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Researcher
Wim Van Criekinge
Profile
Projects
Publications
Activities
Awards & Distinctions
284
Results
2025
The molecular causes and clinical consequences of dysregulation at the HM13 locus in cancer
Floris Voorthuijzen
Tim De Meyer
Wim Van Criekinge
Dissertation
2025
2024
A genomic urine assay for surveillance of patients with bladder cancer treated with radiotherapy
Florus C. de Jong
Iris G. Iflé
Angelique C. van der Made
Denise Kooper
Joep J. de Jong
Martine Franckena
Tahlita C.M. Zuiverloon
Wim Van Criekinge
Luca Incrocci
Ellen C. Zwarthoff
et al.
A1
Journal Article
in
EUROPEAN UROLOGY OPEN SCIENCE
2024
Beyond correlations : a causal perspective on host-microbiome interactions
Steff Taelman
Wim Van Criekinge
Michiel Stock
Liesbeth Ceelen
Dissertation
2024
Development of a novel assay to characterize the HIV-1 reservoir using long-read sequencing
Laurens Lambrechts
Linos Vandekerckhove
Wim Van Criekinge
Dissertation
2024
Hyperdimensional computing : a fast, robust, and interpretable paradigm for biological data
Michiel Stock
Wim Van Criekinge
Dimitri Boeckaerts
Steff Taelman
Maxime Van Haeverbeke
Pieter Dewulf
Bernard De Baets
A1
Journal Article
in
PLOS COMPUTATIONAL BIOLOGY
2024
Loss-of-imprinting of HM13 leads to poor prognosis in clear cell renal cell carcinoma
Floris Voorthuijzen
Cedric Stroobandt
Wim Van Criekinge
Tine Goovaerts
Tim De Meyer
A1
Journal Article
in
BIOMOLECULES
2024
Multimodal deregulation of imprinted gene HM13 : a pan-cancer study
Floris Voorthuijzen
Cedric Stroobandt
Jeroen Galle
Louis Coussement
Jim Clauwaert
Tine Goovaerts
Ryan Englander
Olga Anczukow
Gerben Menschaert
Wim Van Criekinge
et al.
C3
Conference
2024
Quantitative transcriptomic and epigenomic data analysis : a primer
Louis Coussement
Wim Van Criekinge
Tim De Meyer
A2
Journal Article
in
BIOINFORMATICS ADVANCES
2024
The role of Helicobacter suis, Fusobacterium gastrosuis, and the pars oesophageal microbiota in gastric ulceration in slaughter pigs receiving meal or pelleted feed
Emily Taillieu
Steff Taelman
Sofie De Bruyckere
Evy Goossens
Ilias Chantziaras
Christophe Van Steenkiste
Peter Yde
Steven Hanssens
Dimitri De Meyer
Wim Van Criekinge
et al.
A1
Journal Article
in
VETERINARY RESEARCH
2024
2023
A bioinformatics-driven exploration of the evolutionary (dis)advantages of epigenetics
Louis Coussement
Tim De Meyer
Wim Van Criekinge
Dissertation
2023
A urine-based genomic assay improves risk stratification for patients with high-risk hematuria stratified according to the American Urological Association guidelines
Joep J. de Jong
Olga M. Pijpers
Kim. E.M. van Kessel
Joost. L. Boormans
Wim Van Criekinge
Ellen C. Zwarthoff
Yair Lotan
A1
Journal Article
in
EUROPEAN UROLOGY ONCOLOGY
2023
Challenges in neoantigen-directed therapeutics
Lien Lybaert
Steve Lefever
Bruno Fant
Evelien Smits
Bruno De Geest
Karine Breckpot
Luc Dirix
Steven A. Feldman
Wim Van Criekinge
Kris Thielemans
et al.
A1
Journal Article
in
CANCER CELL
2023
Cost-effectiveness of an urinary biomarker panel in combination with MRI for prostate cancer diagnosis
Tim M. Govers
Matthew J Resnick
Ardeshir R. Rastinehad
Laura Caba
Jack Groskopf
Wim Van Criekinge
A1
Journal Article
in
WORLD JOURNAL OF UROLOGY
2023
HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization
Laurens Lambrechts
Noah Bonine
Rita Verstraeten
Marion Pardons
Ytse Noppe
Sofie Rutsaert
Filip Van Nieuwerburgh
Wim Van Criekinge
Basiel Cole
Linos Vandekerckhove
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2023
HIV-PULSE : a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization
Laurens Lambrechts
Noah Bonine
Rita Verstraeten
Marion Pardons
Ytse Noppe
Sofie Rutsaert
Filip Van Nieuwerburgh
Wim Van Criekinge
Basiel Cole
Linos Vandekerckhove
Preprint
2023
Multimodal deregulation of imprinted gene HM13 leads to pan-cancer upregulation of putative oncogene MCTS2
Floris Voorthuijzen
Tine Goovaerts
Cedric Stroobandt
Jeroen Galle
Ryan Englander
Olga Anczukow
Wim Van Criekinge
Gerben Menschaert
Tim De Meyer
C3
Conference
2023
Variational autoencoders to predict DNA-methylation age and provide biological insights in age-related health and disease
Sandra Steyaert
Adriaan Verhelle
Wim Van Criekinge
Preprint
2023
2022
A genomic urine assay to detect urinary tract recurrences in patients with bladder cancer treated with radiotherapy
Florus C. de Jong
Iris I. Ifle
Denise Kooper
Angelique C. J. van der Made
Joep J. De Jong
Tahlita C. M. Zuiverloon
Luca Incrocci
Wim Van Criekinge
Martine Franckena
Joost L. Boormans
et al.
C3
Conference
2022
A urine-based molecular assay refines the risk stratification of the recent American Urological Association guideline on hematuria
Joep de Jong
Olga Pijpers
Kim van Kessel
Joost Boormans
Wim Van Criekinge
Ellen Zwarthoff
Yair Lotan
C3
Conference
2022
Copy number gain and loss-of-imprinting lead to HM13 intron retention across multiple cancer types
Floris Voorthuijzen
Tine Goovaerts
Cedric Stroobandt
Jeroen Galle
Wim Van Criekinge
Tim De Meyer
C3
Conference
2022
Exploring PhaLP, an open source portal for Phage Lytic Proteins, to engineer modular enzybiotics against vancomycin-resistant Enterococcus faecalis
Bjorn Criel
Wim Van Criekinge
Yves Briers
C3
Conference
2022
Exploring PhaLP, an open source portal for Phage Lytic Proteins, to engineer modular enzybiotics against vancomycin-resistant Enterococcus faecalis
Bjorn Criel
Wim Van Criekinge
Yves Briers
C3
Conference
2022
Haplotyping pharmacogenes using TLA combined with Illumina or Nanopore sequencing
Laurentijn Tilleman
Kaat Rubben
Wim Van Criekinge
Dieter Deforce
Filip Van Nieuwerburgh
A1
Journal Article
in
SCIENTIFIC REPORTS
2022
Identification and characterization of eukaryotic small open reading frames and microproteins
Marlies Peeters
Gerben Menschaert
Liesbet Temmerman
Wim Van Criekinge
Dissertation
2022
Machine learning-guided engineering of modular enzybiotics to target vancomycin-resistant Enterococcus faecalis infections of the urinary tract
Bjorn Criel
Wim Van Criekinge
Yves Briers
C3
Conference
2022
Technical considerations in PCR-based assay design for diagnostic DNA methylation cancer biomarkers
Maartje Massen
Kim Lommen
Kim A. D. Wouters
Johan Vandersmissen
Wim Van Criekinge
James G. Herman
Veerle Melotte
Leo J. Schouten
Manon van Engeland
Kim M. Smits
A1
Journal Article
in
CLINICAL EPIGENETICS
2022
Unraveling the molecular framework of de novo shoot organogenesis in Arabidopsis thaliana
Robin Lardon
Danny Geelen
Wim Van Criekinge
Dissertation
2022
2021
Clinical use of the SelectMDx urinary-biomarker test with or without mpMRI in prostate cancer diagnosis : a prospective, multicenter study in biopsy-naive men
Rianne J. Hendriks
Marloes M. G. van der Leest
Bas Israel
Gerjon Hannink
Anglita YantiSetiasti
Erik B. Cornel
Christina A. Hulsbergen-van de Kaa
O. Sjoerd Klaver
J. P. Michiel Sedelaar
Wim Van Criekinge
et al.
A1
Journal Article
in
PROSTATE CANCER AND PROSTATIC DISEASES
2021
DNA methylation regulates transcription factor-specific neurodevelopmental but not sexually dimorphic gene expression dynamics in zebra finch telencephalon
Jolien Diddens
Louis Coussement
Carolina Frankl-Vilches
Gaurav Majumdar
Sandra Steyaert
Sita M. Ter Haar
Jeroen Galle
Ellen De Meester
Sarah De Keulenaer
Wim Van Criekinge
et al.
A1
Journal Article
in
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
2021
Evaluation of the new American Urological Association guidelines risk classification for hematuria
Solomon L. Woldu
Casey K. Ng
Ronald K. Loo
Jeff M. Slezak
Steven J. Jacobsen
Wei Shen Tan
John D. Kelly
Tony Lough
David Darling
Kim E. M. van Kessel
et al.
A1
Journal Article
in
JOURNAL OF UROLOGY
2021
PhaLP : a database for the study of phage lytic proteins and their evolution
Bjorn Criel
Steff Taelman
Wim Van Criekinge
Michiel Stock
Yves Briers
A1
Journal Article
in
VIRUSES-BASEL
2021
Single cell epigenetic visualization assay
Sam Kint
Wim Van Criekinge
Linos Vandekerckhove
Winnok H De Vos
Karol Bomsztyk
Diane S Krause
Oleg Denisenko
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2021
Spectral prediction features as a solution for the search space size problem in proteogenomics
Steven Verbruggen
Siegfried Gessulat
Ralf Gabriels
Anna Matsaroki
Hendrik Van de Voorde
Bernhard Kuster
Sven Degroeve
Lennart Martens
Wim Van Criekinge
Mathias Wilhelm
et al.
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2021
2020
A urine assay to triage patients with hematuria for cystoscopy
Kim E. M. van Kessel
Joep J. de Jong
Angelique C. J. Ziel-van der Made
Hossain Roshani
Stefan M. Haensel
Josien H. Wolterbeek
Egbert R. Boeve
Eric H. G. M. Oomens
Niels J. van Casteren
Manuel Krispin
et al.
C3
Conference
2020
A urine based genomic assay to triage patients with hematuria for cystoscopy
Kim E. M. van Kessel
Joep J. de Jong
Angelique C. J. Ziel-van der Made
Hossain Roshani
Stefan M. Haensel
Josien H. Wolterbeek
Egbert R. Boeve
Eric H. G. M. Oomens
Niels J. van Casteren
Manuel Krispin
et al.
A1
Journal Article
in
JOURNAL OF UROLOGY
2020
Exploring allele-specific expression mechanisms in health and disease
Tine Goovaerts
Tim De Meyer
Wim Van Criekinge
Dissertation
2020
Exploring methods to measure DNA methylation in the context of HIV-1
Sam Kint
Wim Van Criekinge
Linos Vandekerckhove
Wim Trypsteen
Dissertation
2020
The SelectMDx urinary-biomarker test : role in the detection of high-grade prostate cancer and in combination with multi-parametric magnetic resonance imaging in a contemporary prospective cohort of biopsy-naive men
Rianne Hendriks
Marloes van der Leest
Bas Israel
Gerjon Hannink
Anglita Yanti Setiasti
Erik Cornel
Christina Hulsbergen-van de Kaa
Sjoerd Klaver
Michiel Sedelaar
Wim Van Criekinge
et al.
C3
Conference
2020
The elusive source of HIV-1 rebound after treatment interruption
Laurens Lambrechts
Basiel Cole
Marie-Angélique De Scheerder
Zoe Boyer
Ytse Noppe
Katie Fisher
John-Sebastian Eden
Wim Van Criekinge
Lisa Frenkel
Sarah Palmer
et al.
C3
Conference
2020
The potential influence of human Y-chromosome haplogroup on COVID-19 prevalence and mortality
Joris Delanghe
Marc De Buyzere
Sander De Bruyne
Wim Van Criekinge
Marijn Speeckaert
A1
Journal Article
in
ANNALS OF ONCOLOGY
2020
The proteogenomic hunt for new proteoforms using ribosome profiling
Steven Verbruggen
Wim Van Criekinge
Gerben Menschaert
Petra Van Damme
Dissertation
2020
Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals
Sam Kint
Wim Trypsteen
Ward De Spiegelaere
Eva Malatinková
Sabine Kinloch-de Loes
Tim De Meyer
Wim Van Criekinge
Linos Vandekerckhove
A1
Journal Article
in
CLINICAL EPIGENETICS
2020
Validation of a 2-gene mRNA urine test for the detection of >= GG2 prostate cancer in an opportunistic screening population
Jose Rubio-Briones
Angel Borque-Fernando
Luis M. Esteban
Juan M. Mascaros
Miguel Ramirez-Backhaus
Juan Casanova
Argimiro Collado
Carmen Mir
Alvaro Gomez-Ferrer
Augusto Wong
et al.
A1
Journal Article
in
PROSTATE
2020
2019
A proteogenomic endeavour investigating the unexplored domain of putatively coding small open reading frames
Volodimir Olexiouk
Wim Van Criekinge
Gerben Menschaert
Dissertation
2019
Clinical utility of ConfirmMDx for prostate cancer in a community urology practice
Paul Yonover
Sandra Steyaert
Justin Cohen
Celeste Ruiz
Karolina Grafczynska
Elizabeth Garcia
Jessica DeHart
Michael Brawer
Jack Groskopf
Wim Van Criekinge
C3
Conference
2019
Clinical utility study of confirms mdx for prostate cancer in a community urology practice
Paul Yonover
Sandra Steyaert
Justin J. Cohen
Celeste Ruiz
Karolina Grafczynska
Elizabeth Garcia
Jessica DeHart
Michael Brawer
Jack Groskopf
Wim Van Criekinge
C3
Conference
2019
Clinically significant prostate cancer diagnosed using a urinary molecular biomarker-based risk score : two case reports
Pieter Minnee
Daphne Hessels
Jack A Schalken
Wim Van Criekinge
A1
Journal Article
in
BMC UROLOGY
2019
Cost-effectiveness of SelectMDx for prostate cancer in four European countries : a comparative modeling study
Tim M. Govers
Daphne Hessels
Virginie Vlaeminck-Guillem
Bernd J. Schmitz-Draeger
Christian G. Stief
Claudio Martinez-Ballesteros
Matteo Ferro
Angel Borque-Fernando
Jose Rubio-Briones
J. P. Michiel Sedelaarll
et al.
A1
Journal Article
in
PROSTATE CANCER AND PROSTATIC DISEASES
2019
Cost-effectiveness of a two-gene urine biomarker assay in MRI strategies for the initial detection of prostate cancer
Tim Govers
Matthew J. Resnick
Geert Trooskens
Wim Van Criekinge
Jack A. Schalken
C3
Conference
2019
Evaluation of an epigenetic assay for predicting repeat prostate biopsy outcome in African American men
Robert L, Jr Waterhouse
Leander Van Neste
Kelvin A Moses
Carlton Barnswell
Jonathan L Silberstein
Mark Jalkut
Ronald Tutrone
James Sylora
Ronald Anglade
Myron Murdock
et al.
A1
Journal Article
in
UROLOGY
2019
MEXPRESS update 2019
Alexander Koch
Jana Jeschke
Wim Van Criekinge
Manon van Engeland
Tim De Meyer
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2019
MGMT promoter methylation cutoff with safety margin for selecting glioblastoma patients into trials omitting temozolomide : a pooled analysis of four clinical trials
Monika E Hegi
Els Genbrugge
Thierry Gorlia
Roger Stupp
Mark R Gilbert
Olivier L Chinot
L Burt Nabors
Greg Jones
Wim Van Criekinge
Josef Straub
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2019
Multicenter optimization and validation of a 2-gene mRNA urine test for detection of clinically significant prostate cancer before initial prostate biopsy
Alexander Haese
Geert Trooskens
Sandra Steyaert
Daphne Hessels
Michael Brawer
Virginie Vlaeminck-Guillem
Alain Ruffion
Derya Tilki
Jack Schalken
Jack Groskopf
et al.
A1
Journal Article
in
JOURNAL OF UROLOGY
2019
PROTEOFORMER 2.0 : further developments in the ribosome profiling-assisted proteogenomic hunt for new proteoforms
Steven Verbruggen
Elvis Ndah
Wim Van Criekinge
Siegfried Gessulat
Bernhard Kuster
Mathias Wilhelm
Gerben Menschaert
Petra Van Damme
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2019
Urinary molecular biomarker test impacts prostate biopsy decision making in clinical practice
Neal Shore
Jason Hafron
Timothy Langford
Marshall Stein
Jessica DeHart
Michael Brawer
Daphne Hessels
Jack Schalken
Wim Van Criekinge
Jack Groskopf
et al.
A2
Journal Article
in
UROLOGY PRACTICE
2019
Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men
Derya Tilki
Daphne Hessels
Geert Trooskens
Susan Mulders
Michael Brawer
Wim Van Criekinge
Jack Groskopf
Alexander Haese
C3
Conference
2019
2018
A comprehensive overview of genomic imprinting in breast and its deregulation in cancer
Tine Goovaerts
Sandra Steyaert
Chari Vandenbussche
Jeroen Galle
Olivier Thas
Wim Van Criekinge
Tim De Meyer
A1
Journal Article
in
NATURE COMMUNICATIONS
2018
An update on sORFs.org : a repository of small ORFs identified by ribosome profiling
Volodimir Olexiouk
Wim Van Criekinge
Gerben Menschaert
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2018
Analysis of DNA methylation in cancer : location revisited
Alexander Koch
Sophie C Joosten
Zheng Feng
Tim C de Ruijter
Muriel X Draht
Veerle Melotte
Kim M Smits
Jurgen Veeck
James G Herman
Leander Van Neste
et al.
A1
Journal Article
in
NATURE REVIEWS CLINICAL ONCOLOGY
2018
Cost-effectiveness of SelectMDX for prostate cancer in four European countries : a modelling study
Daphne Hessels
Tim Govers
Wim Van Criekinge
Virginie Vlaeminck-Guillem
Bernd Schmitz-drager
Christian Stief
Jack Schalken
C3
Conference
2018
Epigenetic markers in circulating cell-free DNA as prognostic markers for survival of castration-resistant prostate cancer patients
Rianne J Hendriks
Siebren Dijkstra
Frank P Smit
Johan Vandersmissen
Hendrik Van de Voorde
Peter FA Mulders
Inge M van Oort
Wim Van Criekinge
Jack A Schalken
A1
Journal Article
in
PROSTATE
2018
Evaluation of bisulfite kits for DNA methylation profiling in terms of DNA fragmentation and DNA recovery using digital PCR
Sam Kint
Ward De Spiegelaere
Jonas De Kesel
Linos Vandekerckhove
Wim Van Criekinge
A1
Journal Article
in
PLOS ONE
2018
Evaluation of two urinary RNA biomarker tests with an epigenetic DNA assay for the identification of men with high-grade prostate cancer
Geert Trooskens
Anglita Yantisetiasti
Rianne Hendriks
Inge Van Oort
Peter Mulders
Christina Hulsbergen-van de Kaa
Wim Van Criekinge
Jack Schalken
C3
Conference
2018
Exploratory analysis of the human breast DNA methylation profile upon soymilk exposure
Louis Coussement
Selin Bolca
Wim Van Criekinge
Geert Trooskens
Klaas Mensaert
Katrien Poels
Nathalie Roche
Phillip Blondeel
Lode Godderis
Herman Depypere
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2018
Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1
Leonel Maldonado
Mariana Brait
Evgeny Izumchenko
Shahnaz Begum
Aditi Chatterjee
Tanusree Sen
Myriam Loyo
Alvaro Barbosa
Maria Luana Poeta
Eugene Makarev
et al.
A1
Journal Article
in
CANCER LETTERS
2018
Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA
Ruben Van Paemel
Anneleen Decock
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Franki Speleman
Wim Van Criekinge
Nadine Van Roy
Jo Vandesompele
Katleen De Preter
et al.
C3
Conference
2018
Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA
Ruben Van Paemel
Anneleen Decock
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Franki Speleman
Wim Van Criekinge
Nadine Van Roy
Jo Vandesompele
Katleen De Preter
et al.
C3
Conference
2018
Non-invasive differential diagnosis of neuroblastoma with other paediatric solid tumors using methylation profiling of circulating cell-free DNA
Ruben Van Paemel
Anneleen Decock
Charlotte Vandeputte
Tim Lammens
Genevieve Laureys
Franki Speleman
Wim Van Criekinge
Nadine Van Roy
Jo Vandesompele
Katleen De Preter
et al.
C3
Conference
2018
Prospective validation of a diagnostic urine test for bladder cancer : the Hematuria study
Kim van Kessel
Joep de Jong
Angelique Ziel-van der Made
Hossain Roshani
Stefan Haensel
Josien van Montfrans-Wolterbeek
Egbert Boeve
Eric Oomens
Niels van Casteren
Joost Boormans
et al.
C3
Conference
2018
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from type2 diabetes patients : rescue by α-ketoglutarate and TET-TDG functional reactivation
Francesco Spallotta
Chiara Cencioni
Sandra Atlante
Davide Garella
Mattia Cocco
Mattia Mori
Raffaella Mastrocola
Carsten Kuenne
Stefan Guenther
Simona Nanni
et al.
A1
Journal Article
in
CIRCULATION RESEARCH
2018
The potential of methylome sequencing in the diagnostic work : up of pediatric solid tumors
Ruben Van Paemel
Charlotte Vandeputte
Bram De Wilde
Katleen De Preter
Nadine Van Roy
Jo Vandesompele
Tim Lammens
Wim Van Criekinge
P. Ultz
Nico Callewaert
et al.
C3
Conference
2018
2017
A four-gene promoter methylation marker panel consisting of GREM1, NEURL, LAD1, and NEFH predicts survival of clear cell renal cell cancer patients
Iris JH van Vlodrop
Sophie C Joosten
Tim De Meyer
Kim M Smits
Leander Van Neste
Veerle Melotte
Marcella MLL Baldewijns
Leo J Schouten
Piet A van den Brandt
Jana Jeschke
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2017
A urinary biomarker-based risk score correlates with multiparametric MRI for prostate cancer detection
Rianne J Hendriks
Marloes MG van der Leest
Siebren Dijkstra
Jelle O Barentsz
Wim Van Criekinge
Christina A Hulsbergen-van de Kaa
Jack A Schalken
Peter FA Mulders
Inge M van Oort
A1
Journal Article
in
PROSTATE
2017
Clinical performance of an epigenetic assay to identify occult high-grade prostate cancer in African American men
Leander Van Neste
Carlton Barnswell
Mark Jalkut
Ronald Tutrone
James Sylora
Ronald Anglade
Myron Murdock
Kelvin A Moses
Zvi Shiffman
Todd Vandenberg
et al.
C3
Conference
2017
Cost-effectiveness of a new urinary biomarker-based risk score compared to standard of care in prostate cancer diagnostics : a decision analytical model
Siebren Dijkstra
Tim M Govers
Rianne J Hendriks
Jack A Schalken
Wim Van Criekinge
Leander Van Neste
Janneke PC Grutters
John P Michiel Sedelaar
Inge M van Oort
A1
Journal Article
in
BJU INTERNATIONAL
2017
Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer
Linda JW Bosch
Geert Trooskens
Petur Snaebjornsson
Veerle MH Coupé
Sandra Mongera
Josien C Haan
Susan D Richman
Miriam Koopman
Jolien Tol
Tim De Meyer
et al.
A1
Journal Article
in
ONCOTARGET
2017
Differential analysis of genome-wide methylation and gene expression in mesenchymal stem cells of patients with fractures and osteoarthritis
Alvaro del Real
Flor M Pérez-Campo
Agustín F Fernández
Carolina Sañudo
Carmen G Ibarbia
María I Pérez-Núñez
Wim Van Criekinge
Maarten Braspenning
María A Alonso
Mario F Fraga
et al.
A1
Journal Article
in
EPIGENETICS
2017
Epigenetic profiling in cancer
Geert Trooskens
Wim Van Criekinge
Tim De Meyer
Dissertation
2017
Epigenetic risk score improves prostate cancer risk assessment
Leander Van Neste
Jack Groskopf
William E Grizzle
George W Adams
Mark S DeGuenther
Peter N Kolettis
James E Bryant
Gary P Kearney
Michael C Kearney
Wim Van Criekinge
et al.
A1
Journal Article
in
PROSTATE
2017
Epigenetic sampling effects : nephrectomy modifies the clear cell renal cell cancer methylome
Christophe Van Neste
Alexander Laird
Fiach O’Mahony
Wim Van Criekinge
Dieter Deforce
Filip Van Nieuwerburgh
Thomas Powles
David J Harrison
Grant D Stewart
Tim De Meyer
A1
Journal Article
in
CELLULAR ONCOLOGY
2017
Genome-wide DNA methylation profiling reveals methylation markers associated with 3q gain for detection of cervical precancer and cancer
Wina Verlaat
Peter JF Snijders
Putri W Novianti
Saskia M Wilting
Lise MA De Strooper
Geert Trooskens
Johan Vandersmissen
Wim Van Criekinge
G Bea A Wisman
Chris JLM Meijer
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2017
Immune cell profiling of melanoma metastases from patients treated with TriMixDC-MEL dendritic cell therapy in combination with ipilimumab
Kelly Schats
Emily A Van Vre
Isolde Debyser
Arno Vandenbroeck
Yanina Jansen
Teofila Seremet
Koen Marien
Erik Fransen
Dorien Schrijvers
Wim Van Criekinge
et al.
C3
Conference
2017
Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer
Tushar Tomar
Nicolette G Alkema
Leroy Schreuder
Gert Jan Meersma
Tim De Meyer
Wim Van Criekinge
Harry G Klip
Heidi Fiegl
Els van Nieuwenhuysen
Ignace Vergote
et al.
A1
Journal Article
in
BMC MEDICINE
2017
Novel stool-based protein biomarkers for improved colorectal cancer screening : a case-control study
Linda JW Bosch
Meike de Wit
Thang V Pham
Veerle MH Coupe
Annemieke C Hiemstra
Sander R Piersma
Gideon Oudgenoeg
George L Scheffer
Sandra Mongera
Jochim Terhaar Sive Droste
et al.
A1
Journal Article
in
ANNALS OF INTERNAL MEDICINE
2017
Prospective validation of a diagnostic urine test for bladder cancer : the HEMAturia study
Kim EM van Kessel
Joep J de Jong
Angelique CJ Ziel-van der Made
Hossain Roshani
Stefan M Haensel
Josien H van Montfrans-Wolterbeek
Egbert R Boeve
Eric HGM Oomens
Niels J van Casteren
Joost L Boormans
et al.
C3
Conference
2017
The microbiome in posttraumatic stress disorder and trauma-exposed controls : an exploratory study
Sian MJ Hemmings
Stefanie Malan-Müller
Leigh L van den Heuvel
Brittany A Demmitt
Maggie A Stanislawski
David G Smith
Adam D Bohr
Christopher E Stamper
Embriette R Hyde
James T Morton
et al.
A1
Journal Article
in
PSYCHOSOMATIC MEDICINE
2017
Validation of a DNA methylation-mutation urine assay to select patients with hematuria for cystoscopy
Kim EM van Kessel
Willemien Beukers
Irene Lurkin
Angelique Ziel-van der Made
Kirstin A van der Keur
Joost L Boormans
Lars Dyrskjøt
Mirari Márquez
Torben F Ørntoft
Francisco X Real
et al.
A1
Journal Article
in
JOURNAL OF UROLOGY
2017
2016
A genome-wide search for epigenetically regulated genes in zebra finch using MethylCap-seq and RNA-seq
Sandra Steyaert
Jolien Diddens
Jeroen Galle
Ellen De Meester
Sarah De Keulenaer
Antje Bakker
Nina Sohnius-Wilhelmi
Carolina Frankl-Vilches
Annemie Van der Linden
Wim Van Criekinge
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2016
Ability of an epigenetic assay to identify anterior prostate tumors based on a negative 12-core biopsy
Todd Matthew Morgan
Simpa Samuel Salami
John Thomas Wei
Ganesh S Palapattu
Amy Gursky
Wim Van Criekinge
Leander Van Neste
Rohit Mehra
C3
Conference
2016
BMP-SMAD signaling regulates lineage priming, but is dispensable for self-renewal in mouse embryonic stem cells
Maria Gomes Fernandes
Ruben Dries
Matthias S Roost
Stefan Semrau
Ana de Melo Bernardo
Richard P Davis
Ramprasad Ramakrishnan
Karoly Szuhai
Elke Maas
Lieve Umans
et al.
A1
Journal Article
in
STEM CELL REPORTS
2016
Clinical utility of an epigenetic assay to reduce unnecessary repeat prostate biopsies
Jason Hafron
Thanh Huynh
Ayad S Khourdaji
Richard D Sante
Wim Van Criekinge
Leander Van Neste
C3
Conference
2016
Combined DNA-methylation intensity and clinical risk score to stratify patients for high-grade disease
Leander Van Neste
Grant Stewart
Sandra Marlene Gaston
William E Grizzle
George W Adams
Gary P Kearney
Jonathan I Epstein
David James Harrison
Alan W Partin
Wim Van Criekinge
C3
Conference
2016
DNA methylation profiling of primary neuroblastoma tumors using methyl-CpG-binding domain sequencing
Anneleen Decock
Maté Ongenaert
Wim Van Criekinge
Franki Speleman
Jo Vandesompele
A1
Journal Article
in
SCIENTIFIC DATA
2016
Detection of high-grade prostate cancer using a urinary molecular biomarker-based risk score
Leander Van Neste
Rianne J Hendriks
Siebren Dijkstra
Geert Trooskens
Erik B Cornel
Sander A Jannink
Hans de Jong
Daphne Hessels
Frank P Smit
Willem JG Melchers
et al.
A1
Journal Article
in
EUROPEAN UROLOGY
2016
Developing bioinformatics applications for the analysis of epigenetic next-generation sequencing data
Sandra Steyaert
Tim De Meyer
Wim Van Criekinge
Wim Vanden Berghe
Dissertation
2016
Discovery of new methylation markers to improve screening for cervical intraepithelial neoplasia grade 2/3
A Boers
R Wang
RW van Leeuwen
HG Klip
GH de Bock
H Hollema
Wim Van Criekinge
Tim De Meyer
Simon Denil
AGJ van der Zee
et al.
A1
Journal Article
in
CLINICAL EPIGENETICS
2016
Dynamic epigenetic changes to VHL occur with sunitinib in metastatic clear cell renal cancer
Grant D Stewart
Thomas Powles
Christophe Van Neste
Alison Meynert
Fiach O'Mahony
Alexander Laird
Dieter Deforce
Filip Van Nieuwerburgh
Geert Trooskens
Wim Van Criekinge
et al.
A1
Journal Article
in
ONCOTARGET
2016
Evaluation of an epigenetic profile for the detection of bladder cancer in patients with hematuria
Kim EM van Kessel
Leander Van Neste
Irene Lurkin
Ellen C Zwarthoff
Wim Van Criekinge
A1
Journal Article
in
JOURNAL OF UROLOGY
2016
Forensic Loci Allele Database (FLAD) : automatically generated, permanent identifiers for sequenced forensic alleles
Christophe Van Neste
Wim Van Criekinge
Dieter Deforce
Filip Van Nieuwerburgh
A1
Journal Article
in
FORENSIC SCIENCE INTERNATIONAL-GENETICS
2016
Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma
Rong Wang
Robert W van Leeuwen
Aniek Boers
Harry G Klip
Tim De Meyer
Renske DM Steenbergen
Wim Van Criekinge
Ate GJ van der Zee
Ed Schuuring
G Bea A Wisman
A1
Journal Article
in
ONCOTARGET
2016
Identification and validation of WISP1 as an epigenetic regulator of metastasis in oral squamous cell carcinoma
Martijn JAM Clausen
Lieuwe J Melchers
Mirjam F Mastik
Lorian Slagter-Menkema
Harry JM Groen
Bernard FAM van der Laan
Wim Van Criekinge
Tim De Meyer
Simon Denil
G Bea A Wisman
et al.
A1
Journal Article
in
GENES CHROMOSOMES & CANCER
2016
Identification of high-grade prostate cancer using urine-based molecular biomarkers combined with clinical risk factors
Leander Van Neste
Geert Trooskens
Rianne J Hendriks
Jack Schalken
Wim Van Criekinge
C3
Conference
2016
Molecular and epigenetic features of melanomas and tumor immune microenvironment linked to durable remission to ipilimumab-based immunotherapy in metastatic patients
Teofila Seremet
Alexander Koch
Yanina Jansen
Max Schreuer
Sofie Wilgenhof
Véronique Del Marmol
Danielle Liènard
Kris Thielemans
Kelly Schats
Mark Kockx
et al.
A1
Journal Article
in
JOURNAL OF TRANSLATIONAL MEDICINE
2016
RAB25 expression is epigenetically downregulated in oral and oropharyngeal squamous cell carcinoma with lymph node metastasis
MJAM Clausen
LJ Melchers
MF Mastik
L Slagter-Menkema
HJM Groen
BFAM van der Laan
Wim Van Criekinge
Tim De Meyer
Simon Denil
B van der Vegt
et al.
A1
Journal Article
in
EPIGENETICS
2016
Risk score predicts high-grade prostate cancer in DNA-methylation positive, histopathologically negative biopsies
Leander Van Neste
Alan W Partin
Grant D Stewart
Jonathan I Epstein
David J Harrison
Wim Van Criekinge
A1
Journal Article
in
PROSTATE
2016
WRN promoter CpG island hypermethylation does not predict more favorable outcomes for patients with metastatic colorectal cancer treated with irinotecan-based therapy
Linda JW Bosch
Yanxin Luo
Victoria V Lao
Petur Snaebjornsson
Geert Trooskens
Ilse Vlassenbroeck
Sandra Mongera
Weiliang Tang
Piri Welcsh
James G Herman
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2016
2015
Different approaches to measuring gene expression and DNA methylation and their application in cancer research
Alexander Koch
Wim Van Criekinge
Tim De Meyer
Gerben Menschaert
Dissertation
2015
Effect of sunitinib treatment on mutations and methylation in metastatic renal cancer
Grant Stewart
Christophe Van Neste
Alison Meynert
Colin Semple
Finch O'Mahony
Alexander Laird
Alan Mackay
Geert Trooskens
Wim Van Criekinge
Tim De Meyer
et al.
C3
Conference
2015
Epigenetic assay stratifies prostate cancer patients' risk for aggressiveness
Leander Van Neste
Wim Van Criekinge
Joseph Bigley
William E Grizzle
George W Adams
Gary P Kearney
Sandra M Gaston
C3
Conference
2015
Epigenetic profiling of cardiovascular ageing
Simon Denil
Tim De Meyer
Wim Van Criekinge
Sofie Bekaert
Dissertation
2015
Forensic massively parallel sequencing data analysis tool: implementation of MyFLq as a standalone web- and Illumina BaseSpace®-application
Christophe Van Neste
Yannick Gansemans
Dieter De Coninck
David Van Hoofstat
Wim Van Criekinge
Dieter Deforce
Filip Van Nieuwerburgh
A1
Journal Article
in
FORENSIC SCIENCE INTERNATIONAL-GENETICS
2015
Genome-wide DNA methylation detection by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison
Tim De Meyer
Pierre Bady
Geert Trooskens
Sebastian Kurscheid
Jocelyne Bloch
Johan M Kros
Johannes A Hainfellner
Roger Stupp
Mauro Delorenzi
Monika E Hegi
et al.
A1
Journal Article
in
SCIENTIFIC REPORTS
2015
Global DNA methylation analysis of human atherosclerotic plaques reveals extensive genomic hypomethylation and reactivation at imprinted locus 14q32 involving induction of a miRNA cluster
Einari Aavik
Henri Lumivuori
Olli Leppänen
Thomas Wirth
Sanna-Kaisa Häkkinen
Jan-Hinrich Bräsen
Ulrich Beschorner
Thomas Zeller
Maarten Braspenning
Wim Van Criekinge
et al.
A1
Journal Article
in
EUROPEAN HEART JOURNAL
2015
Identification of a predictive signature based on immunohistochemical (IHC), RNA-seq and epigenetic profiling of melanoma metastases for response to ipilimumab-based immunotherapy
Teofila Seremet
Alexander Koch
Sofie Wilgenhof
Max Schreuer
Yanina Jansen
Danielle Lienard
Veronique Del Marmol
Kris Thielemans
Nicolas Van Baren
Pierre Coulie
et al.
C3
Conference
2015
MEXPRESS : visualizing expression, DNA methylation and clinical TCGA data
Alexander Koch
Tim De Meyer
Jana Jeschke
Wim Van Criekinge
A1
Journal Article
in
BMC GENOMICS
2015
Micropeptides as non-classical bioactive peptides in Eukaryotes, a ribosome profiling centered approach
Jeroen Crappé
Wim Van Criekinge
Gerben Menschaert
Geert Baggerman
Dissertation
2015
Mining for viral fragments in methylation enriched sequencing data
Klaas Mensaert
Wim Van Criekinge
Olivier Thas
Ed Schuuring
Renske DM Steenbergen
G Bea A Wisman
Tim De Meyer
A1
Journal Article
in
FRONTIERS IN GENETICS
2015
PROTEOFORMER : deep proteome coverage through ribosome profiling and MS integration
Jeroen Crappé
Elvis Ndah
Alexander Koch
Sandra Steyaert
Daria Fijalkowska
Sarah De Keulenaer
Ellen De Meester
Tim De Meyer
Wim Van Criekinge
Petra Van Damme
et al.
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2015
Porting forensic DNA analysis to deep sequencing
Christophe Van Neste
Dieter Deforce
Wim Van Criekinge
Filip Van Nieuwerburgh
Dissertation
2015
Risk stratification of aggressive prostate cancer based on combined epigenetic and clinical data of men with initial cancer-negative biopsies
Alan W Partin
Leander Van Neste
Grant D Stewart
Joseph Bigley
David J Harrison
Wim Van Criekinge
Jonathan I Epstein
C3
Conference
2015
Spectrin Repeat Containing Nuclear Envelope 1 and Forkhead Box Protein E1 are promising markers for the detection of colorectal cancer in blood
Veerle Melotte
Joo Mi Yi
Marjolein HFM Lentjes
Kim M Smits
Leander Van Neste
Hanneke EC Niessen
Kim AD Wouters
Joost Louwagie
Kornel E Schuebel
James G Herman
et al.
A1
Journal Article
in
CANCER PREVENTION RESEARCH
2015
WRN Promoter CpG island hypermethylation does not predict a favourable outcome for irinotecan-treated metastatic colorectal cancer patients
LJW Bosch
Y Luo
VV Lao
P Snaebjornsson
Geert Trooskens
I Vlassenbroeck
S Mongera
W Tang
P Welcsh
J Herman
et al.
C3
Conference
2015
We are all individuals...: bioinformatics in the personalized medicine era
Leander Van Neste
Wim Van Criekinge
A1
Journal Article
in
CELLULAR ONCOLOGY
2015
2014
A proteogenomics approach integrating proteomics and ribosome profiling increases the efficiency of protein identification and enables the discovery of alternative translation start sites
Alexander Koch
Daria Fijalkowska
Sandra Steyaert
Elvis Ndah
Jeroen Crappé
Sarah De Keulenaer
Ellen De Meester
Ming Ma
Ben Shen
Kris Gevaert
et al.
A1
Journal Article
in
PROTEOMICS
2014
Bacterial diversity assessment in Antarctic terrestrial and aquatic microbial mats : a comparison between bidirectional pyrosequencing and cultivation
Bjorn Tytgat
Elie Verleyen
Dagmar Obbels
Karolien Peeters
Aaike De Wever
Sofie D'hondt
Tim De Meyer
Wim Van Criekinge
Wim Vyverman
Anne Willems
A1
Journal Article
in
PLOS ONE
2014
Clinical validation of an epigenetic assay to predict negative histopathological results in repeat prostate biopsies
Alan W Partin
Leander Van Neste
Eric A Klein
Leonard S Marks
Jason R Gee
Dean A Troyer
Kimberly Rieger-Christ
J Stephen Jones
Cristina Magi-Galluzzi
Leslie A Mangold
et al.
A1
Journal Article
in
JOURNAL OF UROLOGY
2014
Combination of gene copy gain and epigenetic deregulation are associated with the aberrant expression of a stem cell related HOX-signature in glioblastoma
Sebastian Kurscheid
Pierre Bady
Davide Sciuscio
Ivana Samarzija
Tal Shay
Irene Vassallo
Wim Van Criekinge
Eytan Domany
Roger Stupp
Mauro Delorenzi
et al.
C3
Conference
2014
Emerging evidence for CHFR as a cancer biomarker : from tumor biology to precision medicine
Sarah Derks
Arjen HG Cleven
Veerle Melotte
Kim M Smits
Johann C Brandes
Nilofer Azad
Wim Van Criekinge
Adriaan P de Bruïne
James G Herman
Manon van Engeland
A1
Journal Article
in
CANCER AND METASTASIS REVIEWS
2014
Epigenetic profiling of prostate cancer tissue to identify men with high-risk disease
Leander Van Neste
Jeffrey Falk
Ming-Chou Lee
Joseph Bigley
Wim Van Criekinge
E David Crawford
C3
Conference
2014
Evaluation of different methods to assess homologous recombination status and sensitivity to PARP inhibitors in ovarian cancer
A Mukhopadhyay
M Dixon
E Mulligan
H Schuhwerk
J Murray
J Quinn
Leander Van Neste
Wim Van Criekinge
N Curtin
R Edmondson
C3
Conference
2014
Food-derived opioid peptides inhibit cysteine uptake with redox and epigenetic consequences
Malav S Trivedi
Jayni S Shah
Sara Al-Mughairy
Nathaniel W Hodgson
Benjamin Simms
Geert Trooskens
Wim Van Criekinge
Richard C Deth
A1
Journal Article
in
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
2014
Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population
Priscilla Brebi
Leonel Maldonado
Maartje G Noordhuis
Carmen Ili
Pamela Leal
Patricia Garcia
Mariana Brait
Judit Ribas
Christina Michailidi
Jimena Perez
et al.
A1
Journal Article
in
EPIGENETICS
2014
Identification by array comparative genomic hybridization of a new amplicon on chromosome 17q highly recurrent in BRCA1 mutated triple negative breast cancer
Sébastien Toffoli
Isabelle Bar
Fadi Abdel-Sater
Paul Delrée
Pascale Hilbert
Frédéric Cavallin
Fabrice Moreau
Wim Van Criekinge
Magali Lacroix-Triki
Mario Campone
et al.
A1
Journal Article
in
BREAST CANCER RESEARCH
2014
Illumina sequencing of 15 deafness genes using fragmented amplicons
Filip Van Nieuwerburgh
Sarah De Keulenaer
Joachim De Schrijver
Jo Vandesompele
Wim Van Criekinge
Paul Coucke
Dieter Deforce
A2
Journal Article
in
BMC RESEARCH NOTES
2014
Little things make big things happen : a summary of micropeptide encoding genes
Jeroen Crappé
Wim Van Criekinge
Gerben Menschaert
A2
Journal Article
in
EUPA OPEN PROTEOMICS
2014
MEN1 Gene mutation and reduced expression are associated with poor prognosis in pulmonary carcinoids
Dorian RA Swarts
Aldo Scarpa
Vicenzo Corbo
Wim Van Criekinge
Manon van Engeland
Gaia Gatti
Mieke ER Henfling
Mauro Papotti
Aurel Perren
Frans CS Ramaekers
et al.
A1
Journal Article
in
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
2014
Methylation-mediated repression of PRDM14 contributes to apoptosis evasion in HPV-positive cancers
Suzanne Snellenberg
Saskia AGM Cillessen
Wim Van Criekinge
Leontien Bosch
Chris JLM Meijer
Peter JF Snijders
Renske DM Steenbergen
A1
Journal Article
in
CARCINOGENESIS
2014
My-Forensic-Loci-queries (MyFLq) framework for analysis of forensic STR data generated by massive parallel sequencing
Christophe Van Neste
Mado Vandewoestyne
Wim Van Criekinge
Dieter Deforce
Filip Van Nieuwerburgh
A1
Journal Article
in
FORENSIC SCIENCE INTERNATIONAL-GENETICS
2014
N-terminal proteomics and ribosome profiling provide a comprehensive view of the alternative translation initiation landscape in mice and men
Petra Van Damme
Daria Fijalkowska
Wim Van Criekinge
Gerben Menschaert
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2014
Next-generation technologies and data analytical approaches for epigenomics
Klaas Mensaert
Simon Denil
Geert Trooskens
Wim Van Criekinge
Olivier Thas
Tim De Meyer
A1
Journal Article
in
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
2014
On cross-sectional associations of leukocyte telomere length with cardiac systolic, diastolic and vascular function: the Asklepios study
Simon Denil
Ernst Rietzschel
Marc De Buyzere
Caroline Van daele
Patrick Segers
Dirk De Bacquer
Wim Van Criekinge
Sofie Bekaert
Thierry Gillebert
Tim De Meyer
A1
Journal Article
in
PLOS ONE
2014
Promoter CpG island hypermethylation of Decoy Receptor 1 (DCR1) is associated with poor response to irinotecan in metastatic colorectal cancer
L Bosch
G Trooskens
P Snaebjornsson
J Haan
M Koopman
J Tol
T de Meyer
J Louwagie
L Dehaspe
NCT van Grieken
et al.
C3
Conference
2014
SNP-guided identification of monoallelic DNA-methylation events from enrichment-based sequencing data
Sandra Steyaert
Wim Van Criekinge
Ayla De Paepe
Simon Denil
Klaas Mensaert
Katrien Vandepitte
Wim Vanden Berghe
Geert Trooskens
Tim De Meyer
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2014
Strategies for validation and testing of DNA methylation biomarkers
C Noehammer
W Pulverer
MR Hassler
M Hofner
M Wielscher
K Vierlinger
T Liloglou
D McCarthy
TJ Jensen
A Nygren
et al.
A1
Journal Article
in
EPIGENOMICS
2014
Systemic suppression of the shoot metabolism upon rice root nematode infection
Tina Kyndt
Simon Denil
Lander Bauters
Wim Van Criekinge
Tim De Meyer
A1
Journal Article
in
PLOS ONE
2014
2013
Alterations of immune response of non-small lung cancer with azacytidine
John Wrangle
Wei Wang
Alexander Koch
Hariharan Easwaran
Helai P Mohammad
Frank Vendetti
Wim Van Criekinge
Tim De Meyer
Zhengzong Du
Princy Parsana
et al.
A1
Journal Article
in
ONCOTARGET
2013
An epigenomic next-generation sequencing approach to identify predictive markers for PARP inhibitor response in breast cancer cells
Tim De Meyer
Geert Trooskens
Mascha K Wibbe
Sebastian B Bartmann
Manon van Engeland
Wim Van Criekinge
Vivianne C Tjan-Heijnen
Ruth Knüchel
Jürgen Veeck
C3
Conference
2013
An exploration of pathways involved in lung carcinoid progression using gene expression profiling
Dorian RA Swarts
Leander Van Neste
Mieke ER Henfling
Ivo Eijkenboom
Paul P Eijk
Marie-Louise van Velthuysen
Aryan Vink
Marco Volante
Bauke Ylstra
Wim Van Criekinge
et al.
A1
Journal Article
in
CARCINOGENESIS
2013
Association of DNA promoter hypermethylation of decoy receptor 1 (DCR1) with poor response to irinotecan in metastatic colorectal cancer
Wim Van Criekinge
Linda JW Bosch
Geert Trooskens
Peter Snaebjornsson
Josien Haan
Lorraine Cheryl Pelosof
Miriam Koopman
Jolien Tol
Joost Louwagie
Luc Dehaspe
et al.
C3
Conference
2013
CD44 and OTP are strong prognostic markers for pulmonary carcinoids
Dorian RA Swarts
Mieke ER Henfling
Leander Van Neste
Robert Jan van Suylen
Anne-Marie C Dingemans
Winand NM Dinjens
Annick Haesevoets
Martina Rudelius
Erik Thunnissen
Marco Volante
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2013
CD44 and OTP are strong prognostic markers for pulmonary carcinoids
DRA Swarts
M Henfling
L van Neste
R van Suylen
AM Dingemans
WNM Dinjens
A Haesevoets
M Rudelius
FBJ Thunnissen
M Volante
et al.
C3
Conference
2013
CHFR promoter methylation indicates poor prognosis in stage II microsatellite stable colorectal cancer
Manon van Engeland
Arjen Cleven
Sarah Derks
Muriel XG Draht
Kim M Smits
Veerle Melotte
Matty P Weijenberg
James Gordon Herman
Adriaan P de Bruine
Wim Van Criekinge
C3
Conference
2013
Clinical utility of an epigenetic assay to detect occult prostate cancer in histopathologically negative biopsies: results of the MATLOC study
Grant D Stewart
Leander Van Neste
Philippe Delvenne
Paul Delrée
Agnès Delga
S Alan McNeill
Marie O'Donnell
James Clark
Wim Van Criekinge
Joseph Bigley
et al.
A1
Journal Article
in
JOURNAL OF UROLOGY
2013
Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs
Jeroen Crappé
Wim Van Criekinge
Geert Trooskens
Eisuke Hayakawa
Walter Luyten
Geert Baggerman
Gerben Menschaert
A1
Journal Article
in
BMC GENOMICS
2013
Comprehensive analysis of the basal cell carcinoma functional methylome
T Brinkhuizen
S Denil
Geert Trooskens
Wim Van Criekinge
V Winnepenninckx
K Mosterd
M van Engeland
M van Steensel
C3
Conference
2013
Deep proteome coverage based on ribosome profiling aids mass spectrometry-based protein and peptide discovery and provides evidence of alternative translation products and near-cognate translation initiation events
Gerben Menschaert
Wim Van Criekinge
Tineke Notelaers
Alexander Koch
Jeroen Crappé
Kris Gevaert
Petra Van Damme
A1
Journal Article
in
MOLECULAR & CELLULAR PROTEOMICS
2013
Expression of type 2 orexin receptor in human endometrium and its epigenetic silencing in endometrial cancer
P Dehan
C Canon
Geert Trooskens
M Rehli
C Munaut
Wim Van Criekinge
P Delvenne
A1
Journal Article
in
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
2013
GLUCAN SYNTHASE-LIKE8 and STEROL METHYLTRANSFERASE2 are required for ploidy consistency of the sexual reproduction system in Arabidopsis
Nico De Storme
Joachim De Schrijver
Wim Van Criekinge
Vera Wewer
Peter Dörmann
Danny Geelen
A1
Journal Article
in
PLANT CELL
2013
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Ruth Ladenstein
Johannes H. Schulte
Rosa Noguera
Raymond L. Stallings
et al.
C3
Conference
2013
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Ruth Ladenstein
Johannes H Schulte
Rosa Noguera
Raymond L Stallings
et al.
C3
Conference
2013
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Ruth Ladenstein
Johannes H Schulte
Rosa Noguera
Raymond L Stallings
et al.
C3
Conference
2013
Identifying and validating DNA methylation biomarkers: the example of neuroblastoma
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Ruth Ladenstein
Johannes H Schulte
Rosa Noguera
Raymond L Stallings
et al.
C3
Conference
2013
Mass spectrometry and ribosome profiling, a perfect combination towards a more comprehensive identification strategy of true in vivo protein forms
Jeroen Crappé
Alexander Koch
Sandra Steyaert
Wim Van Criekinge
Petra Van Damme
Gerben Menschaert
C3
Conference
2013
Methylation-specific digital karyotyping of HPV16E6E7 expressing human keratinocytes identifies novel methylation events in cervical carcinogenesis
Renske DM Steenbergen
Maté Ongenaert
Suzanne Snellenberg
Geert Trooskens
Wendy F van der Meide
Deeksha Pandey
Noga Bloushtain-Qimron
Kornelia Polyak
Chris JLM Meijer
Peter JF Snijders
et al.
A1
Journal Article
in
JOURNAL OF PATHOLOGY
2013
Micropeptides, the next best thing after micro-RNA? Combining in silico prediction and ribosome profiling in a genome-wide search for novel micropeptides
Jeroen Crappé
Geert Trooskens
Eisuke Hayakawa
Walter Luyten
Geert Baggerman
Wim Van Criekinge
Gerben Menschaert
C3
Conference
2013
Prediction of risk for prostate cancer in histopathologically negative biopsies by multigene epigenetic assay
Leander Van Neste
Wim Van Criekinge
Olivier Thas
Joseph Bigley
Grant Duncan Stewart
David James Harrison
C3
Conference
2013
Quality evaluation of methyl binding domain based kits for enrichment DNA-methylation sequencing
Tim De Meyer
Evi Mampaey
Michaël Vlemmix
Simon Denil
Geert Trooskens
Jean-Pierre Renard
Sarah De Keulenaer
Pierre Dehan
Gerben Menschaert
Wim Van Criekinge
A1
Journal Article
in
PLOS ONE
2013
Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue : a preliminary study
Claudina Perez Novo
Yuan Zhang
Simon Denil
Geert Trooskens
Tim De Meyer
Wim Van Criekinge
Paul Van Cauwenberge
Luo Zhang
Claus Bachert
A1
Journal Article
in
ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY
2013
The CpG island methylator phenotype: what's in a name?
Laura AE Hughes
Veerle Melotte
Joachim De Schrijver
Michiel de Maat
Vincent THBM Smit
Judith VMG Bovée
Pim J French
Piet A van den Brandt
Leo J Schouten
Tim De Meyer
et al.
A1
Journal Article
in
CANCER RESEARCH
2013
The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer
Kevin Sharpe
Grant D Stewart
Alan Mackay
Christophe Van Neste
Charlotte Rofe
Dan Berney
Irfan Kayani
Axel Bex
Elaine Wan
Fiach C O'Mahony
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2013
Transcriptional analysis through RNA sequencing of giant cells induced by Meloidogyne graminicola in rice roots
Hongli Ji
Godelieve Gheysen
Simon Denil
Keith Lindsey
Jennifer F Topping
Kamrun Nahar
Annelies Haegeman
Winnok De Vos
Geert Trooskens
Wim Van Criekinge
et al.
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL BOTANY
2013
2012
A tissue biopsy-based epigenetic multiplex PCR assay for prostate cancer detection
Leander Van Neste
Joseph Bigley
Adam Toll
Gaëtan Otto
James Clark
Paul Delrée
Wim Van Criekinge
Jonathan I Epstein
A1
Journal Article
in
BMC UROLOGY
2012
An omnibus consistent adaptive percentile modified Wilcoxon rank sum test with applications in gene expression studies
Olivier Thas
Lieven Clement
John Rayner
Beatriz Carvalho
Wim Van Criekinge
A1
Journal Article
in
BIOMETRICS
2012
Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen
Jana Jeschke
Leander Van Neste
Sabine C Glöckner
Mashaal Dhir
Marilia Freitas Calmon
Valerie Deregowski
Wim Van Criekinge
Ilse Vlassenbroeck
Alexander Koch
Timothy A Chan
et al.
A1
Journal Article
in
EPIGENETICS
2012
Colorectal adenoma to carcinoma progression is accompanied by changes in gene expression associated with ageing, chromosomal instability, and fatty acid metabolism.
Beatriz Carvalho
Anke H Sillars-Hardebol
Cindy Postma
Sandra Mongera
Jochim Terhaar Sive Droste
Askar Obulkasim
Mark van de Wiel
Wim Van Criekinge
Bauke Ylstra
Remond JA Fijneman
et al.
A1
Journal Article
in
CELLULAR ONCOLOGY
2012
DNA methylation of phosphatase and actin regulator 3 detects colorectal cancer in stool and complements FIT
Linda JW Bosch
Frank A Oort
Maarten Neerincx
Carolina AJ Khalid-de Bakker
Jochim S Terhaar sive Droste
Veerle Melotte
Daisy MAE Jonkers
Ad AM Masclee
Sandra Mongera
Madeleine Grooteclaes
et al.
A1
Journal Article
in
CANCER PREVENTION RESEARCH
2012
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Ruth Ladenstein
Johannes H Schulte
Rosa Noguera
Raymond L Stallings
et al.
A1
Journal Article
in
GENOME BIOLOGY
2012
Genome‐wide RNA‐ and MBD‐sequencing in HCT116 and DKO cells as a global re‐expression model
Joachim De Schrijver
Geert Trooskens
Linda JW Bosch
Pierre Dehan
Beatriz Carvalho
Leander Van Neste
Gerrit Meijer
Steve Baylin
Wim Van Criekinge
C3
Conference
2012
Identification of new molecular species using second-generation sequencing
Joachim De Schrijver
Wim Van Criekinge
Sofie Bekaert
Dissertation
2012
Improved base-calling and quality scores for 454 sequencing based on a Hurdle Poisson model
Kristof De Beuf
Joachim De Schrijver
Olivier Thas
Wim Van Criekinge
Rafael A Irizarry
Lieven Clement
A1
Journal Article
in
BMC BIOINFORMATICS
2012
Low dose irradiation of thyroid cells reveals a unique transcriptomic and epigenetic signature in RET/PTC-positive cells
Khalil Abou-El-Ardat
Pieter Monsieurs
Nataša Anastasov
Mike Atkinson
Hanane Derradji
Tim De Meyer
Sofie Bekaert
Wim Van Criekinge
Sarah Baatout
A1
Journal Article
in
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
2012
Micropeptides, the next best thing after micro-RNA?: combining in silico prediction and ribosome profiling in a genome-wide search for novel micropeptides
Jeroen Crappé
Geert Trooskens
Eisuke Hayakawa
Walter Luyten
Geert Baggerman
Wim Van Criekinge
Gerben Menschaert
C3
Conference
2012
Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform
Sarah De Keulenaer
Jan Hellemans
Steve Lefever
Jean-Pierre Renard
Joachim De Schrijver
Hendrik Van de Voorde
Mohammad Amin Tabatabaiefar
Filip Van Nieuwerburgh
Daisy Flamez
Filip Pattyn
et al.
A1
Journal Article
in
BMC MEDICAL GENOMICS
2012
Promoter methylation analysis identifies prognostic methylation biomarkers in neuroblastoma
Anneleen Decock
Maté Ongenaert
Jasmien Hoebeeck
Katleen De Preter
Gert Van Peer
Wim Van Criekinge
Ruth Ladenstein
Johannes H Schulte
Rosa Noguera
Raymond L Stallings
et al.
C3
Conference
2012
Spectral clustering in peptidomics studies allows homology searching and modification profiling: HomClus, a versatile tool
Gerben Menschaert
Eisuke Hayakawa
Liliane Schoofs
Wim Van Criekinge
Geert Baggerman
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2012
The epigenetic promise for prostate cancer diagnosis.
Leander Van Neste
James G Herman
Gaëtan Otto
Joseph W Bigley
Jonathan I Epstein
Wim Van Criekinge
A1
Journal Article
in
PROSTATE
2012
Transcriptional reprogramming by root knot and migratory nematode infection in rice
Tina Kyndt
Simon Denil
Annelies Haegeman
Geert Trooskens
Lander Bauters
Wim Van Criekinge
Tim De Meyer
Godelieve Gheysen
A1
Journal Article
in
NEW PHYTOLOGIST
2012
Transcriptome analysis of rice mature root tissue and root tips in early development by massive parallel sequencing
Tina Kyndt
Simon Denil
Annelies Haegeman
Geert Trooskens
Tim De Meyer
Wim Van Criekinge
Godelieve Gheysen
A1
Journal Article
in
JOURNAL OF EXPERIMENTAL BOTANY
2012
2011
A non-parametric method to assess the presence of significant DNA-methylation in enrichment-based NGS data
Klaas Mensaert
Geert Trooskens
Wim Van Criekinge
Olivier Thas
Tim De Meyer
C3
Conference
2011
Accurate long read mapping using enhanced suffix arrays
Michaël Vyverman
Joachim De Schrijver
Wim Van Criekinge
Peter Dawyndt
Veerle Fack
P1
Conference
2011
Applying massive parallel sequencing to molecular diagnosis of Marfan and Loeys-Dietz syndromes
Machteld Baetens
Lut Van Laer
Kim De Leeneer
Jan Hellemans
Joachim De Schrijver
Hendrik Van de Voorde
Marjolijn Renard
Hal Dietz
Ronald V Lacro
Björn Menten
et al.
A1
Journal Article
in
HUMAN MUTATION
2011
Charting the methylome
Geert Trooskens
Tim De Meyer
Simon Denil
Wim Van Criekinge
C3
Conference
2011
Epigenetic, metabolic and signal transduction pathways involved in radiation response of normal and transformed thyrocytes
Khalil Abouelaradat
Wim Van Criekinge
Sarah Baatout
Tim De Meyer
Sofie Bekaert
Dissertation
2011
Genome sequence of Helicobacter suis supports its role in gastric pathology
Miet Vermoote
Tom Vandekerckhove
Bram Flahou
Frank Pasmans
Annemieke Smet
Dominic De Groote
Wim Van Criekinge
Richard Ducatelle
Freddy Haesebrouck
C3
Conference
2011
Genome sequence of Helicobacter suis supports its role in gastric pathology
Miet Vermoote
Tom Vandekerckhove
Bram Flahou
Frank Pasmans
Annemieke Smet
Dominic De Groote
Wim Van Criekinge
Richard Ducatelle
Freddy Haesebrouck
A1
Journal Article
in
VETERINARY RESEARCH
2011
Massive parallel amplicon sequencing of the breast cancer genes BRCA1 and BRCA2: opportunities, challenges, and limitations
Kim De Leeneer
Jan Hellemans
Joachim De Schrijver
Machteld Baetens
Bruce Poppe
Wim Van Criekinge
Anne De Paepe
Paul Coucke
Kathleen Claes
A1
Journal Article
in
HUMAN MUTATION
2011
Micro peptides as a new class of bio-active peptides in Eukaryotes
Jeroen Crappé
Gerben Menschaert
Geert Trooskens
Joachim De Schrijver
Geert Baggerman
Wim Van Criekinge
C3
Conference
2011
MutaDATABASE: a centralized and standardized DNA variation database
Sherri Bale
Martijn Devisscher
Wim Van Criekinge
Heidi L Rehm
Frederik Decouttere
Robert Nussbaum
Johan T Dunnen
Patrick Willems
A1
Journal Article
in
NATURE BIOTECHNOLOGY
2011
PROKAR‐SEQ: an analysis and visualization framework for next‐generation sequencing based quantification of prokaryotic communities
Joachim De Schrijver
Pieter-Jan Volders
Frederiek-Maarten Kerckhof
Dagmar Obbels
Elie Verleyen
Wim Vyverman
Tim De Meyer
Wim Van Criekinge
C3
Conference
2011
Practical tools to implement massive parallel pyrosequencing of PCR products in next generation molecular diagnostics
Kim De Leeneer
Joachim De Schrijver
Lieven Clement
Machteld Baetens
Steve Lefever
Sarah De Keulenaer
Wim Van Criekinge
Dieter Deforce
Filip Van Nieuwerburgh
Sofie Bekaert
et al.
A1
Journal Article
in
PLOS ONE
2011
Response to low-dose X-irradiation is p53-dependent in a papillary thyroid carcinoma model system
Khalil Abou-El-Ardat
Hanane Derradji
Winnok De Vos
Tim De Meyer
Sofie Bekaert
Wim Van Criekinge
Sarah Baatout
A1
Journal Article
in
INTERNATIONAL JOURNAL OF ONCOLOGY
2011
Telomere length and cardiovascular aging: the means to the ends?
Tim De Meyer
Ernst Rietzschel
Marc De Buyzere
Wim Van Criekinge
Sofie Bekaert
A1
Journal Article
in
AGEING RESEARCH REVIEWS
2011
2010
A hybrid, de novo based, genome-wide database search approach applied to the sea urchin neuropeptidome
Gerben Menschaert
Tom Vandekerckhove
Geert Baggerman
Bart Landuyt
Jonathan V Sweedler
Liliane Schoofs
Walter Luyten
Wim Van Criekinge
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2010
Accurate long read mapping using enhanced suffix arrays
Michaël Vyverman
Joachim De Schrijver
Wim Van Criekinge
Peter Dawyndt
Veerle Fack
C3
Conference
2010
Analysing 454 amplicon resequencing experiments using the modular and database oriented Variant Identification Pipeline
Joachim De Schrijver
Kim De Leeneer
Steve Lefever
Nick Sabbe
Filip Pattyn
Filip Van Nieuwerburgh
Paul Coucke
Dieter Deforce
Jo Vandesompele
Sofie Bekaert
et al.
A1
Journal Article
in
BMC BIOINFORMATICS
2010
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells
Joyce E Ohm
Prashant Mali
Leander Van Neste
David M Berman
Liang Liang
Kurinji Pandiyan
Kimberley J Briggs
Wei Zhang
Pedram Argani
Brian Simons
et al.
A1
Journal Article
in
CANCER RESEARCH
2010
Evaluation of standard and advanced preprocessing methods for the univariate analysis of blood serum 1H-NMR spectra
Tim De Meyer
Davy Sinnaeve
Björn Van Gasse
Ernst Rietzschel
Marc De Buyzere
Michel Langlois
Sofie Bekaert
José Martins
Wim Van Criekinge
A1
Journal Article
in
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
2010
Exploring 3D pooled next-generation sequencing using SNP-Cub^3
Joachim De Schrijver
Bram De Wilde
Geert Trooskens
Jo Vandesompele
Wim Van Criekinge
C3
Conference
2010
GULP1, a potential tumor suppressor gene in ovarian tumors and its utility as a biomarker
Leonel Maldonado
Mariana Brait
Shahnaz Begum
Aditi Chatterjee
Myriam Loyo
Alvaro Barbosa
M Luana Poeta
Vito M Fazio
Angioli Roberto
Elisabetta Tarquini
et al.
C3
Conference
2010
Genome sequence of Helicobacter suis supports its role in gastric pathology
Miet Vermoote
Tom Vandekerckhove
Bram Flahou
Frank Pasmans
Annemieke Smet
Dominic De Groote
Wim Van Criekinge
Richard Ducatelle
Freddy Haesebrouck
C3
Conference
2010
Identification and validation of the methylated TWIST1 and NID2 genes through real-time methylation-specific polymerase chain reaction assays for the noninvasive detection of primary bladder cancer in urine samples
Isabelle Renard
Steven Joniau
Ben van Cleynenbreugel
Catherine Collette
Christophe Naômé
Ilse Vlassenbroeck
Hubert Nicolas
Jean de Leval
Josef Straub
Wim Van Criekinge
et al.
A2
Journal Article
in
EUROPEAN UROLOGY
2010
Mining cleavage sites of the mouse peptidome
Kurt De Grave
Tias Guns
Tom Vandekerckhove
Bart Landuyt
Gerben Menschaert
Wim Van Criekinge
Liliane Schoofs
Walter Luyten
C3
Conference
2010
Peptidomics coming of age : a review of contributions from a bioinformatics angle
Gerben Menschaert
Tom Vandekerckhove
Geert Baggerman
Liliane Schoofs
Walter Luyten
Wim Van Criekinge
A1
Journal Article
in
JOURNAL OF PROTEOME RESEARCH
2010
The N-myc downstream regulated gene (NDRG) family: diverse functions, multiple applications
Veerle Melotte
Xianghu Qu
Maté Ongenaert
Wim Van Criekinge
Adriaan P de Bruine
H Scott Baldwin
Manon van Engeland
A1
Journal Article
in
FASEB JOURNAL
2010
2009
A plasma-based colorectal cancer (CRC) screening assay using DNA methylation markers: first results of multicenter studies
J Louwagie
W Pommerien
G Brichard
G Otto
Wim Van Criekinge
SB Baylin
N Ahuja
HP Adams
D Nurnberg
K Bierau
C3
Conference
2009
Bioinformatics solutions for MS/MS interpretation tailored to the peptidomics field
Gerben Menschaert
Tom Vandekerckhove
Geert Baggerman
Bart Landuyt
Liliane Schoofs
Walter Luyten
Wim Van Criekinge
A4
Journal Article
in
COMMUNICATIONS IN AGRICULTURAL AND APPLIED BIOLOGICAL SCIENCES
2009
Cellular reprogramming
Maté Ongenaert
Wim Van Criekinge
Dissertation
2009
E2Fs mediate a fundamental cell-cycle deregulation in high-grade serous ovarian carcinomas
Tim De Meyer
Ingrid TGW Bijsmans
Koen Van de Vijver
Sofie Bekaert
Jan Oosting
Wim Van Criekinge
Manon van Engeland
Nathalie LG Sieben
A1
Journal Article
in
JOURNAL OF PATHOLOGY
2009
External X-irradiation causes a decrease in the proliferation of two papillary thyroid carcinoma cell lines with no significant increase in cell death
Khalil Abou-El-Ardat
Hanane Derradji
Sofie Bekaert
Tim De Meyer
Wim Van Criekinge
Sarah Baatout
C3
Conference
2009
GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer
Debby MEI Hellebrekers
Marjolein HFM Lentjes
Sandra M van den Bosch
Veerle Melotte
Kim AD Wouters
Kathleen LJ Daenen
Kim M Smits
Yohimitsu Akiyama
Yasuhito Yuasa
Silvia Sanduleanu
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2009
Pharmacologic unmasking of epigenetically silenced genes in breast cancer
Kimberley Laskie Ostrow
Hannah Lui Park
Mohammad Obaidul Hoque
Myoung Sook Kim
Jun Wei Liu
Pedral Argani
William Westra
Wim Van Criekinge
David Sidransky
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2009
Prognostic significance of Gremlin1 (GREM1) promoter CPG island hypermethylation in clear cell renal cell carcinoma
Iris JH van Vlodrop
Marcella Baldewijns
Kim Smits
Leo Schouten
Leander Van Neste
Wim Van Criekinge
Hein van Poppel
Evelyne Lerut
Nita Ahuja
James Herman
et al.
C3
Conference
2009
Promoter DNA methylation of Oncostatin M receptor-β as a novel diagnostic and therapeutic marker in colon cancer
Myoung Sook Kim
Joost Louwagie
Beatriz Carvalho
Jochim S Terhaar Sive Droste
Hannah Lui Park
Young Kwang Chae
Keishi Yamashita
Jun Wei Liu
Kimberley Laski Ostrow
Shizhang Ling
et al.
A1
Journal Article
in
PLOS ONE
2009
Promoter hypermethylation of Phactr3, a potential new biomarker for colorectal cancer detection
Linda Bosch
Maarten Neerincx
Frank Oort
Sandra Mongera
Ad Masclee
Daisy Jonkers
Carolina Khalid-de Bakker
Katja Bierau
Wim Van Criekinge
Adriaan de Bruine
et al.
C3
Conference
2009
Spectral clustering in peptidomics studies helps to unravel modification profile of biologically active peptides and enhances peptide identification rate
Gerben Menschaert
Tom Vandekerckhove
Bart Landuyt
Eisuke Hayakawa
Liliane Schoofs
Walter Luyten
Wim Van Criekinge
A1
Journal Article
in
PROTEOMICS
2009
Systemic telomere length and preclinical atherosclerosis : the Asklepios study
Tim De Meyer
Ernst Rietzschel
Marc De Buyzere
Michel Langlois
Dirk De Bacquer
Patrick Segers
PIET VAN DAMME
Gui De Backer
Patric Van Oostveldt
Wim Van Criekinge
et al.
A1
Journal Article
in
EUROPEAN HEART JOURNAL
2009
VIP and VIP Validator: a diagnostic amplicon sequencing Variant Interpretation Pipeline and variant detection validator
Joachim De Schrijver
Wim Van Criekinge
C3
Conference
2009
2008
Bioinformatic strategies for more complete and accurate identification of neuropeptides
Timothy A. Richmond
Geert Baggerman
Tom Vandekerckhove
Gerben Menschaert
Steven Husson
Peter Verleyen
Liliane Schoofs
Wim Van Criekinge
C3
Conference
2008
Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells
KM MCGARVEY
Leander Van Neste
L COPE
JE OHM
JG HERMANN
Wim Van Criekinge
KE SCHUEBEL
SB BAYLIN
A1
Journal Article
in
CANCER RESEARCH
2008
Discovery of DNA methylation markers in cervical cancer using relaxation ranking
Maté Ongenaert
G Bea A Wisman
Haukeline H Volders
Alice J Koning
Ate GJ van der Zee
Wim Van Criekinge
Ed Schuuring
A1
Journal Article
in
BMC MEDICAL GENOMICS
2008
GATA4 and GATA5 act as tumor suppressors and are potential biomarkers in colorectal cancer
Debby Hellebrekers
Marjolein Lentjes
Sandra van den Bosch
Kim Wouters
Kathleen Daenen
Veerle Melotte
Kim Smits
Iris Partouns-Hendriks
Yoshimitsu Akiyama
Yasuhito Yuasa
et al.
C3
Conference
2008
Genome-wide promoter analysis uncovers portions of the cancer methylome
MO HOQUE
MS KIM
KL OSTROW
J LIU
GBA WISMAN
HL PARK
ML POETA
C JERONIMO
R HENRIQUE
A LENDVAI
et al.
A1
Journal Article
in
CANCER RESEARCH
2008
Genrisk-T project: response of the TPC-1 papillary thyroid carcinoma cell line to a range of low to high doses of irradiation
K Abou-El-Ardat
H Derradji
Sofie Bekaert
Tim De Meyer
Wim Van Criekinge
S Baatout
A4
Journal Article
in
COMMUNICATIONS IN AGRICULTURAL AND APPLIED BIOLOGICAL SCIENCES
2008
Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer
Jun-Wei Liu
Jatin K Nagpal
Carmen Jeronimo
Ji Eun Lee
Rui Henrique
Myoung Sook Kim
Kimberley L Ostrow
Keishi Yamashita
Wim Van Criekinge
Guojun Wu
et al.
A1
Journal Article
in
PROSTATE
2008
Integration of DNA and expression microarray data unravels seven putative oncogenes on 20Q amplicon involved in colorectal adenoma to carcinoma progression
Beatriz Carvalho
Cindy Postma
Sandra Mongera
Erik Hopmans
Sharon Diskin
Mark van de Wiel
Wim Van Criekinge
Olivier Thas
Anja Mathhai
Miguel Cuesta
et al.
C3
Conference
2008
Lower red blood cell counts in middle-aged subjects with shorter peripheral blood leukocyte telomere length
Tim De Meyer
Marc De Buyzere
Michel Langlois
Ernst Rietzschel
Peter Cassiman
Dirk De Bacquer
Patric Van Oostveldt
Gui De Backer
Thierry Gillebert
Wim Van Criekinge
et al.
A1
Journal Article
in
AGING CELL
2008
Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression
B Carvalho
C Postma
S Mongera
E Hopmans
S Diskin
MA van de Wiel
Wim Van Criekinge
Olivier Thas
A Mathhai
MA Cuesta
et al.
A1
Journal Article
in
GUT
2008
NMR-based characterization of metabolic alterations in hypertension using an adaptive, intelligent binning algorithm
Tim De Meyer
Davy Sinnaeve
Björn Van Gasse
Elena Tsiporkova
Ernst Rietzschel
Marc De Buyzere
Thierry Gillebert
Sofie Bekaert
José Martins
Wim Van Criekinge
A1
Journal Article
in
ANALYTICAL CHEMISTRY
2008
PubMeth : a cancer methylation database combining text-mining and expert annotation
Maté Ongenaert
Leander Van Neste
Tim De Meyer
Gerben Menschaert
Sofie Bekaert
Wim Van Criekinge
A1
Journal Article
in
NUCLEIC ACIDS RESEARCH
2008
Pubmeth: reviewed methylation database in cancer based on text-mining
Maté Ongenaert
Leander Van Neste
Tim De Meyer
Gerben Menschaert
Sofie Bekaert
Wim Van Criekinge
C1
Conference
2008
Studying telomeres in a longitudinal population based study
Tim De Meyer
Ernst Rietzschel
Marc De Buyzere
Wim Van Criekinge
Sofie Bekaert
A1
Journal Article
in
Frontiers in Bioscience
2008
The biomarker potential of promoter hypermethylation in HNSCC treated by radiotherapy
Harlinde De Schutter
Wim Van Criekinge
Sandra Nuyts
C3
Conference
2008
ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer
Jun-Wei Liu
Jatin K Nagpal
Wenyue Sun
Juna Lee
Myoung Sook Kim
Kimberley L Ostrow
Shaoyu Zhou
Carmen Jeronimo
Rui Henrique
Wim Van Criekinge
et al.
A1
Journal Article
in
CLINICAL CANCER RESEARCH
2008
2007
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer
KE SCHUEBEL
W CHEN
L COPE
SC GLOCKNER
H SUZUKI
JM YI
TA CHAN
Leander Van Neste
Wim Van Criekinge
S VAN DEN BOSCH
et al.
A1
Journal Article
in
PLOS GENETICS
2007
Discovery of methylation markers using a relaxation ranking algorithm
Maté Ongenaert
Wim Van Criekinge
J STRAUB
A VAN DER ZEE
E SCHUURING
H SPOLDERS
B WISMAN
C1
Conference
2007
Genome wide promoter methylation analysis in neuroblastoma with perspectives for integrated molecular profiling
Jasmien Hoebeeck
Maté Ongenaert
Evi Michels
Katleen De Preter
Joëlle Vermeulen
Nurten Yigit
Anne De Paepe
Wim Van Criekinge
Franki Speleman
Jo Vandesompele
C3
Conference
2007
Identification of epigenetically silenced genes in tumor endothelial cells
Debby MEI Hellebrekers
Veerle Melotte
Emmanuelle Viré
Elise Langenkamp
Grietje Molema
François Fuks
James G Herman
Wim Van Criekinge
Arjan W Griffioen
Manon Van Engeland
A1
Journal Article
in
CANCER RESEARCH
2007
Paternal age at birth is an important determinant of offspring telomere length
Tim De Meyer
Ernst Rietzschel
Marc De Buyzere
Dirk De Bacquer
Wim Van Criekinge
Gui De Backer
Thierry Gillebert
Patric Van Oostveldt
Sofie Bekaert
A1
Journal Article
in
HUMAN MOLECULAR GENETICS
2007
Radiosensitization by histone deacetylase inhibitors +/- demethylating agents in head and neck cancer cell lines
Harlinde De Schuller
Wim Van Criekinge
Sandra Nuyts
C3
Conference
2007
SOS MS : enhancements for Mascot Search engine and other mass spectrometry software
Tom Vandekerckhove
Gerben Menschaert
Bart Landuyt
Kurt Boonen
Wim Van Criekinge
C3
Conference
2007
Telomere length and cardiovascular risk factors in a middle-aged population free of overt cardiovascular disease
Sofie Bekaert
Tim De Meyer
Ernst Rietzschel
Marc De Buyzere
Dirk De Bacquer
Michel Langlois
Patrick Segers
Luc Cooman
Piet Van Damme
Peter Cassiman
et al.
A1
Journal Article
in
AGING CELL
2007
2006
Detection of putative secreted proteins in the plant-parasitic nematode Heterodera schachtii
Bartel Vanholme
M Mitreva
Wim Van Criekinge
Marc Logghe
D Bird
JP McCarter
Godelieve Gheysen
A1
Journal Article
in
PARASITOLOGY RESEARCH
2006
Informatica in dienst van de biotechnologie
Wim Van Criekinge
A4
Journal Article
in
HET INGENIEURSBLAD
2006
Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection
MO HOQUE
S BEGUM
O TOPALOGLU
A CHATTERJEE
E ROSENBAUM
Wim Van Criekinge
WH WESTRA
M SCHOENBERG
M ZAHURAK
SN GOODMAN
et al.
A1
Journal Article
in
JOURNAL OF THE NATIONAL CANCER INSTITUTE
2006
2005
CpG island characterisation
Maté Ongenaert
Wim Van Criekinge
C1
Conference
2005
Phylogenetic trees: visualizing, customizing and detecting incongruence
Geert Trooskens
David De Beule
Frederik Decouttere
Wim Van Criekinge
A1
Journal Article
in
BIOINFORMATICS
2005
Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects
MO HOQUE
O TOPALOGLU
S BEGUM
R HENRIQUE
E ROSENBAUM
Wim Van Criekinge
WH WESTRA
D SIDRANSKY
A1
Journal Article
in
JOURNAL OF CLINICAL ONCOLOGY
2005
2004
A new class of ubiquitin extension proteins secreted by the dorsal pharyngeal gland in plant parasitic cyst nematodes
Tom Tytgat
Bartel Vanholme
Jan De Meutter
Myriam Claeys
Marjolein Couvreur
Isabelle Vanhoutte
Greetje Gheysen
Wim Van Criekinge
Gaetan Borgonie
August Coomans
et al.
A1
Journal Article
in
MOLECULAR PLANT-MICROBE INTERACTIONS
2004
The yeast three-hybrid system as a tool to study caspases
Wim Van Criekinge
Peter Schotte
Karen Heyninck
Rudi Beyaert
Bookchapter
in
Apoptosis methods and protocols
2004
2001
Phagocytes: the professional and amateur disposal experts of apoptosis
Elke Smits
Wim Van Criekinge
A4
Journal Article
in
ELSO GAZETTE
2001
2000
Bioinformatics: the goldrush
Wim Van Criekinge
A4
Journal Article
in
MEDEDELINGEN VAN DE FACULTEIT LANDBOUWKUNDIGE EN TOEGEPASTE BIOLOGISCHE WETENSCHAPPEN, UNIVERSITEIT GENT
2000
Identification and characterization of a dimerization domain in CED-6, an adapter protein involved in engulfment of apoptotic cells
Hua Poo Su
Enrico Brugnera
Wim Van Criekinge
Elke Smits
Michael Hengartner
Thierry Bogaert
Kodimangalam S Ravichandran
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
2000
Identification and characterization of a dimerization domain in CED-6, an adapter protein involved in engulfment of apoptotic cells
Hua Poo Su
Enrico Brugnera
Wim Van Criekinge
Elke Smits
Michael Hengartner
Thierry Bogaert
Kodimangalam S Ravichandran
C3
Conference
2000
1999
Alzheimer's disease associated presenilin 1 interacts with HC5 and ZETA, subunits of the catalytic 20S proteasome.
G VAN GASSEN
C DE JONGHE
S PYPE
Wim Van Criekinge
A JULLIAMS
I VANDERHOEVEN
S WOODROW
Rudi Beyaert
D HUYLEBROECK
C VAN BROECKHOVEN
A1
Journal Article
in
NEUROBIOLOGY OF DISEASE
1999
GAL4 is a substrate for caspases : implications for two-hybrid screening and other GAL4-based assays
Wim Van Criekinge
Sigrid Cornelis
Marc Van De Craen
Peter Vandenabeele
Walter Fiers
Rudi Beyaert
A2
Journal Article
in
MOLECULAR CELL BIOLOGY RESEARCH COMMUNICATIONS
1999
Identification of caspases that cleave presenilin-1 and presenilin-2 - Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.
Marc Van De Craen
C DE JONGHE
I VAN DEN BRANDE
Wim Declercq
G VAN GASSEN
Wim Van Criekinge
I VANDERHOEVEN
Walter Fiers
C VAN BROECKHOVEN
L HENDRIKS
et al.
A1
Journal Article
in
FEBS LETTERS
1999
The human homologue of Caenorhabditis elegans CED-6 specifically promotes phagocytosis of apoptotic cells
Elke Smits
Wim Van Criekinge
Geert Plaetinck
Thierry Bogaert
A1
Journal Article
in
CURRENT BIOLOGY
1999
The zinc finger protein A20 inhibits TNF-induced NF-kappa B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappa B-inhibiting protein ABIN.
Karen Heyninck
Dirk De Valck
Wim Vanden Berghe
Wim Van Criekinge
Roland Contreras
Walter Fiers
Guy Haegeman
Rudi Beyaert
A1
Journal Article
in
JOURNAL OF CELL BIOLOGY
1999
Yeast two-hybrid : state of the art
Wim Van Criekinge
Rudi Beyaert
A2
Journal Article
in
BIOLOGICAL PROCEDURES ONLINE
1999
1998
Cathepsin B-mediated activation of the proinflammatory caspase-11
Peter Schotte
Wim Van Criekinge
Marc Van De Craen
Geert van Loo
Marjory Desmedt
Johan Grooten
Maria Cornelissen
Leo De Ridder
Joël Vandekerckhove
Walter Fiers
et al.
A1
Journal Article
in
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
1998
Identification of a new caspase homologue: caspase-14.
Marc Van De Craen
Geert van Loo
S PYPE
Wim Van Criekinge
I VAN DEN BRANDE
Francis Molemans
Walter Fiers
Wim Declercq
Peter Vandenabeele
A1
Journal Article
in
CELL DEATH AND DIFFERENTIATION
1998
Is er leven na de (cel)dood?
Wim Van Criekinge
Elke Smits
Christian Paul G. Burvenich
Rudi Beyaert
A2
Journal Article
in
VLAAMS DIERGENEESKUNDIG TIJDSCHRIFT
1998
Karakterisering van caspasen in een '2 en 3-hybrid'-systeem
Wim Van Criekinge
Rudi Beyaert
Walter Fiers
Roland Contreras
Dissertation
1998
Use of the yeast three-hybrid system as a tool to study caspases.
Wim Van Criekinge
Maria (Marjan) van Gurp
Els Decoster
Peter Schotte
Marc Van De Craen
Walter Fiers
Peter Vandenabeele
Rudi Beyaert
A1
Journal Article
in
ANALYTICAL BIOCHEMISTRY
1998
1997
A20 inhibits NF-kappa B activation independently of binding to 14-3-3 proteins.
Dirk De Valck
Karen Heyninck
Wim Van Criekinge
Peter Vandenabeele
Walter Fiers
Rudi Beyaert
A1
Journal Article
in
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
1997
Characterization of seven murine caspase family members
Marc Van de Craen
Peter Vandenabeele
Wim Declercq
Ilse Van den Brande
Geert van Loo
Francis Molemans
Peter Schotte
Wim Van Criekinge
Rudi Beyaert
Walter Fiers
A1
Journal Article
in
FEBS LETTERS
1997
Presenilins and Alzheimer's disease: identification of proteins that interact with presenilin I using the yeast two-hybrid system
Geert Van Gassen
Wim Van Criekinge
Rudi Beyaert
Jurgen Del-Favero
Christine Van Broeckhoven
M Cruts
A2
Journal Article
in
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
1997
1996
A20, an inhibitor of cell death, self-associates by its zinc finger domain.
Dirk De Valck
Karen Heyninck
Wim Van Criekinge
Roland Contreras
Rudi Beyaert
Walter Fiers
A1
Journal Article
in
FEBS LETTERS
1996
Functional characterization of the prodomain of interleukin-1 beta-converting enzyme.
Wim Van Criekinge
Rudi Beyaert
M VANDECRAEN
Peter Vandenabeele
Peter Schotte
D DEVALCK
Walter Fiers
A1
Journal Article
in
JOURNAL OF BIOLOGICAL CHEMISTRY
1996
TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis.
Walter Fiers
Rudi Beyaert
Elke Boone
Sigrid Cornelis
Wim Declercq
Els Decoster
Geertrui Denecker
Bart Depuydt
Dirk De Valck
G DEWILDE
et al.
A1
Journal Article
in
JOURNAL OF INFLAMMATION
1996
1995
Intraliposomale precipitatie: de natuur als leermeester
Wim Van Criekinge
Paul Van der Meeren
A4
Journal Article
in
HET INGENIEURSBLAD
1995
On-line simulation as a methodology to recover size distributions from dynamic light scattering experiments.
Wim Van Criekinge
P VANDERMEEREN
Jean Vanderdeelen
Leon Baert
A1
Journal Article
in
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
1995
1994
Phospholipid-omposition of r-DNA hepatitis-B surface-antigens.
P VANDERMEEREN
Wim Van Criekinge
Jean Vanderdeelen
Leon Baert
A1
Journal Article
in
INTERNATIONAL JOURNAL OF PHARMACEUTICS
1994
Physicochemical characterization of liposomes for use as a biomimeting precipitation reactor
Wim Van Criekinge
MP De Poorter
Paul Van der Meeren
A4
Journal Article
in
MEDEDELINGEN VAN DE FACULTEIT LANDBOUWKUNDIGE EN TOEGEPASTE BIOLOGISCHE WETENSCHAPPEN, UNIVERSITEIT GENT
1994