik Berrevoet et al.

2021

Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models

Helena DegrooteSander LefereAstrid VandierendonckBart VanderborghtTim MeeseFilip Van NieuwerburghXavier VerhelstAnja GeertsHans Van VlierbergheLindsey Devisscher

A2 Journal Article in ONCOTARGET

Clinical features and evolution of bacterial infection-related acute-on-chronic liver failure

F WongS PianoV SinghM BartolettiR MaiwallC AlessandriaJ FernandezEC SoaresDJ KimSE Kim et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

Development and validation of a prognostic score for long-term transplant-free survival in autoimmune hepatitis type 1

Maaike BiewengaXavier VerhelstMartine A. M. C. Baven-PronkHein PutterAad P. van den BergKarin C. M. J. van NieuwkerkHenk R. van BuurenGerd BoumaYnte S. de BoerCedric Simoen et al.

A1 Journal Article in UNITED EUROPEAN GASTROENTEROLOGY JOURNAL

Diagnostic and prognostic scoring systems for autoimmune hepatitis : a review

Olivier DucazuHelena DegrooteAlbert GeertsAnne HoorensJ. SchoutenHans Van VlierbergheXavier Verhelst

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Early identification of insufficient biochemical response to ursodeoxycholic acid in patients with primary biliary cholangitis

Carla Fiorella Murillo PerezStephanie IoannouIman HassanallyPalak TrivediChristophe CorpechotAdriaan J. Van der MeerWillem J. LammersPier Maria BattezzatiKeith D. LindorFrederik Nevens et al.

Focal eosinophilic infiltration of the liver, benign or malignant?

Wouter ClaeysAnke DeliePeter SmeetsMarie-Angélique De ScheerderHelena DegrooteXavier VerhelstHans Van VlierbergheAnja Geerts

A2 Journal Article in CLINICAL CASE REPORTS

Health status of patients with autoimmune hepatitis is not affected by the SARS-CoV-2 outbreak in Flanders, Belgium

Xavier VerhelstNicky SomersAnja GeertsHelena DegrooteHans Van Vlierberghe

A1 Journal Article in JOURNAL OF HEPATOLOGY

Hepatitis C in two general practices in Flanders, Belgium : is there a need to reconsider current screening recommendations?

Ruth BottermanXavier VerhelstVeerle BuffelAnselme DereseThomas Van der PaeltGarence De VolderHans Van VlierberghePauline Boeckxstaens

A1 Journal Article in ACTA CLINICA BELGICA

Hepatobiliary malignancy surveillance strategies in primary sclerosing cholangitis associate with reduced mortality

Annika M. BergquistTobias WeismuellerCynthia LevyChristian RuppDeepak JoshiJeremy NayagamAldo J. Montano-LozaEllina LytvyakEwa WunschPiotr Milkiewicz et al.

Intensive lifestyle management improves steatosis and fibrosis in pediatric metabolic-associated fatty liver disease

Sander LefereEllen DupontAnn De GuchtenaereStephanie Van BiervlietSaskia Vande VeldeXavier VerhelstLindsey DevisscherHans Van VlierbergheAnja GeertsRuth De Bruyne

Liver transplant for porto-sinusoidal vascular disease (psvd) : long-term outcome

Marta MagazHeloise Giudicelli-LettOana Nicoara-FarcauNeil RajoriyaAshish GoelFrancois DurandLena SmetsKarlien RaymenantsSophie HillaireGonzalo Crespo et al.

Measurement of gamma glutamyl transferase to determine risk of liver transplantation or death in patients with primary biliary cholangitis

Alessio GerussiDavide Paolo BernasconiSarah Elisabeth O'DonnellWillem J. LammersHenk Van BuurenGideon HirschfieldHarry JanssenChristophe CorpechotAnna ReigAlbert Pares et al.

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

NOX1 inhibition attenuates the development of a pro‐tumorigenic environment in experimental hepatocellular carcinoma

Aster VandierendonckHelena DegrooteBart VanderborghtXavier VerhelstAnja GeertsLindsey DevisscherHans Van Vlierberghe

A1 Journal Article in JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Patients with primary biliary cholangitis treated with long-term obeticholic acid in a trial-setting demonstrate better transplant-free survival than external controls from the global PBC and UK-PBC study groups

Carla Fiorella Murillo PerezHolly FisherShaun HiuFemi AdekunleMartin BonacciTracy MayneElizabeth Smoot MalechaErik NessAdriaan J. Van der MeerWillem Lammers et al.

Serum glycomics 7 days after liver transplantation relate to graft loss 3 months after liver transplantation independently of early allograft dysfunction

Xavier VerhelstAnja GeertsRachel ColmanAude VanlanderLuis Filipe Abreu de CarvalhoRoberto TroisiFrederik BerrevoetXavier RogiersNadine CallewaertHans Van Vlierberghe et al.

Serum glycomics on postoperative day 7 are associated with graft loss within 3 months after liver transplantation regardless of early allograft dysfunction

Xavier VerhelstAnja GeertsRoos ColmanAude VanlanderHelena DegrooteLuis Abreu De CarvalhoLeander MeurisFrederik BerrevoetXavier RogiersNico Callewaert et al.

A1 Journal Article in TRANSPLANTATION

Simplified care-pathway selection for nonspecialist practice : the GLOBAL Primary Biliary Cholangitis Study Group Age, Bilirubin, Alkaline phosphatase risk assessment tool

CF Murillo PerezA GulamhuseinM CarbonePJ TrivediAJ van der MeerC CorpechotPM BattezzatiWJ LammersN CazzagonA Floreani et al.

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

The neurogliovascular unit in hepatic encephalopathy

Wouter ClaeysLien Van HoeckeSander LefereAnja GeertsXavier VerhelstHans Van VlierbergheHelena DegrooteLindsey DevisscherRoosmarijn VandenbrouckeChristophe Van Steenkiste

A1 Journal Article in JHEP REPORTS

The utility of biomarkers in prognosis assessment of patients with acute liver failure

Pauline De ClercqAnja GeertsHans Van VlierbergheXavier Verhelst

A1 Journal Article in HEPATOLOGY RESEARCH

2020

Bariatric surgery patients are at risk for alcoholic liver disease with need for liver transplantation

Sander LefereLenka StroobantXavier VerhelstAude VanlanderFrederik BerrevoetRoberto TroisiYves Van NieuwenhoveXavier RogiersHans Van VlierbergheAnja Geerts

A1 Journal Article in OBESITY SURGERY

Characterising normal patterns of alanine aminotransferase elevations in ursodeoxycholic acid-treated patients with primary biliary cholangitis

Antoine SioufiCarla Fiorella Murillo PerezFrederik NevensAliya F. GulamhuseinMarco CarbonePalak TrivediAdriaan J. Van der MeerChristophe CorpechotPier M. BattezzatiWillem J. Lammers et al.

Combination of sivelestat and N-acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen-induced liver injury

Sarah RaevensSanne Van CampenhoutPieter-Jan DebackerSander LefereXavier VerhelstAnja GeertsHans Van VlierbergheIsabelle ColleLindsey Devisscher

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

Effect of isoform-specific HIF-1α and HIF-2α antisense oligonucleotides on tumorigenesis, inflammation and fibrosis in a hepatocellular carcinoma mouse model

Bart VanderborghtKevin De MuynckSander LefereAnja GeertsHelena DegrooteXavier VerhelstHans Van VlierbergheLindsey Devisscher

A2 Journal Article in ONCOTARGET

Factors associated with progression and outcomes of early stage primary biliary cholangitis

Nikolaos K GatselisJorn C GoetKalliopi ZachouWillem J LammersHarry LA JanssenGideon HirschfieldChristophe CorpechotKeith D LindorPietro InvernizziMarlyn J Mayo et al.

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Goals of treatment for improved survival in primary biliary cholangitis : treatment target should be bilirubin within the normal range and normalization of alkaline phosphatase

Carla F. Murillo PerezMaren H. HarmsKeith D. LindorHenk R. van BuurenGideon M. HirschfieldChristophe CorpechotAdriaan J. van der MeerJordan J. FeldAliya GulamhuseinWillem J. Lammers et al.

A1 Journal Article in AMERICAN JOURNAL OF GASTROENTEROLOGY

Long-term impact of preventive UDCA therapy after transplantation for primary biliary cholangitis

Christophe CorpechotOlivier ChazouilleresPierre BelnouAldo J. Montano-LozaAndrew MasonMaryam EbadiDennis EurichSascha ChopraDietmar JacobChristoph Schramm et al.

A1 Journal Article in JOURNAL OF HEPATOLOGY

Myeloid IRE1a deletion alters hepatic macrophage phenotype and attenuates experimental non-alcoholic steatohepatitis-related hepatocellular carcinoma

Sanne Van CampenhoutLaurentijn TillemanSander LefereAstrid VandierendonckAnja GeertsXavier VerhelstFilip Van NieuwerburghHans Van VlierbergheLindsey Devisscher

Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model

Sanne Van CampenhoutLaurentijn TillemanSander LefereAster VandierendonckSarah RaevensXavier VerhelstAnja GeertsFilip Van NieuwerburghHans Van VlierbergheLindsey Devisscher

A1 Journal Article in METABOLISM-CLINICAL AND EXPERIMENTAL

Patients with chronic hepatitis C virus infection are at high risk of being lost to follow-up : focused interventions can increase linkage to care

Hannah KeymeulenHannah Van de VeldeHelena DegrooteAnja GeertsHans Van VlierbergheXavier Verhelst

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Protein glycosylation as a diagnostic and prognostic marker of chronic inflammatory gastrointestinal and liver diseases

Xavier VerhelstAna M DiasJean-Frederic ColombelSeverine VermeireHans Van VlierbergheNico CallewaertSalome S Pinho

A1 Journal Article in GASTROENTEROLOGY

Transarterial radioembolization versus drug-eluting beads chemoembolization for treatment of inoperable early and intermediate hepatocellular carcinoma : interim results of the randomized controlled TRACE trial

Bernard LambertEllie DhondtLaurens HermieXavier VerhelstLuc Defreyne

Up to 50% of portal vein thrombosis remains undiagnosed until liver transplantation

Josephine BertAnja GeertsAude VanlanderLUIS ABREU DE CARVALHOHelena DegrooteFrederik BerrevoetXavier RogiersHans Van VlierbergheXavier Verhelst

A1 Journal Article in CLINICAL TRANSPLANTATION

Vasomodulators and liver transplantation for portopulmonary hypertension : evidence from a systematic review and meta-analysis

Rebecca DerooEric TrepoTom HolvoetMichel De PauwAnja GeertsXavier VerhelstIsabelle ColleHans Van VlierbergheMichael B. FallonSarah Raevens

A1 Journal Article in HEPATOLOGY

2019

Angiopoietin-2 promotes pathological angiogenesis and is a therapeutic target in murine nonalcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

A1 Journal Article in HEPATOLOGY

Derivation of a machine learning model to predict clinical outcome in patients with primary biliary cholangitis

Jorn GoetSurain RobertsGideon HirschfieldPietro InvernizziMarco CarbonePalak TrivediChristophe CorpechotHarry LA JanssenRozanne de VeerWillem J Lammers et al.

Effects of age and sex of response to ursodeoxycholic arid and transplant-free survival in patients with primary biliary cholangitis

Angela C. CheungWillem J. LammersCarla F. Murillo PerezHenk R. van BuurenAliya GulamhuseinPalak J. TrivediKonstantinos N. LazaridisCyriel Y. PonsioenAnnarosa FloreaniGideon M. Hirschfield et al.

A1 Journal Article in CLINICAL GASTROENTEROLOGY AND HEPATOLOGY

Epidemiology and effects of bacterial infections in patients with cirrhosis worldwide

Salvatore PianoVirendra SinghPaolo CaraceniRakhi MaiwallCarlo AlessandriaJavier FernandezElza Cotrim SoaresDong Joon KimSung Eun KimMonica Marino et al.

A1 Journal Article in GASTROENTEROLOGY

Factors associated with recurrence of primary biliary cholangitis after liver transplantation and effects on graft and patient survival

Aldo J. Montano-LozaBettina E. HansenChristophe CorpechotDavide RoccarinaDouglas ThorburnPalak TrivediGideon HirschfieldPatrick McDowellRaoul PouponJerome Dumortier et al.

A1 Journal Article in GASTROENTEROLOGY

Fibrosis stage is an independent predictor of outcome in primary biliary cholangitis despite biochemical treatment response

Carla F. Murillo PerezGideon M. HirschfieldChristophe CorpechotAnnarosa FloreaniMarlyn J. MayoAdriaan van der MeerCyriel Y. PonsioenWillem J. LammersAlbert ParesPietro Invernizzi et al.

A1 Journal Article in ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Hepatitis C virus (HCV) prevalence estimation in the adult general population in Belgium : a meta-analysis

G. MuyldermansR. BielenRuth BottermanS. BourgeoisI ColleB. DeressaG. DevolderY. HorsmansV HutseN. Lanthier et al.

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Myeloid-specific IRE1 alpha deletion reduces tumour development in a non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model

Sanne Van CampenhoutSander LefereAster VandierendonckXavier VerhelstAnja GeertsHans Van VlierbergheLindsey Devisscher

Optimising trial design in late-stage primary biliary cholangitis : evaluating options for composite clinical endpoint studies

Carla Fiorella Murillo PerezWillem J LammersAnnarosa FloreaniChristophe CorpechotAdriaan Van der MeerAliya GulamhuseinCyriel PonsioenMarco CarboneMarlyn J MayoPietro Invernizzi et al.

Oral vasodilator treatment and liver transplantation for portopulmonary hypertension : systematic review and meta-analysis of hemodynamic response and prognosis

Rebecca DerooMichel De PauwEric TrepoTom HolvoetAnja GeertsXavier VerhelstIsabelle ColleHans Van VlierbergheSarah Raevens

Outcome of liver transplantation for hepatopulmonary syndrome : a Eurotransplant experience

Sarah RaevensXavier RogiersAnja GeertsXavier VerhelstUndine SamuelMarieke van RosmalenGabriela BerlakovichJean DelwaideOlivier DetryFrank Lehner et al.

A1 Journal Article in EUROPEAN RESPIRATORY JOURNAL

Portal vein thrombosis in patients on the waiting list for liver transplantation : a single center cohort study

Josephine BertAnja GeertsAude VanlanderLUIS ABREU DE CARVALHOFrederik BerrevoetRoberto TroisiXavier RogiersHans Van VlierbergheXavier Verhelst

Portal vein thrombosis on the waiting list for liver transplantation : a single center cohort study

Josephine BertAnja GeertsAude VanlanderLUIS ABREU DE CARVALHOFrederik BerrevoetRoberto TroisiXavier RogiersHans Van VlierbergheXavier Verhelst

Preventive administration of ursodeoxycholic acid after liver transplantation for primary biliary cholangitis prevents disease recurrence and prolongs graft survival

C. CorpechotO. ChazouilleresA. J. Montano-LozaA. L. MasonM. EbadiD. EurichS. ChopraD. JacobC. SchrammM. Sterneck et al.

Screening for hepatitis C viral infection in a non-urban primary care facility in Flanders

Xavier VerhelstG. DevolderM. De WildeL. GoderisA. De BelEmiel SpillebeenAnja GeertsAnselme DereseHans Van Vlierberghe

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Second-line therapy is indicated in ursodeoxycholic acid-treated patients with primary biliary cholangitis and high alkaline phosphatase despite a complete globe-score response

Rozanne de VeerMaren H HarmsChristophe CorpechotWillem J LammersDouglas ThorburnPietro InvernizziHarry LA JanssenPier Maria BattezzatiFrederik NevensKeith D Lindor et al.

Serum glycomics on postoperative day 7 are associated with graft loss 3 months after liver transplantation

Xavier VerhelstAnja GeertsRoos ColmanAude VanlanderLUIS ABREU DE CARVALHOFrederik BerrevoetRoberto TroisiXavier RogiersNico CallewaertHans Van Vlierberghe

The potential of glycomics as prognostic biomarkers in liver disease and liver transplantation

Xavier VerhelstAnja GeertsNico CallewaertHans Van Vlierberghe

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Update on liver transplantation for cholangiocarcinoma : a review of the recent literature

Stéphanie LaurentXavier VerhelstAnja GeertsKaren GeboesMarc De ManRoberto TroisiAude VanlanderXavier RogiersFrederik BerrevoetHans Van Vlierberghe

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Ursodeoxycholic acid treatment-induced globe score changes are associated with liver transplantation-free survival in patients with primary biliary cholangitis

Rozanne de VeerMaren H HarmsJorn GoetChristophe CorpechotDouglas ThorburnPietro InvernizziWillem J LammersHarry LA JanssenPier Maria BattezzatiFrederik Nevens et al.

2018

A new 'treatment-response score' for AUTO immune hepatitis is predictive of LONG-TERM event-free survival and overall survival : a multicenter Belgian cohort study

Cedric SimoenJeoffrey SchoutenIsabelle ColleChristophe van SteenkisteFilip SermonAnne HoorensAnja GeertsHans Van VlierbergheXavier Verhelst

Adherence to EASL antibiotic treatment recommendations improves the outcomes of patients with cirrhosis and bacterial infections : results from the ICA 'Global Study'

S PianoV SinghP CaraceniR MaiwallC AlessandriaJ FernandezEC SoaresDJ KimSE KimM Marino et al.

Alkaline phosphatase normalization is associated with a decreased risk for liver transplantation and death in patients with primary biliary cholangitis

Carla Fiorella Murillo PerezAliya GulamhuseinChristophe CorpechotAdriaan Van der MeerHenk R Van BuurenPietro InvernizziPalak TrivediFrederik NevensMarlyn J MayoPier Maria Battezzati et al.

Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

Sander LefereF Van de VeldeSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytChristian VanhoveAnne HoorensCHRISTINE CASTELEYNXavier Verhelst et al.

Angiopoietin-2 as therapeutic target for pathological angiogenesis and inflammation in non-alcoholic steatohepatitis

Sander LefereFrederique Van de VeldeSarah RaevensSanne Van CampenhoutAster VandierendonckS NeytChristian VanhoveAnne HoorensChristophe CasteleynXavier Verhelst et al.

Angiopoietin-2 promotes pathological angiogenesis and is a novel therapeutic target in non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeAnne HoorensSarah RaevensSanne Van CampenhoutAster VandierendonckSara NeytBert VandeghinsteChristian VanhoveCharlotte Debbaut et al.

Clinical burden of hepatitis E virus infection in a tertiary care center in Flanders, Belgium

Lien CattoirFREDERIK VAN HOECKETom Van MaerkenEline NysINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstIsabelle ColleVeronik Hutse et al.

A1 Journal Article in JOURNAL OF CLINICAL VIROLOGY

Cu isotope ratio shifts in common bile duct ligated mice and correlates with the degree of cholestatic-induced liver disease

Sanne Van CampenhoutMarta Costas RodriguezAgustina Ari Murti Budi HastutiSarah RaevensAnja GeertsXavier VerhelstFrank VanhaeckeHans Van VlierbergheLindsey Devisscher

Endoglycosidase S enables a highly simplified clinical chemistry procedure for direct assessment of serum IgG undergalactosylation in chronic inflammatory disease

Dieter VanderschaegheLeander MeurisTom RaesHendrik GrootaertAnnelies Van HeckeXavier VerhelstFrederique Van de VeldeBruno LapauwHans Van VlierbergheNico Callewaert

A1 Journal Article in MOLECULAR & CELLULAR PROTEOMICS

Epidemiology, predictors and outcomes of multi drug resistant (MDR) bacterial infections in patients with cirrhosis across the world : final results of the 'Global study'

S PianoV SinghP CaraceniR MaiwallC AlessandriaJ FernandezEC SoaresDJ KimSE KimM Marino et al.

Glycome patterns of perfusate in livers before transplantation associate with primary non-function

Xavier VerhelstAnja GeertsIna JochmansDieter VanderschaegheAgnes ParadissisAude VanlanderFrederik BerrevoetGéraldine DahlqvuistFrederik NevensJacques Pirenne et al.

A1 Journal Article in GASTROENTEROLOGY

Major hepatic complications in ursodeoxycholic acid-treated patients with primary biliary cholangitis : risk factors and time trends in incidence and outcome

Maren H HarmsWillem J LammersDouglas ThorburnChristophe CorpechotPietro InvernizziHarry LA JanssenPier M BattezzatiFrederik NevensKeith D LindorAnnarosa Floreani et al.

A1 Journal Article in AMERICAN JOURNAL OF GASTROENTEROLOGY

Milder disease stage in patients with primary biliary cholangitis over a 44-year period : a changing natural history

Fiorella Murillo PerezJorn C GoetWillem J LammersAliya GulamhuseinHenk R van BuurenCyriel Y PonsioenMarco CarboneAndrew MasonChristophe CorpechotPietro Invernizzi et al.

A1 Journal Article in HEPATOLOGY

Placental growth factor inhibition targets pulmonary angiogenesis and represents a therapy for hepatopulmonary syndrome in mice

Sarah RaevensAnja GeertsAnnelies ParidaensSander LefereXavier VerhelstAnne HoorensJo Van DorpeTania MaesKen BrackeChristophe Casteleyn et al.

A1 Journal Article in HEPATOLOGY

Secondary adrenal insufficiency after treatment with budesonide for autoimmune hepatitis

Filip De MaeyerBruno LapauwAnne HoorensAnja GeertsHans Van VlierbergheXavier Verhelst

A2 Journal Article in CASE REPORTS IN GASTROENTEROLOGY

Severe hepatic and pulmonary involvement in Rendu-Osler-Weber syndrome

Xavier VerhelstAnja GeertsHans Van VlierberghePeter SmeetsCLARISSE LECLUYSE

A2 Journal Article in CASE REPORTS IN GASTROENTEROLOGY

The combination of N-acetylcysteine and anti-MT antibodies as novel therapy for acetaminophen-induced liver injury

Lindsey DevisscherDebby LaukensHannelore Van EeckhoutteSarah RaevensSander LefereAnne HoorensXavier VerhelstM LynesAnja GeertsHans Van Vlierberghe

Validation of the Amsterdam-Oxford survival prediction model in primary sclerosing cholangitis in a tertiary center setting

Jorn GoetAnnarosa FloreaniXavier VerhelstNora CazzagonLisa PeriniWillem J LammersAdriaan Van Der MeerAnnemarie C De VriesHenk R van BuurenBettina E Hansen

2017

A glycomic based serum marker analysed on postoperative day 7 after liver transplantation is an independent predictor of graft and patient survival during the first year after liver transplantation

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

A glycomic serum marker analysed at one week after liver transplantation is an independent predictor of graft loss during the first year after liver transplantation

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

A glycomic serum marker analysed at one week after liver transplantation is an independent predictor of graft loss during the first year after liver transplantation

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertHans Van Vlierberghe

A glycomics-based test predicts the development of hepatocellular carcinoma in cirrhosis

Xavier VerhelstDieter VanderschaegheLaurent CasteraTom RaesAnja GeertsClaire FrancozRoos ColmanFrançois DurandNico CallewaertHans Van Vlierberghe

A1 Journal Article in CLINICAL CANCER RESEARCH

A pretransplant glycomic signature in perfusate is predictive of primary non function after liver transplantation

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

Anti-placental growth factor therapy attenuates experimental hepatopulmonary syndrome

Sarah RaevensAnnelies ParidaensSander LefereChristophe CasteleynB JonckxXavier VerhelstHans Van VlierbergheChristophe Van SteenkisteAnja GeertsLindsey Devisscher et al.

Bilirubin is predictive of transplant-free survival even within the normal range in primary biliary cholangitis patients

Carla F Murillo PerezAliya GulamhuseinHenk R van BuurenWillem J LammersJorn C GoetCyriel Y PonsioenMarco CarboneAndrew MasonChristophe CorpechotMarlyn J Mayo et al.

Burden of hepatitis E virus infection in patients with rheumatic diseases

Peggy JacquesElizaveta PadalkoEveline VerheugenLien CattoirXavier VerhelstE NysS Van GuchtV HutseV SuinDirk Elewaut

Combination of tauroursodeoxycholic acid and N-acetylcysteine exceeds standard treatment for acetaminophen intoxication

Annelies ParidaensSarah RaevensIsabelle ColleEliene BogaertsYves-Paul VandewynckelXavier VerhelstAnne HoorensLeo A van GrunsvenHans Van VlierbergheAnja Geerts et al.

A1 Journal Article in LIVER INTERNATIONAL

Early TIPS placement as a feasible and safe strategy for variceal bleeding in high risk liver patients : a 5-year monocentre experience

Ewout VerlyXavier VerhelstHans Van VlierbergheAnja Geerts

Ernstige icterische hepatitis na eenmalig gebruik van 'ecstasy'

Ruth BottermanXavier VerhelstAnja GeertsHans Van Vlierberghe

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Hepatitis E virus serology and PCR : does the methodology matter?

Lien CattoirFREDERIK VAN HOECKETom Van MaerkenEVELINE NYSINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstIsabelle ColleVeronik Hutse et al.

A1 Journal Article in ARCHIVES OF VIROLOGY

Increase in age at diagnosis of primary biliary cholangitis over the last 40 years

CFM PerezWJ LammersJC GoetHL JanssenHR van BuurenA MasonC CorpechotP InvernizziMJ MayoPM Battezzati et al.

Koorts, keelpijn en leverfalen

Marie De GrooteJeroen GeldofAnne HoorensXavier VerhelstRoberto TroisiHarald PeetersHans Van VlierbergheAnja Geerts

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Kupffer cell pool is maintained by local proliferation and the differentiation of bone marrow monocytes into short-lived monocyte-derived Kupffer cells during non-alcoholic steatohepatitis and recovery

Lindsey DevisscherCharlotte ScottSander LefereSarah RaevensEliene BogaertsAnnelies ParidaensXavier VerhelstAnja GeertsMartin GuilliamsHans Van Vlierberghe

Modulation of the unfolded protein response by tauroursodeoxycholic acid counteracts apoptotic cell death and fibrosis in a mouse model for secondary biliary liver fibrosis

Annelies ParidaensSarah RaevensLindsey DevisscherEliene BogaertsXavier VerhelstAnne HoorensHans Van VlierbergheLeo van GrunsvenAnja GeertsIsabelle Colle

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Moving from early to moderate or advanced biochemical disease stage during follow-up is associated with an increasing risk of clinical events in primary biliary cholangitis patients

Nikolaos K GatselisJorn C GoetKalliopi ZachouWillem J LammersHarry L JanssenGideon HirschfieldChristophe CorpechotKeith D LindorPietro InvernizziMarlyn J Mayo et al.

Non-alcoholic steatohepatitis induces transient changes within the liver macrophage pool

Lindsey DevisscherCharlotte ScottSander LefereSarah RaevensEliene BogaertsAnnelies ParidaensXavier VerhelstAnja GeertsMartin GuilliamsHans Van Vlierberghe

A1 Journal Article in CELLULAR IMMUNOLOGY

Pretransplant glycomic analysis of perfusate is predictive of primary non function after liver transplantation

Xavier VerhelstAnja GeertsDieter VanderschaegheXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

Pretransplant glycomic analysis of perfusate is predictive of primary non function after liver transplantation : a proof of concept

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetNico CallewaertRoberto TroisiHans Van Vlierberghe

Recurrence of primary biliary cholangitis after liver transplantation affects graft survival : a multi-center study from the Global PBC study group

Aldo J Montano-LozaBettina E HansenDavide RoccarinaDouglas ThorburnPalak J TrivediGideon HirschfieldChristophe CorpechotRaoul PouponJerome DumortierAlexie Bosch et al.

Refractory subacute steatohepatitis after biliopancreatic diversion

Sander LefereAnne HoorensSarah RaevensRoberto TroisiXavier VerhelstHans Van VlierbergheAnja Geerts

Editorial material

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

A1 Journal Article in INTERNATIONAL JOURNAL OF OBESITY

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in obese patients with non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in obese patients with non-alcoholic fatty liver disease

Sander LefereFrederique Van de VeldeLindsey DevisscherMarlies BekaertSarah RaevensXavier VerhelstYves Van NieuwenhoveMarleen PraetAnne HoorensChristophe Van Steenkiste et al.

The GLOBE score identifies PBC patients at increased risk of liver transplantation or death in different age-categories over time

JC GoetWJ LammersA FloreaniA ParesHLA JanssenGM HirschfieldHR Van BuurenC CorpechotP InvernizziKD Lindor et al.

The potential of glycomics as prognostic biomarkers in liver disease and liver transplantation

Xavier VerhelstHans Van VlierbergheRoberto Troisi

Time trends in major hepatic complications in primary biliary cholangitis : incidence and transplant-free survival

Maren H HarmsWillem J LammersDouglas ThorburnChristophe CorpechotPietro InvernizziHarry L JanssenPier Maria BattezzatiFrederik NevensKeith D LindorAnnarosa Floreani et al.

Time-dependent factors associated with diminished transplant-free survival in patients with primary biliary cholangitis and an optimal response to ursodeoxycholic acid after one year of treatment

Willem J LammersJorn C GoetMarlyn J MayoAnn-Arosa FloreaniPietro InvernizziMaren H HarmsChristophe CorpechotKeith D LindorCyriel Y PonsioenHarry L Janssen et al.

2016

Association between ursodeoxycholic acid therapy and prolonged transplant-free survival among patients with primary biliary cholangitis a number needed to treat analysis

Maren H HarmsAnnarosa FloreaniDouglas ThorburnGeorge N DalekosHarry L JanssenChristophe CorpechotPietro InvernizziMarlyn J MayoPier Maria BattezzatiHenk R van Buuren et al.

Association of recently described adipokines with liver histology in biopsy-proven non-alcoholic fatty liver disease: a systematic review

Marlies BekaertXavier VerhelstAnja GeertsBruno LapauwPatrick Calders

A1 Journal Article in OBESITY REVIEWS

Cirrhosis : reviewing the literature and future perspectives

Xavier VerhelstAnja GeertsHans Van Vlierberghe

A2 Journal Article in EUROPEAN MEDICAL JOURNAL. HEPATOLOGY

Comments on the impact of genotyping method on the subtype distribution of HCV genotype 1

Celien Van den BorreWIM SCHUERMANSHans Van VlierbergheAnja GeertsXavier VerhelstElizaveta Padalko

A1 Journal Article in JOURNAL OF CLINICAL VIROLOGY

Effect of prolyl hydroxylase domain 2 haplodeficiency on liver progenitor cell characteristics in early mouse hepatocarcinogenesis

Eliene BogaertsAnnelies ParidaensXavier VerhelstPeter CarmelietAnja GeertsHans Van VlierbergheLindsey Devisscher

A1 Journal Article in EXCLI JOURNAL

Enuresis nocturna : a malignant symptom?

K VlaemynckBram De WildeRoberto TroisiXavier RogiersAnja GeertsXavier VerhelstHans Van VlierbergheRuth De Bruyne

Fototoxiciteit na de inname van simeprevir voor de behandeling van hepatitis C

Hendrik ThoenFlorence DesmidtAnja GeertsIsabelle HoorensHans Van VlierbergheXavier Verhelst

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Heads or tails : genotyping of hepatitis C virus concerning the 2k/1b circulating recombinant form

WIM SCHUERMANSHans OrlentIsabelle DesomberePatrick DescheemaekerHans Van VlierbergheAnja GeertsXavier VerhelstMarijke ReyndersElizaveta Padalko

A1 Journal Article in INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Health-related quality of life improves further after liver transplantation and is influenced by length of stay

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheProf dr Carine PoppeXavier Verhelst

Hepatitis E virus seroprevalence in East- and West Flanders, Belgium : comparison between 2011 and 2016

L CattoirE NysHans Van VlierbergheAnja GeertsXavier VerhelstElizaveta Padalko

Hypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease

Sander LefereChristophe Van SteenkisteXavier VerhelstHans Van VlierbergheLindsey DevisscherAnja Geerts

A1 Journal Article in CELLULAR AND MOLECULAR LIFE SCIENCES

Impact of the genotyping method on the distribution of hepatitis C virus subtypes of genotype 1

C Van den BorreW SchuermansHans Van VlierbergheAnja GeertsXavier VerhelstE Padalko

Kinetics of pulmonary angiogenesis in mouse common bile duct ligation-induced liver fibrosis

Sarah RaevensLindsey DevisscherAnnelies ParidaensEliene BogaertsSander LefereYves-Paul VandewynckelCHRISTINE CASTELEYNKen BrackeTania MaesXavier Verhelst et al.

Longitudinal transient elastography measurements used in follow-up for patients with cystic fibrosis

Stephanie Van BiervlietHUGO VERDIEVELStefanie Vande VeldeRuth De BruyneDanny De LoozeXavier VerhelstAnja GeertsEddy RobberechtHans Van Vlierberghe

A1 Journal Article in ULTRASOUND IN MEDICINE AND BIOLOGY

Massief subcapsulair leverhematoom in een zwangerschap verwikkeld met het HELLP-syndroom

Hendrik ThoenSaartje ThijsHans Van VlierbergheXavier VerhelstAnja Geerts

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma

Yves-Paul VandewynckelCéline CouckeDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsAster VandierendonckSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

A1 Journal Article in ONCOTARGET

Next-generation proteasome inhibitor oprozomib synergizes with modulators of the unfolded protein response to suppress hepatocellular carcinoma

Yves-Paul VandewynckelCéline CouckeDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsAster VandierendonckSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

Placental growth factor inhibition alleviates hepatopulmonary syndrome in mice

Sarah RaevensAnnelies ParidaensSander LefereBart JonckxXavier VerhelstHans Van VlierbergheChristophe Van SteenkisteAnja GeertsLindsey DevisscherIsabelle Colle

Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherEliene BogaertsAnnelies ParidaensAnja Van den BusscheSarah RaevensXavier VerhelstChristophe Van SteenkisteBart Jonckx et al.

A1 Journal Article in BMC CANCER

Quality of life after liver transplantation : state of the art

Louis OnghenaWouter DeveltereProf dr Carine PoppeAnja GeertsRoberto TroisiAude VanlanderFrederik BerrevoetXavier RogiersHans Van VlierbergheXavier Verhelst

A2 Journal Article in WORLD JOURNAL OF HEPATOLOGY

Reduced expression of chemerin in visceral adipose tissue associates with hepatic steatosis in patients with obesity

Marlies BekaertMargriet OuwensTina HörbeltFrederique Van de VeldePia FahlbuschDaniella Herzfeld de WizaYves Van NieuwenhovePatrick CaldersMarleen PraetAnne Hoorens et al.

A1 Journal Article in OBESITY

Serum N-glycans show distinct alterations during acetaminophen-induced acute liver failure and are predictive of transplant free survival : a proof-of-concept

Xavier VerhelstAnja GeertsXavier RogiersAude VanlanderFrederik BerrevoetFrançois DurandRoberto TroisiHans Van Vlierberghe

Successful treatment of HCV-associated B-cell non-Hodgkin lymphomas with direct-acting antiviral agents

FREDERIK DE CLERCKAnja GeertsLieve BrochezReinhart SpeeckaertTom BoterbergHans Van VlierbergheXavier Verhelst

A1 Journal Article in JOURNAL OF CLINICAL GASTROENTEROLOGY

The GLOBE score identifies PBC patients at increased risk of liver transplantation or death during follow-up

Jorn C GoetWillem J LammersHarry L JanssenGideon M HirschfieldChristophe CorpechotKeith D LindorPietro InvernizziMarlyn J MayoPier Maria BattezzatiFrederik Nevens et al.

The bile acid tauroursodeoxycholic acid cooperates with N-acetylcysteine in the treatment of experimental acetaminophen-induced hepatotoxicity

Annelies ParidaensLindsey DevisscherSarah RaevensEliene BogaertsYves-Paul VandewynckelXavier VerhelstI MannaertsL Van GrunsvenHans Van VlierbergheIsabelle Colle et al.

The role of macrophages in obesity-driven chronic liver disease

Lindsey DevisscherXavier VerhelstIsabelle ColleHans Van VlierbergheAnja Geerts

A1 Journal Article in JOURNAL OF LEUKOCYTE BIOLOGY

The unfolded protein response underlies microenvironmental stress-induced phenotype switching leading to stemness and chemoresistance in human hepatocellular carcinoma

Yves-Paul VandewynckelO GovaereAster VandierendonckDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsSarah RaevensXavier VerhelstChristophe Van Steenkiste et al.

2015

Assesment of serum glycomics (GlycoCirrhoTest) for risk prediction of hepatocellular carcinoma development in patients with cirrhosis

Xavier VerhelstDieter VanderschaegheLaurent CasteraAnja GeertsNathalie GoutteClaire FrancozFrançois DurandNico CallewaertHans Van Vlierberghe

Assesment of serum glycomics (GlycoCirrhoTest) for risk prediction of hepatocellular carcinoma development in patients with cirrhosis

Xavier VerhelstDieter VanderschaegheLaurent CasteraAnja GeertsNathalie GoutteClaire FrancozFrançois DurandNico CallewaertHans Van Vlierberghe

Evaluation of the value of serum glycomics (GlycoCirrhoTest) for risk prediction of hepatocellular carcinoma in compensated cirrhosis

Xavier VerhelstDieter VanderschaegheLaurent CasteraAnja GeertsNathalie GoutteClaire FrancozFrançois DurandNico CallewaertHans Van Vlierberghe

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Wouter DeveltereLouis OnghenaXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe

Health-related quality of life is improved after liver transplantation and is related to disease acceptance, helplessness and perceived disease benefits

Louis OnghenaWouter DeveltereXavier RogiersRoberto TroisiFrederik BerrevoetAude VanlanderAnja GeertsHans Van VlierbergheXavier VerhelstProf dr Carine Poppe

Hepatitis E virus serology and PCR : does the methodology matter?

Lien CattoirFREDERIK VAN HOECKETom Van MaerkenEVELINE NYSINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstHans Van VlierbergheElizaveta Padalko

Hepatopulmonary syndrome and portopulmonary hypertension : recent knowledge in pathogenesis and overview of clinical assessment

Sarah RaevensAnja GeertsChristophe Van SteenkisteXavier VerhelstHans Van VlierbergheIsabelle Colle

A1 Journal Article in LIVER INTERNATIONAL

IgG4-related cholangitis : case report and literature review

ANNELEEN DE BOTHHans Van VlierbergheAnja GeertsLouis LibbrechtXavier Verhelst

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Intramuscular hepatitis B immunoglobulins for reinfection control after liver transplantation: a cost-saving alternative

Eva HulstaertXavier VerhelstAnja GeertsHans Van Vlierberghe

A1 Journal Article in JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH

Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy

Yves-Paul VandewynckelDebby LaukensEliene BogaertsAnnelies ParidaensAnja Van den BusscheXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis Libbrecht et al.

A1 Journal Article in HEPATOLOGY INTERNATIONAL

Multicenter Belgian experience of sofosbuvir (medical need program) in very difficult-to-treat HCV patients: safety and efficacy results

Delphine DegréWim LalemanXavier VerhelstAnne LamproyeThomas VanwolleghemThierry GustotPeter StarkelNicolas LanthierPeter MichielsenJean Delwaide et al.

Multicenter Belgian experience of sofosbuvir medical need program in pre- and post liver transplantation patients : safety and efficacy results

Delphine DegreWim LalemanXavier VerhelstAnne LamproyeThomas VanwolleghemThierry GustotPeter StarkelNicolas LanthierPeter MichielsenJean Delwaide et al.

Phase I dose-escalation study evaluating the safety and pharmacokinetics of oral artesunate in patients with advanced hepatocullular carcinoma (DESPARTH trial)

Yves-Paul VandewynckelK RombautsXavier VerhelstLucas Van BortelBart De SpiegeleerAnja GeertsHans Van Vlierberghe

Placental growth factor inhibition modulates the interplay between hypoxia and the unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstAnja Van den BusscheSarah RaevensChristophe Van SteenkisteB Jonckx et al.

Role of angiogenic factors/cell adhesion markers in serum of cirrhotic patients with hepatopulmonary syndrome

Sarah RaevensStephanie CoulonChristophe Van SteenkisteRoos ColmanXavier VerhelstHans Van VlierbergheAnja GeertsThomas PerkmannThomas HorvatitsValentin Fuhrmann et al.

A1 Journal Article in LIVER INTERNATIONAL

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstAnja Van den BusscheSarah RaevensChristophe Van SteenkisteMarleen Van Troys et al.

A1 Journal Article in ONCOTARGET

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Yves-Paul VandewynckelDebby LaukensLindsey DevisscherAnnelies ParidaensEliene BogaertsXavier VerhelstA Van den BusscheSarah RaevensChristophe Van SteenkisteMarleen Van Troys et al.

Time-dependent effect of hypoxia on tumor progression and liver progenitor cell markers in primary liver tumors

Eliene BogaertsFemke HeindryckxLindsey DevisscherAnnelies ParidaensYves-Paul VandewynckelAnja Van den BusscheXavier VerhelstLouis LibbrechtLeo A van GrunsvenAnja Geerts et al.

A1 Journal Article in PLOS ONE

Varices, portal hypertensive gastropathy and GAVE

Isabelle ColleXavier VerhelstAnja GeertsHans Van Vlierberghe

Bookchapter in Cirrhosis : a practical guide to management

2014

Clinical burden of hepatitis E infections in Belgium

Elizaveta PadalkoFREDERIK VAN HOECKETom Van MaerkenLien CattoirEVELINE NYSINGE RYCKAERTMatthias De BoulleAnja GeertsXavier VerhelstIsabelle Colle et al.

Cutaneous infection by Alternaria infectoria in a liver transplant recipient: a case report

E CoussensS RoggeMarc HaspeslaghAnja GeertsXavier VerhelstHans Van VlierbergheRoberto TroisiIsabelle Colle

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Intramuscular hepatitis B immunoglobulines for reinfection control, a single centre experience

Eva HulstaertAnja GeertsXavier VerhelstAude VanlanderVINCENZO SCUDERIDavid LamFrederik BerrevoetXavier RogiersRoberto TroisiHans Van Vlierberghe

Optimal use of corticosteroids in gastroenterology and hepatology

Xavier VerhelstMartine De VosHans Van Vlierberghe

A2 Journal Article in JOURNAL OF TRANSLATIONAL INTERNAL MEDICINE

Temporal dynamics and therapeutic potential of the unfolded protein espouse in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis Libbrecht et al.

Temporal dynamics and therapeutic potential of the unfolded protein response in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van SteenkisteBenedicte DescampsChristian VanhoveLouis Libbrecht et al.

Therapeutic effects of artesunate in hepatocellular carcinoma : repurposing an ancient antimalarial agent

Yves-Paul VandewynckelDebby LaukensAnja GeertsChristian VanhoveBenedicte DescampsLindsey DevisscherEliene BogaertsAnnelies ParidaensXavier VerhelstChristophe Van Steenkiste et al.

Therapeutic effects of artesunate in hepatocellular carcinoma: repurposing an ancient antimalarial agent

Yves-Paul VandewynckelDebby LaukensAnja GeertsChristian VanhoveBenedicte DescampsIsabelle ColleLindsey DevisscherEliene BogaertsAnnelies ParidaensXavier Verhelst et al.

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Treatment of HCC with intra-arterial yttrium-90 microspheres for downstaging patients to transplantation

Kathia De ManLuc DefreyneElisabeth DhondtELLEN DELANGHEXavier VerhelstPeter SmeetsHans Van VlierbergheAnja GeertsRoberto TroisiXavier Rogiers et al.

2013

Anale last : vreemde duikers

Xavier VerhelstMyriam WatelleS ThomasFilip MoermanIsabelle Colle

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

Biomarkers for the diagnosis of acute cellular rejection in liver transplant recipients: a review

Xavier VerhelstRoberto TroisiIsabelle ColleAnja GeertsHans Van Vlierberghe

A1 Journal Article in HEPATOLOGY RESEARCH

Double balloon enteroscopy is an adequate therapeutic tool to address angiodysplasia-related anemia

Michael JanssensXavier VerhelstPieter HindryckxDanny De LoozeMartine De VosHarald Peeters

Hepatocellular carcinoma (HCC) treatment with intra-arterial radiolabelled lipiodol versus Yttrium-90-microspheres: a retrospective survival analysis.

Kathia De ManLuc DefreyneELLEN DELANGHEElisabeth DhondtHans Van VlierbergheAnja GeertsXavier VerhelstRoberto TroisiBieke Lambert

Oral vasodilator therapy in patients with moderate to severe portopulmonary hypertension as a bridge to liver transplantation

Sarah RaevensMichel De PauwKOEN REYNTJENSAnja GeertsXavier VerhelstFrederik BerrevoetXavier RogiersRoberto TroisiHans Van VlierbergheIsabelle Colle

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Pathophysiology and management of post resection liver failure

Isabelle ColleXavier VerhelstAude VanlanderAnja GeertsHans Van VlierbergheFrederik BerrevoetXavier RogiersRoberto Troisi

A1 Journal Article in ACTA CHIRURGICA BELGICA

The paradox of the unfolded protein response in cancer

Yves-Paul VandewynckelDebby LaukensAnja GeertsEliene BogaertsAnnelies ParidaensXavier VerhelstSophie JanssensFemke HeindryckxHans Van Vlierberghe

A1 Journal Article in ANTICANCER RESEARCH

The therapeutic potential of artesunate in hepatocellular carcinoma

Yves-Paul VandewynckelDebby LaukensAnja GeertsIsabelle ColleLouis LibbrechtEliene BogaertsLindsey DevisscherAnnelies ParidaensXavier VerhelstChristian Vanhove et al.

Treatment of hepatocellular carcinoma (HCC) with intraarterial yttrium-90 microspheres for downstaging patients to transplantation

Kathia De ManLuc DefreyneELLEN DELANGHEPeter SmeetsXavier VerhelstAnja GeertsHans Van VlierbergheXavier RogiersRoberto TroisiBieke Lambert

2012

A case of emphysematous gastritis

Xavier VerhelstM. CabooterV. de WildeP. LaukensH. Orlent

A1 Journal Article in Endoscopy

Storage of blood samples at 4°C during one week does not affect protein glycosylation in healthy human volunteers

Xavier VerhelstBRAM BLOMMEWim DelvaNico CallewaertHans Van Vlierberghe

2011

Progressive multifocal leukoencephalopathy in liver transplant recipients : a case report and review of the literature

Xavier VerhelstGeert VanhoorenLudo VanopdenboschJan CasselmanWim LalemanJacques PirenneFrederik NevensHans Orlent

A1 Journal Article in TRANSPLANT INTERNATIONAL

2010

Subfulminant hepatitis B during treatment with adalimumab in a patient with rheumatoid arthritis and chronic hepatitis B

Xavier VerhelstHans OrlentIsabelle ColleAnja GeertsMartine De VosHans Van Vlierberghe

A1 Journal Article in EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

2009

Acute hepatitis after treatment for hair loss with oral green tea extracts (Camellia sinensis)

Xavier VerhelstP BurvenichDiederik Van SassenbroeckC GabrielM LootensD Baert

A1 Journal Article in ACTA GASTRO-ENTEROLOGICA BELGICA

Een zeldzame oorzaak van pneumothorax en pneumomediastinum

Xavier VerhelstAndre CarlierXimena Elzo KraemerPaul Taelman

A2 Journal Article in TIJDSCHRIFT VOOR GENEESKUNDE

2006

Leflunomide and methotrexate combination therapy in daily clinical practice

A DendoovenLEEN DE RYCKEXavier VerhelstHerman MielantsEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES

2005

Rheumatoid factor, but not anti-cyclic citrullinated peptide antibodies, is modulated by infliximab treatment in rheumatoid arthritis

Leen De RyckeXavier VerhelstElli KruithofFilip Van den BoschIlse HoffmanEric VeysFilip De Keyser

A1 Journal Article in ANNALS OF THE RHEUMATIC DISEASES